Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer

Autores
Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; Cabrini, R.; Juvenal, Guillermo Juan; Pisarev, Mario Alberto
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.
Fil: Dagrosa, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Carpano, Marina. Comisión Nacional de Energía Atómica; Argentina
Fil: Perona, Marina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Thomasz, Lisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Nievas, S.. Comisión Nacional de Energía Atómica; Argentina
Fil: Cabrini, R.. Comisión Nacional de Energía Atómica; Argentina
Fil: Juvenal, Guillermo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
BPA
DIFFERENTIATED
THYROID CANCER
UPTAKE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/188595
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancerDagrosa, María AlejandraCarpano, MarinaPerona, MarinaThomasz, LisaNievas, S.Cabrini, R.Juvenal, Guillermo JuanPisarev, Mario AlbertoBPADIFFERENTIATEDTHYROID CANCERUPTAKEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.Fil: Dagrosa, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Carpano, Marina. Comisión Nacional de Energía Atómica; ArgentinaFil: Perona, Marina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Thomasz, Lisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Nievas, S.. Comisión Nacional de Energía Atómica; ArgentinaFil: Cabrini, R.. Comisión Nacional de Energía Atómica; ArgentinaFil: Juvenal, Guillermo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaPergamon-Elsevier Science Ltd2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/188595Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-17550969-8043CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0969804311001230info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2011.02.030info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:12:28Zoai:ri.conicet.gov.ar:11336/188595instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:12:28.356CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
title Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
spellingShingle Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
Dagrosa, María Alejandra
BPA
DIFFERENTIATED
THYROID CANCER
UPTAKE
title_short Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
title_full Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
title_fullStr Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
title_full_unstemmed Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
title_sort Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
dc.creator.none.fl_str_mv Dagrosa, María Alejandra
Carpano, Marina
Perona, Marina
Thomasz, Lisa
Nievas, S.
Cabrini, R.
Juvenal, Guillermo Juan
Pisarev, Mario Alberto
author Dagrosa, María Alejandra
author_facet Dagrosa, María Alejandra
Carpano, Marina
Perona, Marina
Thomasz, Lisa
Nievas, S.
Cabrini, R.
Juvenal, Guillermo Juan
Pisarev, Mario Alberto
author_role author
author2 Carpano, Marina
Perona, Marina
Thomasz, Lisa
Nievas, S.
Cabrini, R.
Juvenal, Guillermo Juan
Pisarev, Mario Alberto
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv BPA
DIFFERENTIATED
THYROID CANCER
UPTAKE
topic BPA
DIFFERENTIATED
THYROID CANCER
UPTAKE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.
Fil: Dagrosa, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Carpano, Marina. Comisión Nacional de Energía Atómica; Argentina
Fil: Perona, Marina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Thomasz, Lisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Nievas, S.. Comisión Nacional de Energía Atómica; Argentina
Fil: Cabrini, R.. Comisión Nacional de Energía Atómica; Argentina
Fil: Juvenal, Guillermo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/188595
Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-1755
0969-8043
CONICET Digital
CONICET
url http://hdl.handle.net/11336/188595
identifier_str_mv Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-1755
0969-8043
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0969804311001230
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2011.02.030
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614032115367936
score 13.069144

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