Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina
- Autores
- Urtasun, María; Daray, Federico Manuel; Teti, Germán Leandro; Coppolillo, Fernando Enrique; Herlax, Gabriela; Saba, Guillermo; Rubinstein, Adolfo Luis; Araya, Ricardo; Irazola, Vilma
- Año de publicación
- 2019
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background: The Patient Health Questionnaire-9 (PHQ-9) is a brief tool to assess the presence and severity of depressive symptoms. This study aimed to validate and calibrate the PHQ-9 to determine appropriate cut-off points for different degrees of severity of depression in Argentina. Methods: We conducted a cross-sectional study on an intentional sample of adult ambulatory care patients with different degrees of severity of depression. All patients who completed the PHQ-9 were further interviewed by a trained clinician with the Mini International Neuropsychiatric Interview (MINI) and the Beck Depression Inventory-II (BDI-II). Reliability and validity tests, including receiver operating curve analysis, were performed. Results: One hundred sixty-nine patients were recruited with a mean age of 47.4 years (SD = 14.8), of whom 102 were females (60.4%). The local PHQ-9 had high internal consistency (Cronbach's alpha = 0.87) and satisfactory convergent validity with the BDI-II scale [Pearson's correlation = 0.88 (p < 0.01)]. For the diagnosis of Major Depressive Episode (MDE) according to the MINI, a PHQ-9 ≥ 8 was the optimal cut-off point found (sensitivity 88.2%, specificity 86.6%, PPV 90.91%). The local version of PHQ-9 showed good ability to discriminate among depression severity categories according to the BDI-II scale. The best cut off points were 6-8 for mild cases, 9-14 for moderate and 15 or more for severe depressive symptoms respectively. Conclusions: The Argentine version of the PHQ-9 questionnaire has shown acceptable validity and reliability for both screening and severity assessment of depressive symptoms.
Fil: Urtasun, María. Instituto de Efectividad Clínica y Sanitaria; Argentina. Universidad de Alcalá; España
Fil: Daray, Federico Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
Fil: Teti, Germán Leandro. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital Neuropsiquiátrico Braulio Aurelio Moyano; Argentina
Fil: Coppolillo, Fernando Enrique. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Herlax, Gabriela. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Saba, Guillermo. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Rubinstein, Adolfo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Araya, Ricardo. London School of Hygiene and Tropical Medicine; Reino Unido
Fil: Irazola, Vilma. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina - Materia
-
ARGENTINA
DEPRESSION
MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW
PATIENT HEALTH QUESTIONNAIRE-9
PSYCHOMETRICS
SCREENING INSTRUMENTS - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/147518
Ver los metadatos del registro completo
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Validation and calibration of the patient health questionnaire (PHQ-9) in ArgentinaUrtasun, MaríaDaray, Federico ManuelTeti, Germán LeandroCoppolillo, Fernando EnriqueHerlax, GabrielaSaba, GuillermoRubinstein, Adolfo LuisAraya, RicardoIrazola, VilmaARGENTINADEPRESSIONMINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEWPATIENT HEALTH QUESTIONNAIRE-9PSYCHOMETRICSSCREENING INSTRUMENTShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: The Patient Health Questionnaire-9 (PHQ-9) is a brief tool to assess the presence and severity of depressive symptoms. This study aimed to validate and calibrate the PHQ-9 to determine appropriate cut-off points for different degrees of severity of depression in Argentina. Methods: We conducted a cross-sectional study on an intentional sample of adult ambulatory care patients with different degrees of severity of depression. All patients who completed the PHQ-9 were further interviewed by a trained clinician with the Mini International Neuropsychiatric Interview (MINI) and the Beck Depression Inventory-II (BDI-II). Reliability and validity tests, including receiver operating curve analysis, were performed. Results: One hundred sixty-nine patients were recruited with a mean age of 47.4 years (SD = 14.8), of whom 102 were females (60.4%). The local PHQ-9 had high internal consistency (Cronbach's alpha = 0.87) and