Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutica...

Autores
Hernández, Silvia Raquel; Ribero, Gustavo Gabriel; Goicoechea, Hector Casimiro
Año de publicación
2003
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Vitamins B6 (VB6) and B12 (VB12) were simultaneously determined in pharmaceutical preparations by using square wave voltametry (SWV) together with artificial neural networks (ANNs). Supporting electrolyte solution, pH and voltametric technique were optimised. The calibration set was built with several artificial samples containing both active ingredients and excipients. Deviations from linearity were observed for both analytes. It is probably due to interactions among the electro active components and competition by the electrode surface, fact that supports the use of ANNs. Recoveries when analysing a nine sample validation set, of 100.2 and 96.4 were calculated for VB6 and VB12, respectively. Commercial samples were analysed with reasonably good results considering the complexity of the mixture studied.
Fil: Hernández, Silvia Raquel. Universidad Nacional del Litoral; Argentina
Fil: Ribero, Gustavo Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina
Materia
B6 Vitamin
B12 Vitmin
Square Wave Voltammetry
Partial Least Squares
Artificial Neural Networks
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/28571
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparationsHernández, Silvia RaquelRibero, Gustavo GabrielGoicoechea, Hector CasimiroB6 VitaminB12 VitminSquare Wave VoltammetryPartial Least SquaresArtificial Neural NetworksVitamins B6 (VB6) and B12 (VB12) were simultaneously determined in pharmaceutical preparations by using square wave voltametry (SWV) together with artificial neural networks (ANNs). Supporting electrolyte solution, pH and voltametric technique were optimised. The calibration set was built with several artificial samples containing both active ingredients and excipients. Deviations from linearity were observed for both analytes. It is probably due to interactions among the electro active components and competition by the electrode surface, fact that supports the use of ANNs. Recoveries when analysing a nine sample validation set, of 100.2 and 96.4 were calculated for VB6 and VB12, respectively. Commercial samples were analysed with reasonably good results considering the complexity of the mixture studied.Fil: Hernández, Silvia Raquel. Universidad Nacional del Litoral; ArgentinaFil: Ribero, Gustavo Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; ArgentinaElsevier Science2003-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/28571Hernández, Silvia Raquel; Ribero, Gustavo Gabriel; Goicoechea, Hector Casimiro; Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations; Elsevier Science; Talanta; 61; 5-2003; 743-7530039-9140CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/S0039-9140(03)00335-7info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:47:52Zoai:ri.conicet.gov.ar:11336/28571instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:47:53.186CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
title Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
spellingShingle Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
Hernández, Silvia Raquel
B6 Vitamin
B12 Vitmin
Square Wave Voltammetry
Partial Least Squares
Artificial Neural Networks
title_short Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
title_full Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
title_fullStr Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
title_full_unstemmed Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
title_sort Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations
dc.creator.none.fl_str_mv Hernández, Silvia Raquel
Ribero, Gustavo Gabriel
Goicoechea, Hector Casimiro
author Hernández, Silvia Raquel
author_facet Hernández, Silvia Raquel
Ribero, Gustavo Gabriel
Goicoechea, Hector Casimiro
author_role author
author2 Ribero, Gustavo Gabriel
Goicoechea, Hector Casimiro
author2_role author
author
dc.subject.none.fl_str_mv B6 Vitamin
B12 Vitmin
Square Wave Voltammetry
Partial Least Squares
Artificial Neural Networks
topic B6 Vitamin
B12 Vitmin
Square Wave Voltammetry
Partial Least Squares
Artificial Neural Networks
dc.description.none.fl_txt_mv Vitamins B6 (VB6) and B12 (VB12) were simultaneously determined in pharmaceutical preparations by using square wave voltametry (SWV) together with artificial neural networks (ANNs). Supporting electrolyte solution, pH and voltametric technique were optimised. The calibration set was built with several artificial samples containing both active ingredients and excipients. Deviations from linearity were observed for both analytes. It is probably due to interactions among the electro active components and competition by the electrode surface, fact that supports the use of ANNs. Recoveries when analysing a nine sample validation set, of 100.2 and 96.4 were calculated for VB6 and VB12, respectively. Commercial samples were analysed with reasonably good results considering the complexity of the mixture studied.
Fil: Hernández, Silvia Raquel. Universidad Nacional del Litoral; Argentina
Fil: Ribero, Gustavo Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina
description Vitamins B6 (VB6) and B12 (VB12) were simultaneously determined in pharmaceutical preparations by using square wave voltametry (SWV) together with artificial neural networks (ANNs). Supporting electrolyte solution, pH and voltametric technique were optimised. The calibration set was built with several artificial samples containing both active ingredients and excipients. Deviations from linearity were observed for both analytes. It is probably due to interactions among the electro active components and competition by the electrode surface, fact that supports the use of ANNs. Recoveries when analysing a nine sample validation set, of 100.2 and 96.4 were calculated for VB6 and VB12, respectively. Commercial samples were analysed with reasonably good results considering the complexity of the mixture studied.
publishDate 2003
dc.date.none.fl_str_mv 2003-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/28571
Hernández, Silvia Raquel; Ribero, Gustavo Gabriel; Goicoechea, Hector Casimiro; Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations; Elsevier Science; Talanta; 61; 5-2003; 743-753
0039-9140
CONICET Digital
CONICET
url http://hdl.handle.net/11336/28571
identifier_str_mv Hernández, Silvia Raquel; Ribero, Gustavo Gabriel; Goicoechea, Hector Casimiro; Enhanced application of square wave voltammetry with glassy carbon electrode coupled to multivariate calibration tools for the determination of B6 and B12 vitamins in pharmaceutical preparations; Elsevier Science; Talanta; 61; 5-2003; 743-753
0039-9140
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/S0039-9140(03)00335-7
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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