The efficiency of potassium removal during bicarbonate hemodialysis

Autores
Capdevila, M.; Martinez Ruiz, I.; Ferrer, C.; Monllor, F.; Ludjvick, C.; Garcia, Nestor Horacio; Juncos, Luis Isaias
Año de publicación
2005
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Patients on chronic hemodialysis often portray high serum [K+]. Although dietary excesses are evident in many cases, in others, the cause of hyperkalemia cannot be identified. In such cases, hyperkalemia could result from decreased potassium removal during dialysis. This situation could occur if alkalinization of body fluids during dialysis would drive potassium into the cell, thus decreasing the potassium gradient across the dialysis membrane. In 35 chronic hemodialysis patients, we compared two dialysis sessions performed 7 days apart. Bicarbonate or acetate as dialysate buffers were randomly assigned for the first dialysis. The buffer was switched for the second dialysis. Serum [K+], [HCO3-], and pH were measured in samples drawn before dialysis; 60, 120, 180, and 240 min into dialysis; and 60 and 90 min after dialysis. The potassium removed was measured in the dialysate. During the first 2 hr, serum [K+] decreased equally with both types of dialysates but declined more during the last 2 hr with bicarbonate dialysis. After dialysis, the serum [K+] rebounded higher with bicarbonate bringing the serum [K+] up to par with acetate. The lower serum [K+] through the second half of bicarbonate dialysis did not impair potassium removal (295.9 ± 9.6 mmol with bicarbonate and 299.0 ± 14.4 mmol with acetate). The measured serum K+ concentrations correlated with serum [HCO3-] and blood pH during bicarbonate dialysis but not during acetate dialysis. Alkalinization induced by bicarbonate administration may cause redistribution of K during bicarbonate dialysis but this does not impair its removal. The more marked lowering of potassium during bicarbonate dialysis occurs late in dialysis, when exchange is negligible because of a low gradient.
Fil: Capdevila, M.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Martinez Ruiz, I.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Ferrer, C.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Monllor, F.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Ludjvick, C.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Garcia, Nestor Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Juncos, Luis Isaias. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Materia
ACETATE DIALYSIS
BICARBONATE DIALYSIS
HYPERKALEMIA
POTASSIUM REMOVAL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/114662
Acceder
id CONICETDig_5e584fb80bd981e822cf388c78295606
oai_identifier_str oai:ri.conicet.gov.ar:11336/114662
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The efficiency of potassium removal during bicarbonate hemodialysisCapdevila, M.Martinez Ruiz, I.Ferrer, C.Monllor, F.Ludjvick, C.Garcia, Nestor HoracioJuncos, Luis IsaiasACETATE DIALYSISBICARBONATE DIALYSISHYPERKALEMIAPOTASSIUM REMOVALhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Patients on chronic hemodialysis often portray high serum [K+]. Although dietary excesses are evident in many cases, in others, the cause of hyperkalemia cannot be identified. In such cases, hyperkalemia could result from decreased potassium removal during dialysis. This situation could occur if alkalinization of body fluids during dialysis would drive potassium into the cell, thus decreasing the potassium gradient across the dialysis membrane. In 35 chronic hemodialysis patients, we compared two dialysis sessions performed 7 