Biogenic amines in the testis: Sources, receptors and actions

Autores
Frungieri, Monica Beatriz; Mayerhofer, Artur
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Biogenic amines are signaling molecules with multiple roles in the centralnervous system and in peripheral organs, including the gonads. A series ofstudies indicated that these molecules, their biosynthetic enzymes and theirreceptors are present in the testis and that they are involved in the regulation ofmale reproductive physiology and/or pathology. This mini-review aims tosummarize the current knowledge in this field and to pinpoint existingresearch gaps. We suggest that the widespread clinical use of pharmacologicalagonists/antagonists of these signaling molecules, calls for new investigations inthis area. They are necessary to evaluate the relevance of biogenic amines forhuman male fertility and infertility, as well as the potential value of at least one ofthem as an anti-aging compound in the testis.
Fil: Frungieri, Monica Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Mayerhofer, Artur. Ludwig Maximilians Universitat; Alemania
Materia
CATECHOLAMINES
SEROTONIN
HISTAMINE
MELATONIN
TESTIS
MALE INFERTILITY
AGING
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/280974
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/280974
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Biogenic amines in the testis: Sources, receptors and actionsFrungieri, Monica BeatrizMayerhofer, ArturCATECHOLAMINESSEROTONINHISTAMINEMELATONINTESTISMALE INFERTILITYAGINGhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Biogenic amines are signaling molecules with multiple roles in the centralnervous system and in peripheral organs, including the gonads. A series ofstudies indicated that these molecules, their biosynthetic enzymes and theirreceptors are present in the testis and that they are involved in the regulation ofmale reproductive physiology and/or pathology. This mini-review aims tosummarize the current knowledge in this field and to pinpoint existingresearch gaps. We suggest that the widespread clinical use of pharmacologicalagonists/antagonists of these signaling molecules, calls for new investigations inthis area. They are necessary to evaluate the relevance of biogenic amines forhuman male fertility and infertility, as well as the potential value of at least one ofthem as an anti-aging compound in the testis.Fil: Frungieri, Monica Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Mayerhofer, Artur. Ludwig Maximilians Universitat; AlemaniaFrontiers Media2024-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/280974Frungieri, Monica Beatriz; Mayerhofer, Artur; Biogenic amines in the testis: Sources, receptors and actions; Frontiers Media; Frontiers in Endocrinology; 15; 1392917; 6-2024; 1-21664-23921664-2392CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fendo.2024.1392917/fullinfo:eu-repo/semantics/altIdentifier/doi/10.3389/fendo.2024.1392917info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-02-26T09:58:43Zoai:ri.conicet.gov.ar:11336/280974instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-02-26 09:58:43.467CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Biogenic amines in the testis: Sources, receptors and actions
title Biogenic amines in the testis: Sources, receptors and actions
spellingShingle Biogenic amines in the testis: Sources, receptors and actions
Frungieri, Monica Beatriz
CATECHOLAMINES
SEROTONIN
HISTAMINE
MELATONIN
TESTIS
MALE INFERTILITY
AGING
title_short Biogenic amines in the testis: Sources, receptors and actions
title_full Biogenic amines in the testis: Sources, receptors and actions
title_fullStr Biogenic amines in the testis: Sources, receptors and actions
title_full_unstemmed Biogenic amines in the testis: Sources, receptors and actions
title_sort Biogenic amines in the testis: Sources, receptors and actions
dc.creator.none.fl_str_mv Frungieri, Monica Beatriz
Mayerhofer, Artur
author Frungieri, Monica Beatriz
author_facet Frungieri, Monica Beatriz
Mayerhofer, Artur
author_role author
author2 Mayerhofer, Artur
author2_role author
dc.subject.none.fl_str_mv CATECHOLAMINES
SEROTONIN
HISTAMINE
MELATONIN
TESTIS
MALE INFERTILITY
AGING
topic CATECHOLAMINES
SEROTONIN
HISTAMINE
MELATONIN
TESTIS
MALE INFERTILITY
AGING
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Biogenic amines are signaling molecules with multiple roles in the centralnervous system and in peripheral organs, including the gonads. A series ofstudies indicated that these molecules, their biosynthetic enzymes and theirreceptors are present in the testis and that they are involved in the regulation ofmale reproductive physiology and/or pathology. This mini-review aims tosummarize the current knowledge in this field and to pinpoint existingresearch gaps. We suggest that the widespread clinical use of pharmacologicalagonists/antagonists of these signaling molecules, calls for new investigations inthis area. They are necessary to evaluate the relevance of biogenic amines forhuman male fertility and infertility, as well as the potential value of at least one ofthem as an anti-aging compound in the testis.
Fil: Frungieri, Monica Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Mayerhofer, Artur. Ludwig Maximilians Universitat; Alemania
description Biogenic amines are signaling molecules with multiple roles in the centralnervous system and in peripheral organs, including the gonads. A series ofstudies indicated that these molecules, their biosynthetic enzymes and theirreceptors are present in the testis and that they are involved in the regulation ofmale reproductive physiology and/or pathology. This mini-review aims tosummarize the current knowledge in this field and to pinpoint existingresearch gaps. We suggest that the widespread clinical use of pharmacologicalagonists/antagonists of these signaling molecules, calls for new investigations inthis area. They are necessary to evaluate the relevance of biogenic amines forhuman male fertility and infertility, as well as the potential value of at least one ofthem as an anti-aging compound in the testis.
publishDate 2024
dc.date.none.fl_str_mv 2024-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/280974
Frungieri, Monica Beatriz; Mayerhofer, Artur; Biogenic amines in the testis: Sources, receptors and actions; Frontiers Media; Frontiers in Endocrinology; 15; 1392917; 6-2024; 1-2
1664-2392
1664-2392
CONICET Digital
CONICET
url http://hdl.handle.net/11336/280974
identifier_str_mv Frungieri, Monica Beatriz; Mayerhofer, Artur; Biogenic amines in the testis: Sources, receptors and actions; Frontiers Media; Frontiers in Endocrinology; 15; 1392917; 6-2024; 1-2
1664-2392
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fendo.2024.1392917/full
info:eu-repo/semantics/altIdentifier/doi/10.3389/fendo.2024.1392917
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.176822

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