satisfactory convergent validity with the BDI-II scale [Pearson's correlation = 0.88 (p < 0.01)]. For the diagnosis of Major Depressive Episode (MDE) according to the MINI, a PHQ-9 ≥ 8 was the optimal cut-off point found (sensitivity 88.2%, specificity 86.6%, PPV 90.91%). The local version of PHQ-9 showed good ability to discriminate among depression severity categories according to the BDI-II scale. The best cut off points were 6-8 for mild cases, 9-14 for moderate and 15 or more for severe depressive symptoms respectively. Conclusions: The Argentine version of the PHQ-9 questionnaire has shown acceptable validity and reliability for both screening and severity assessment of depressive symptoms.Fil: Urtasun, María. Instituto de Efectividad Clínica y Sanitaria; Argentina. Universidad de Alcalá; EspañaFil: Daray, Federico Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; ArgentinaFil: Teti, Germán Leandro. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital Neuropsiquiátrico Braulio Aurelio Moyano; ArgentinaFil: Coppolillo, Fernando Enrique. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaFil: Herlax, Gabriela. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaFil: Saba, Guillermo. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Rubinstein, Adolfo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Araya, Ricardo. London School of Hygiene and Tropical Medicine; Reino UnidoFil: Irazola, Vilma. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaBioMed Central2019-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/147518Urtasun, María; Daray, Federico Manuel; Teti, Germán Leandro; Coppolillo, Fernando Enrique; Herlax, Gabriela; et al.; Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina; BioMed Central; Bmc Psychiatry; 19; 1; 9-2019; 1-101471-244XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-019-2262-9info:eu-repo/semantics/altIdentifier/doi/10.1186/s12888-019-2262-9info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:36:00Zoai:ri.conicet.gov.ar:11336/147518instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:36:00.707CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
title |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
spellingShingle |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina Urtasun, María ARGENTINA DEPRESSION MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW PATIENT HEALTH QUESTIONNAIRE-9 PSYCHOMETRICS SCREENING INSTRUMENTS |
title_short |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
title_full |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
title_fullStr |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
title_full_unstemmed |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
title_sort |
Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina |
dc.creator.none.fl_str_mv |
Urtasun, María Daray, Federico Manuel Teti, Germán Leandro Coppolillo, Fernando Enrique Herlax, Gabriela Saba, Guillermo Rubinstein, Adolfo Luis Araya, Ricardo Irazola, Vilma |
author |
Urtasun, María |
author_facet |
Urtasun, María Daray, Federico Manuel Teti, Germán Leandro Coppolillo, Fernando Enrique Herlax, Gabriela Saba, Guillermo Rubinstein, Adolfo Luis Araya, Ricardo Irazola, Vilma |
author_role |
author |
author2 |
Daray, Federico Manuel Teti, Germán Leandro Coppolillo, Fernando Enrique Herlax, Gabriela Saba, Guillermo Rubinstein, Adolfo Luis Araya, Ricardo Irazola, Vilma |
author2_role |
author author author author author author author author |
dc.subject.none.fl_str_mv |
ARGENTINA DEPRESSION MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW PATIENT HEALTH QUESTIONNAIRE-9 PSYCHOMETRICS SCREENING INSTRUMENTS |
topic |
ARGENTINA DEPRESSION MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW PATIENT HEALTH QUESTIONNAIRE-9 PSYCHOMETRICS SCREENING INSTRUMENTS |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Background: The Patient Health Questionnaire-9 (PHQ-9) is a brief tool to assess the presence and severity of depressive symptoms. This study aimed to validate and calibrate the PHQ-9 to determine appropriate cut-off points for different degrees of severity of depression in Argentina. Methods: We conducted a cross-sectional study on an intentional sample of adult ambulatory care patients with different degrees of severity of depression. All patients who completed the PHQ-9 were further interviewed by a trained clinician with the Mini International