days apart. Bicarbonate or acetate as dialysate buffers were randomly assigned for the first dialysis. The buffer was switched for the second dialysis. Serum [K+], [HCO3-], and pH were measured in samples drawn before dialysis; 60, 120, 180, and 240 min into dialysis; and 60 and 90 min after dialysis. The potassium removed was measured in the dialysate. During the first 2 hr, serum [K+] decreased equally with both types of dialysates but declined more during the last 2 hr with bicarbonate dialysis. After dialysis, the serum [K+] rebounded higher with bicarbonate bringing the serum [K+] up to par with acetate. The lower serum [K+] through the second half of bicarbonate dialysis did not impair potassium removal (295.9 ± 9.6 mmol with bicarbonate and 299.0 ± 14.4 mmol with acetate). The measured serum K+ concentrations correlated with serum [HCO3-] and blood pH during bicarbonate dialysis but not during acetate dialysis. Alkalinization induced by bicarbonate administration may cause redistribution of K during bicarbonate dialysis but this does not impair its removal. The more marked lowering of potassium during bicarbonate dialysis occurs late in dialysis, when exchange is negligible because of a low gradient.Fil: Capdevila, M.. Fundación Robert Cade, Instituto de Especialidades Médicas; ArgentinaFil: Martinez Ruiz, I.. Fundación Robert Cade, Instituto de Especialidades Médicas; ArgentinaFil: Ferrer, C.. Fundación Robert Cade, Instituto de Especialidades Médicas; ArgentinaFil: Monllor, F.. Fundación Robert Cade, Instituto de Especialidades Médicas; ArgentinaFil: Ludjvick, C.. Fundación Robert Cade, Instituto de Especialidades Médicas; ArgentinaFil: Garcia, Nestor Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Juncos, Luis Isaias. Fundación Robert Cade, Instituto de Especialidades Médicas; ArgentinaWiley Blackwell Publishing, Inc2005-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/114662Capdevila, M.; Martinez Ruiz, I.; Ferrer, C.; Monllor, F.; Ludjvick, C.; et al.; The efficiency of potassium removal during bicarbonate hemodialysis; Wiley Blackwell Publishing, Inc; Hemodialysis International; 9; 3; 7-2005; 296-3021492-75351542-4758CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1492-7535.2005.01144.xinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1492-7535.2005.01144.xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:53:34Zoai:ri.conicet.gov.ar:11336/114662instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:53:34.653CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The efficiency of potassium removal during bicarbonate hemodialysis
title The efficiency of potassium removal during bicarbonate hemodialysis
spellingShingle The efficiency of potassium removal during bicarbonate hemodialysis
Capdevila, M.
ACETATE DIALYSIS
BICARBONATE DIALYSIS
HYPERKALEMIA
POTASSIUM REMOVAL
title_short The efficiency of potassium removal during bicarbonate hemodialysis
title_full The efficiency of potassium removal during bicarbonate hemodialysis
title_fullStr The efficiency of potassium removal during bicarbonate hemodialysis
title_full_unstemmed The efficiency of potassium removal during bicarbonate hemodialysis
title_sort The efficiency of potassium removal during bicarbonate hemodialysis
dc.creator.none.fl_str_mv Capdevila, M.
Martinez Ruiz, I.
Ferrer, C.
Monllor, F.
Ludjvick, C.
Garcia, Nestor Horacio
Juncos, Luis Isaias
author Capdevila, M.
author_facet Capdevila, M.
Martinez Ruiz, I.
Ferrer, C.
Monllor, F.
Ludjvick, C.
Garcia, Nestor Horacio
Juncos, Luis Isaias
author_role author
author2 Martinez Ruiz, I.
Ferrer, C.
Monllor, F.
Ludjvick, C.
