Off-label use of medicines in Argentina: Who wins and who loses?

Autores
Real, Juan Pablo; Palchik, Valeria; Salamano, Mercedes Cecilia; Traverso, María Luz Elizabet; Palma, Santiago Daniel
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The use of medicines out of the technical specifications or off-label use is legal and a common medical practice all around the world. However, there is a lack of unanimity of criteria and specific regulations about this special situation in a lot of countries. This lack of clear regulation of this particular situation, with strong ethical implications, may involve greater risks to the population and worse health outcomes. The aim of this article is to present a theoretical framework about the problem of off-label use of drugs with particular emphasis on the situation Argentina and the example of the use of Bevacizumab in the treatment of Neovascular Age-Related Macular Degeneration. The role of pharmacist may be crucial ensuring the correct use of medicines, and his intervention gen- erate benefits for both the patient and the institutions in an interdisciplinary approach to pharmacotherapy.
Fil: Real, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; Argentina
Fil: Palchik, Valeria. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Salamano, Mercedes Cecilia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Traverso, María Luz Elizabet. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Palma, Santiago Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; Argentina
Materia
OffLabel
Medicines
Bevacizumab
AMD
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/272766
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Off-label use of medicines in Argentina: Who wins and who loses?Real, Juan PabloPalchik, ValeriaSalamano, Mercedes CeciliaTraverso, María Luz ElizabetPalma, Santiago DanielOffLabelMedicinesBevacizumabAMDhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The use of medicines out of the technical specifications or off-label use is legal and a common medical practice all around the world. However, there is a lack of unanimity of criteria and specific regulations about this special situation in a lot of countries. This lack of clear regulation of this particular situation, with strong ethical implications, may involve greater risks to the population and worse health outcomes. The aim of this article is to present a theoretical framework about the problem of off-label use of drugs with particular emphasis on the situation Argentina and the example of the use of Bevacizumab in the treatment of Neovascular Age-Related Macular Degeneration. The role of pharmacist may be crucial ensuring the correct use of medicines, and his intervention gen- erate benefits for both the patient and the institutions in an interdisciplinary approach to pharmacotherapy.Fil: Real, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; ArgentinaFil: Palchik, Valeria. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Salamano, Mercedes Cecilia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Traverso, María Luz Elizabet. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Palma, Santiago Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; ArgentinaIOP Publishing2012-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/272766Real, Juan Pablo; Palchik, Valeria; Salamano, Mercedes Cecilia; Traverso, María Luz Elizabet; Palma, Santiago Daniel; Off-label use of medicines in Argentina: Who wins and who loses?; IOP Publishing; Pharmaceuticals Policy and Law; 14; 2-4; 12-2012; 209-2221389-28272210-495XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.3233/PPL-120355info:eu-repo/semantics/altIdentifier/doi/10.3233/PPL-120355info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:03:49Zoai:ri.conicet.gov.ar:11336/272766instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:03:49.527CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Off-label use of medicines in Argentina: Who wins and who loses?
title Off-label use of medicines in Argentina: Who wins and who loses?
spellingShingle Off-label use of medicines in Argentina: Who wins and who loses?
Real, Juan Pablo
OffLabel
Medicines
Bevacizumab
AMD
title_short Off-label use of medicines in Argentina: Who wins and who loses?
title_full Off-label use of medicines in Argentina: Who wins and who loses?
title_fullStr Off-label use of medicines in Argentina: Who wins and who loses?
title_full_unstemmed Off-label use of medicines in Argentina: Who wins and who loses?
title_sort Off-label use of medicines in Argentina: Who wins and who loses?
dc.creator.none.fl_str_mv Real, Juan Pablo
Palchik, Valeria
Salamano, Mercedes Cecilia
Traverso, María Luz Elizabet
Palma, Santiago Daniel
author Real, Juan Pablo
author_facet Real, Juan Pablo
Palchik, Valeria
Salamano, Mercedes Cecilia
Traverso, María Luz Elizabet
Palma, Santiago Daniel
author_role author
author2 Palchik, Valeria
Salamano, Mercedes Cecilia
Traverso, María Luz Elizabet
Palma, Santiago Daniel
author2_role author
author
author
author
dc.subject.none.fl_str_mv OffLabel
Medicines
Bevacizumab
AMD
topic OffLabel
Medicines
Bevacizumab
AMD
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The use of medicines out of the technical specifications or off-label use is legal and a common medical practice all around the world. However, there is a lack of unanimity of criteria and specific regulations about this special situation in a lot of countries. This lack of clear regulation of this particular situation, with strong ethical implications, may involve greater risks to the population and worse health outcomes. The aim of this article is to present a theoretical framework about the problem of off-label use of drugs with particular emphasis on the situation Argentina and the example of the use of Bevacizumab in the treatment of Neovascular Age-Related Macular Degeneration. The role of pharmacist may be crucial ensuring the correct use of medicines, and his intervention gen- erate benefits for both the patient and the institutions in an interdisciplinary approach to pharmacotherapy.
Fil: Real, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; Argentina
Fil: Palchik, Valeria. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Salamano, Mercedes Cecilia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Traverso, María Luz Elizabet. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Palma, Santiago Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; Argentina
description The use of medicines out of the technical specifications or off-label use is legal and a common medical practice all around the world. However, there is a lack of unanimity of criteria and specific regulations about this special situation in a lot of countries. This lack of clear regulation of this particular situation, with strong ethical implications, may involve greater risks to the population and worse health outcomes. The aim of this article is to present a theoretical framework about the problem of off-label use of drugs with particular emphasis on the situation Argentina and the example of the use of Bevacizumab in the treatment of Neovascular Age-Related Macular Degeneration. The role of pharmacist may be crucial ensuring the correct use of medicines, and his intervention gen- erate benefits for both the patient and the institutions in an interdisciplinary approach to pharmacotherapy.
publishDate 2012
dc.date.none.fl_str_mv 2012-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/272766
Real, Juan Pablo; Palchik, Valeria; Salamano, Mercedes Cecilia; Traverso, María Luz Elizabet; Palma, Santiago Daniel; Off-label use of medicines in Argentina: Who wins and who loses?; IOP Publishing; Pharmaceuticals Policy and Law; 14; 2-4; 12-2012; 209-222
1389-2827
2210-495X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/272766
identifier_str_mv Real, Juan Pablo; Palchik, Valeria; Salamano, Mercedes Cecilia; Traverso, María Luz Elizabet; Palma, Santiago Daniel; Off-label use of medicines in Argentina: Who wins and who loses?; IOP Publishing; Pharmaceuticals Policy and Law; 14; 2-4; 12-2012; 209-222
1389-2827
2210-495X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.3233/PPL-120355
info:eu-repo/semantics/altIdentifier/doi/10.3233/PPL-120355
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv IOP Publishing
publisher.none.fl_str_mv IOP Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846782382871412736
score 12.982451

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