Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
- Autores
- Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; Cabrini, R.; Juvenal, Guillermo Juan; Pisarev, Mario Alberto
- Año de publicación
- 2011
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.
Fil: Dagrosa, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Carpano, Marina. Comisión Nacional de Energía Atómica; Argentina
Fil: Perona, Marina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Thomasz, Lisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Nievas, S.. Comisión Nacional de Energía Atómica; Argentina
Fil: Cabrini, R.. Comisión Nacional de Energía Atómica; Argentina
Fil: Juvenal, Guillermo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina - Materia
-
BPA
DIFFERENTIATED
THYROID CANCER
UPTAKE - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/188595
Ver los metadatos del registro completo
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Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancerDagrosa, María AlejandraCarpano, MarinaPerona, MarinaThomasz, LisaNievas, S.Cabrini, R.Juvenal, Guillermo JuanPisarev, Mario AlbertoBPADIFFERENTIATEDTHYROID CANCERUPTAKEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.Fil: Dagrosa, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Carpano, Marina. Comisión Nacional de Energía Atómica; ArgentinaFil: Perona, Marina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Thomasz, Lisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Nievas, S.. Comisión Nacional de Energía Atómica; ArgentinaFil: Cabrini, R.. Comisión Nacional de Energía Atómica; ArgentinaFil: Juvenal, Guillermo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaPergamon-Elsevier Science Ltd2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/188595Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-17550969-8043CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0969804311001230info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2011.02.030info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:00:33Zoai:ri.conicet.gov.ar:11336/188595instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:00:33.954CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
title |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
spellingShingle |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer Dagrosa, María Alejandra BPA DIFFERENTIATED THYROID CANCER UPTAKE |
title_short |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
title_full |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
title_fullStr |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
title_full_unstemmed |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
title_sort |
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer |
dc.creator.none.fl_str_mv |
Dagrosa, María Alejandra Carpano, Marina Perona, Marina Thomasz, Lisa Nievas, S. Cabrini, R. Juvenal, Guillermo Juan Pisarev, Mario Alberto |
author |
Dagrosa, María Alejandra |
author_facet |
Dagrosa, María Alejandra Carpano, Marina Perona, Marina Thomasz, Lisa Nievas, S. Cabrini, R. Juvenal, Guillermo Juan Pisarev, Mario Alberto |
author_role |
author |
author2 |
Carpano, Marina Perona, Marina Thomasz, Lisa Nievas, S. Cabrini, R. Juvenal, Guillermo Juan Pisarev, Mario Alberto |
author2_role |
author author author author author author author |
dc.subject.none.fl_str_mv |
BPA DIFFERENTIATED THYROID CANCER UPTAKE |
topic |
BPA DIFFERENTIATED THYROID CANCER UPTAKE |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor. Fil: Dagrosa, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina Fil: Carpano, Marina. Comisión Nacional de Energía Atómica; Argentina Fil: Perona, Marina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Thomasz, Lisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina Fil: Nievas, S.. Comisión Nacional de Energía Atómica; Argentina Fil: Cabrini, R.. Comisión Nacional de Energía Atómica; Argentina Fil: Juvenal, Guillermo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina Fil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina |
description |
The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-12 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/188595 Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-1755 0969-8043 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/188595 |
identifier_str_mv |
Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-1755 0969-8043 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0969804311001230 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2011.02.030 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Pergamon-Elsevier Science Ltd |
publisher.none.fl_str_mv |
Pergamon-Elsevier Science Ltd |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842269645951729664 |
score |
13.13397 |