Garcia, Nestor Horacio
Juncos, Luis Isaias
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ACETATE DIALYSIS
BICARBONATE DIALYSIS
HYPERKALEMIA
POTASSIUM REMOVAL
topic ACETATE DIALYSIS
BICARBONATE DIALYSIS
HYPERKALEMIA
POTASSIUM REMOVAL
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Patients on chronic hemodialysis often portray high serum [K+]. Although dietary excesses are evident in many cases, in others, the cause of hyperkalemia cannot be identified. In such cases, hyperkalemia could result from decreased potassium removal during dialysis. This situation could occur if alkalinization of body fluids during dialysis would drive potassium into the cell, thus decreasing the potassium gradient across the dialysis membrane. In 35 chronic hemodialysis patients, we compared two dialysis sessions performed 7 days apart. Bicarbonate or acetate as dialysate buffers were randomly assigned for the first dialysis. The buffer was switched for the second dialysis. Serum [K+], [HCO3-], and pH were measured in samples drawn before dialysis; 60, 120, 180, and 240 min into dialysis; and 60 and 90 min after dialysis. The potassium removed was measured in the dialysate. During the first 2 hr, serum [K+] decreased equally with both types of dialysates but declined more during the last 2 hr with bicarbonate dialysis. After dialysis, the serum [K+] rebounded higher with bicarbonate bringing the serum [K+] up to par with acetate. The lower serum [K+] through the second half of bicarbonate dialysis did not impair potassium removal (295.9 ± 9.6 mmol with bicarbonate and 299.0 ± 14.4 mmol with acetate). The measured serum K+ concentrations correlated with serum [HCO3-] and blood pH during bicarbonate dialysis but not during acetate dialysis. Alkalinization induced by bicarbonate administration may cause redistribution of K during bicarbonate dialysis but this does not impair its removal. The more marked lowering of potassium during bicarbonate dialysis occurs late in dialysis, when exchange is negligible because of a low gradient.
Fil: Capdevila, M.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Martinez Ruiz, I.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Ferrer, C.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Monllor, F.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Ludjvick, C.. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
Fil: Garcia, Nestor Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Juncos, Luis Isaias. Fundación Robert Cade, Instituto de Especialidades Médicas; Argentina
description Patients on chronic hemodialysis often portray high serum [K+]. Although dietary excesses are evident in many cases, in others, the cause of hyperkalemia cannot be identified. In such cases, hyperkalemia could result from decreased potassium removal during dialysis. This situation could occur if alkalinization of body fluids during dialysis would drive potassium into the cell, thus decreasing the potassium gradient across the dialysis membrane. In 35 chronic hemodialysis patients, we compared two dialysis sessions performed 7 days apart. Bicarbonate or acetate as dialysate buffers were randomly assigned for the first dialysis. The buffer was switched for the second dialysis. Serum [K+], [HCO3-], and pH were measured in samples drawn before dialysis; 60, 120, 180, and 240 min into dialysis; and 60 and 90 min after dialysis. The potassium removed was measured in the dialysate. During the first 2 hr, serum [K+] decreased equally with both types of dialysates but declined more during the last 2 hr with bicarbonate dialysis. After dialysis, the serum [K+] rebounded higher with bicarbonate bringing the serum [K+] up to par with acetate. The lower serum [K+] through the second half of bicarbonate dialysis did not impair potassium removal (295.9 ± 9.6 mmol with bicarbonate and 299.0 ± 14.4 mmol with acetate). The measured serum K+ concentrations correlated with serum [HCO3-] and blood pH during bicarbonate dialysis but not during acetate dialysis. Alkalinization induced by bicarbonate administration may cause redistribution of K during bicarbonate dialysis but this does not impair its removal. The more marked lowering of potassium during bicarbonate dialysis occurs late in dialysis, when exchange is negligible because of a low gradient.
publishDate 2005
dc.date.none.fl_str_mv 2005-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/114662
Capdevila, M.; Martinez Ruiz, I.; Ferrer, C.; Monllor, F.; Ludjvick, C.; et al.; The efficiency of potassium removal during bicarbonate hemodialysis; Wiley Blackwell Publishing, Inc; Hemodialysis International; 9; 3; 7-2005; 296-302
1492-7535
1542-4758
CONICET Digital
CONICET
url http://hdl.handle.net/11336/114662
identifier_str_mv Capdevila, M.; Martinez Ruiz, I.; Ferrer, C.; Monllor, F.; Ludjvick, C.; et al.; The efficiency of potassium removal during bicarbonate hemodialysis; Wiley Blackwell Publishing, Inc; Hemodialysis International; 9; 3; 7-2005; 296-302
1492-7535
1542-4758
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1492-7535.2005.01144.x
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1492-7535.2005.01144.x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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