Neuropsychiatric Interview (MINI) and the Beck Depression Inventory-II (BDI-II). Reliability and validity tests, including receiver operating curve analysis, were performed. Results: One hundred sixty-nine patients were recruited with a mean age of 47.4 years (SD = 14.8), of whom 102 were females (60.4%). The local PHQ-9 had high internal consistency (Cronbach's alpha = 0.87) and satisfactory convergent validity with the BDI-II scale [Pearson's correlation = 0.88 (p < 0.01)]. For the diagnosis of Major Depressive Episode (MDE) according to the MINI, a PHQ-9 ≥ 8 was the optimal cut-off point found (sensitivity 88.2%, specificity 86.6%, PPV 90.91%). The local version of PHQ-9 showed good ability to discriminate among depression severity categories according to the BDI-II scale. The best cut off points were 6-8 for mild cases, 9-14 for moderate and 15 or more for severe depressive symptoms respectively. Conclusions: The Argentine version of the PHQ-9 questionnaire has shown acceptable validity and reliability for both screening and severity assessment of depressive symptoms. Fil: Urtasun, María. Instituto de Efectividad Clínica y Sanitaria; Argentina. Universidad de Alcalá; España Fil: Daray, Federico Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina Fil: Teti, Germán Leandro. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital Neuropsiquiátrico Braulio Aurelio Moyano; Argentina Fil: Coppolillo, Fernando Enrique. Universidad de Buenos Aires. Facultad de Medicina; Argentina Fil: Herlax, Gabriela. Universidad de Buenos Aires. Facultad de Medicina; Argentina Fil: Saba, Guillermo. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Rubinstein, Adolfo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina Fil: Araya, Ricardo. London School of Hygiene and Tropical Medicine; Reino Unido Fil: Irazola, Vilma. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina |
description |
Background: The Patient Health Questionnaire-9 (PHQ-9) is a brief tool to assess the presence and severity of depressive symptoms. This study aimed to validate and calibrate the PHQ-9 to determine appropriate cut-off points for different degrees of severity of depression in Argentina. Methods: We conducted a cross-sectional study on an intentional sample of adult ambulatory care patients with different degrees of severity of depression. All patients who completed the PHQ-9 were further interviewed by a trained clinician with the Mini International Neuropsychiatric Interview (MINI) and the Beck Depression Inventory-II (BDI-II). Reliability and validity tests, including receiver operating curve analysis, were performed. Results: One hundred sixty-nine patients were recruited with a mean age of 47.4 years (SD = 14.8), of whom 102 were females (60.4%). The local PHQ-9 had high internal consistency (Cronbach's alpha = 0.87) and satisfactory convergent validity with the BDI-II scale [Pearson's correlation = 0.88 (p < 0.01)]. For the diagnosis of Major Depressive Episode (MDE) according to the MINI, a PHQ-9 ≥ 8 was the optimal cut-off point found (sensitivity 88.2%, specificity 86.6%, PPV 90.91%). The local version of PHQ-9 showed good ability to discriminate among depression severity categories according to the BDI-II scale. The best cut off points were 6-8 for mild cases, 9-14 for moderate and 15 or more for severe depressive symptoms respectively. Conclusions: The Argentine version of the PHQ-9 questionnaire has shown acceptable validity and reliability for both screening and severity assessment of depressive symptoms. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-09 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/147518 Urtasun, María; Daray, Federico Manuel; Teti, Germán Leandro; Coppolillo, Fernando Enrique; Herlax, Gabriela; et al.; Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina; BioMed Central; Bmc Psychiatry; 19; 1; 9-2019; 1-10 1471-244X CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/147518 |
identifier_str_mv |
Urtasun, María; Daray, Federico Manuel; Teti, Germán Leandro; Coppolillo, Fernando Enrique; Herlax, Gabriela; et al.; Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina; BioMed Central; Bmc Psychiatry; 19; 1; 9-2019; 1-10 1471-244X CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-019-2262-9 info:eu-repo/semantics/altIdentifier/doi/10.1186/s12888-019-2262-9 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |