Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings

Autores
Leathers, James S.; Pisano, María Belén; Ré, Viviana Elizabeth; van Oord, Gertine; Sultan, Amir; Boonstra, Andre; Debes, Jose D.
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradicationworldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usuallyconstrained by testing costs. We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141individuals. The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotypeor viral load (in samples with such information, 90%). The HCV test validated in this study can allow for HCV screening in areas of need when properly used.
Fil: Leathers, James S.. Vanderbilt University; Estados Unidos
Fil: Pisano, María Belén. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: van Oord, Gertine. Erasmus Medical Center; Países Bajos
Fil: Sultan, Amir. Addis Ababa University; Etiopía
Fil: Boonstra, Andre. Erasmus Medical Center; Países Bajos
Fil: Debes, Jose D.. Universidad de Minnesota; Estados Unidos
Materia
HEPATITIS C
RAPID DIAGNOSTIC TEST
RESOURCE-LIMITED
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/112672
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settingsLeathers, James S.Pisano, María BelénRé, Viviana Elizabethvan Oord, GertineSultan, AmirBoonstra, AndreDebes, Jose D.HEPATITIS CRAPID DIAGNOSTIC TESTRESOURCE-LIMITEDhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradicationworldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usuallyconstrained by testing costs. We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141individuals. The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotypeor viral load (in samples with such information, 90%). The HCV test validated in this study can allow for HCV screening in areas of need when properly used.Fil: Leathers, James S.. Vanderbilt University; Estados UnidosFil: Pisano, María Belén. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; ArgentinaFil: van Oord, Gertine. Erasmus Medical Center; Países BajosFil: Sultan, Amir. Addis Ababa University; EtiopíaFil: Boonstra, Andre. Erasmus Medical Center; Países BajosFil: Debes, Jose D.. Universidad de Minnesota; Estados UnidosOxford University Press2019-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/112672Leathers, James S.; Pisano, María Belén; Ré, Viviana Elizabeth; van Oord, Gertine; Sultan, Amir; et al.; Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings; Oxford University Press; International Health; 11; 4; 7-2019; 314-3151876-34131876-3405CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/inthealth/article/11/4/314/5375832info:eu-repo/semantics/altIdentifier/doi/10.1093/inthealth/ihy101info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:54:10Zoai:ri.conicet.gov.ar:11336/112672instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:54:10.609CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
title Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
spellingShingle Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
Leathers, James S.
HEPATITIS C
RAPID DIAGNOSTIC TEST
RESOURCE-LIMITED
title_short Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
title_full Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
title_fullStr Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
title_full_unstemmed Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
title_sort Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings
dc.creator.none.fl_str_mv Leathers, James S.
Pisano, María Belén
Ré, Viviana Elizabeth
van Oord, Gertine
Sultan, Amir
Boonstra, Andre
Debes, Jose D.
author Leathers, James S.
author_facet Leathers, James S.
Pisano, María Belén
Ré, Viviana Elizabeth
van Oord, Gertine
Sultan, Amir
Boonstra, Andre
Debes, Jose D.
author_role author
author2 Pisano, María Belén
Ré, Viviana Elizabeth
van Oord, Gertine
Sultan, Amir
Boonstra, Andre
Debes, Jose D.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv HEPATITIS C
RAPID DIAGNOSTIC TEST
RESOURCE-LIMITED
topic HEPATITIS C
RAPID DIAGNOSTIC TEST
RESOURCE-LIMITED
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradicationworldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usuallyconstrained by testing costs. We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141individuals. The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotypeor viral load (in samples with such information, 90%). The HCV test validated in this study can allow for HCV screening in areas of need when properly used.
Fil: Leathers, James S.. Vanderbilt University; Estados Unidos
Fil: Pisano, María Belén. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: van Oord, Gertine. Erasmus Medical Center; Países Bajos
Fil: Sultan, Amir. Addis Ababa University; Etiopía
Fil: Boonstra, Andre. Erasmus Medical Center; Países Bajos
Fil: Debes, Jose D.. Universidad de Minnesota; Estados Unidos
description Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradicationworldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usuallyconstrained by testing costs. We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141individuals. The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotypeor viral load (in samples with such information, 90%). The HCV test validated in this study can allow for HCV screening in areas of need when properly used.
publishDate 2019
dc.date.none.fl_str_mv 2019-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/112672
Leathers, James S.; Pisano, María Belén; Ré, Viviana Elizabeth; van Oord, Gertine; Sultan, Amir; et al.; Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings; Oxford University Press; International Health; 11; 4; 7-2019; 314-315
1876-3413
1876-3405
CONICET Digital
CONICET
url http://hdl.handle.net/11336/112672
identifier_str_mv Leathers, James S.; Pisano, María Belén; Ré, Viviana Elizabeth; van Oord, Gertine; Sultan, Amir; et al.; Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings; Oxford University Press; International Health; 11; 4; 7-2019; 314-315
1876-3413
1876-3405
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/inthealth/article/11/4/314/5375832
info:eu-repo/semantics/altIdentifier/doi/10.1093/inthealth/ihy101
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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