Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface

Autores
Colqui Quiroga, Mónica Vanesa; Monzon, Lorena Maria Aranzazu; Yudi, Lidia Mabel
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The effect of triflupromazine (TFP) on molecular packing of distearoylphosphatidylglycerol (DSPG), adsorbed at the water/1,2-dichloroethane interface, was investigated using cyclic voltammetry (CV) and surface pressure-molecular area isotherm. TFP partition in the DSPG monolayer changes the structure of the film. The results indicate that a fluidizing effect, dependent on the time and the drug concentration, takes place leading to an increase in the permeability of the film. This effect is produced by TFP either from the organic or from the aqueous phase due to the amphiphilic nature of this drug. Nevertheless, the expansion of the film is enhanced when TFP acts from the aqueous phase
Fil: Colqui Quiroga, Mónica Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Monzon, Lorena Maria Aranzazu. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia
Anionic Phospholipid Monolayers
Electrochemistry at Liquid/Liquid Interfaces
Phenothiazines
Surface Pressure Isotherms
Triflupromazine
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/70324
Acceder
id CONICETDig_5fca865c305f35bef62ab894c471f6df
oai_identifier_str oai:ri.conicet.gov.ar:11336/70324
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interfaceColqui Quiroga, Mónica VanesaMonzon, Lorena Maria AranzazuYudi, Lidia MabelAnionic Phospholipid MonolayersElectrochemistry at Liquid/Liquid InterfacesPhenothiazinesSurface Pressure IsothermsTriflupromazinehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The effect of triflupromazine (TFP) on molecular packing of distearoylphosphatidylglycerol (DSPG), adsorbed at the water/1,2-dichloroethane interface, was investigated using cyclic voltammetry (CV) and surface pressure-molecular area isotherm. TFP partition in the DSPG monolayer changes the structure of the film. The results indicate that a fluidizing effect, dependent on the time and the drug concentration, takes place leading to an increase in the permeability of the film. This effect is produced by TFP either from the organic or from the aqueous phase due to the amphiphilic nature of this drug. Nevertheless, the expansion of the film is enhanced when TFP acts from the aqueous phaseFil: Colqui Quiroga, Mónica Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Monzon, Lorena Maria Aranzazu. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaPergamon-Elsevier Science Ltd2010-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/70324Colqui Quiroga, Mónica Vanesa; Monzon, Lorena Maria Aranzazu; Yudi, Lidia Mabel; Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface; Pergamon-Elsevier Science Ltd; Electrochimica Acta; 55; 20; 8-2010; 5840-58460013-4686CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0013468610007127info:eu-repo/semantics/altIdentifier/doi/10.1016/j.electacta.2010.05.033info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:51:09Zoai:ri.conicet.gov.ar:11336/70324instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:51:09.718CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
title Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
spellingShingle Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
Colqui Quiroga, Mónica Vanesa
Anionic Phospholipid Monolayers
Electrochemistry at Liquid/Liquid Interfaces
Phenothiazines
Surface Pressure Isotherms
Triflupromazine
title_short Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
title_full Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
title_fullStr Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
title_full_unstemmed Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
title_sort Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface
dc.creator.none.fl_str_mv Colqui Quiroga, Mónica Vanesa
Monzon, Lorena Maria Aranzazu
Yudi, Lidia Mabel
author Colqui Quiroga, Mónica Vanesa
author_facet Colqui Quiroga, Mónica Vanesa
Monzon, Lorena Maria Aranzazu
Yudi, Lidia Mabel
author_role author
author2 Monzon, Lorena Maria Aranzazu
Yudi, Lidia Mabel
author2_role author
author
dc.subject.none.fl_str_mv Anionic Phospholipid Monolayers
Electrochemistry at Liquid/Liquid Interfaces
Phenothiazines
Surface Pressure Isotherms
Triflupromazine
topic Anionic Phospholipid Monolayers
Electrochemistry at Liquid/Liquid Interfaces
Phenothiazines
Surface Pressure Isotherms
Triflupromazine
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The effect of triflupromazine (TFP) on molecular packing of distearoylphosphatidylglycerol (DSPG), adsorbed at the water/1,2-dichloroethane interface, was investigated using cyclic voltammetry (CV) and surface pressure-molecular area isotherm. TFP partition in the DSPG monolayer changes the structure of the film. The results indicate that a fluidizing effect, dependent on the time and the drug concentration, takes place leading to an increase in the permeability of the film. This effect is produced by TFP either from the organic or from the aqueous phase due to the amphiphilic nature of this drug. Nevertheless, the expansion of the film is enhanced when TFP acts from the aqueous phase
Fil: Colqui Quiroga, Mónica Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Monzon, Lorena Maria Aranzazu. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description The effect of triflupromazine (TFP) on molecular packing of distearoylphosphatidylglycerol (DSPG), adsorbed at the water/1,2-dichloroethane interface, was investigated using cyclic voltammetry (CV) and surface pressure-molecular area isotherm. TFP partition in the DSPG monolayer changes the structure of the film. The results indicate that a fluidizing effect, dependent on the time and the drug concentration, takes place leading to an increase in the permeability of the film. This effect is produced by TFP either from the organic or from the aqueous phase due to the amphiphilic nature of this drug. Nevertheless, the expansion of the film is enhanced when TFP acts from the aqueous phase
publishDate 2010
dc.date.none.fl_str_mv 2010-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/70324
Colqui Quiroga, Mónica Vanesa; Monzon, Lorena Maria Aranzazu; Yudi, Lidia Mabel; Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface; Pergamon-Elsevier Science Ltd; Electrochimica Acta; 55; 20; 8-2010; 5840-5846
0013-4686
CONICET Digital
CONICET
url http://hdl.handle.net/11336/70324
identifier_str_mv Colqui Quiroga, Mónica Vanesa; Monzon, Lorena Maria Aranzazu; Yudi, Lidia Mabel; Interaction of triflupromazine with distearoylphosphatidylglycerol films studied by surface pressure isotherms and cyclic voltammetry at a 1,2-dichloroethane/water interface; Pergamon-Elsevier Science Ltd; Electrochimica Acta; 55; 20; 8-2010; 5840-5846
0013-4686
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0013468610007127
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.electacta.2010.05.033
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269076961886208
score 13.13397

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