Arabidopsis α Aurora kinases function in formative cell division plane orientation

Autores
van Damme, Daniël; de Rybel, Bert; Gudesblat, Gustavo Eduardo; Demidov, Dmitri; Grunewald, Wim; de Smet, Ive; Houben, Andreas; Beeckman, Tom; Russinova, Eugenia
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
To establish three-dimensional structures/organs, plant cells continuously have to adapt the orientation of their division plane in a highly regulated manner. However, mechanisms underlying switches in division plane orientation remain elusive. Here, we characterize a viable double knockdown mutant in Arabidopsis thaliana group a Aurora (AUR) kinases, AUR1 and AUR2, (aur1-2 aur2-2), with a primary defect in lateral root formation and outgrowth. Mutant analysis revealed that aur1-2 aur2-2 lateral root primordia are built from randomly oriented cell divisions instead of distinct cell layers. This phenotype could be traced back to cytokinesis defects and misoriented cell plates during the initial anticlinal pericycle cell divisions that give rise to lateral root primordia. Complementation assays showed that the Arabidopsis a group Aurora kinases are functionally divergent from the single b group member AUR3 and that AUR1 functions in division plane orientation prior to cytokinesis. In addition to defective lateral root patterning, aur1-2 aur2-2 plants also show defects in orienting formative divisions during embryogenesis, divisions surrounding the main root stem cell niche, and divisions surrounding stomata formation. Taken together, our results put forward a central role for a Aurora kinases in regulating formative division plane orientation throughout development.
Fil: van Damme, Daniël. University of Ghent; Bélgica
Fil: de Rybel, Bert. University of Ghent; Bélgica
Fil: Gudesblat, Gustavo Eduardo. University of Ghent; Bélgica. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología "Dr. César Milstein". Fundación Pablo Cassará. Instituto de Ciencia y Tecnología "Dr. César Milstein"; Argentina
Fil: Demidov, Dmitri. Leibniz Institute of Plant Genetics and Crop Plant Research; Alemania
Fil: Grunewald, Wim. University of Ghent; Bélgica
Fil: de Smet, Ive. University of Nottingham; Reino Unido
Fil: Houben, Andreas. Leibniz Institute of Plant Genetics and Crop Plant Research; Alemania
Fil: Beeckman, Tom. University of Ghent; Bélgica
Fil: Russinova, Eugenia. University of Ghent; Bélgica
Materia
Cell Division
Root Development
Aurora Kinase
Stomata
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/68969
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/68969
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Arabidopsis α Aurora kinases function in formative cell division plane orientationvan Damme, Daniëlde Rybel, BertGudesblat, Gustavo EduardoDemidov, DmitriGrunewald, Wimde Smet, IveHouben, AndreasBeeckman, TomRussinova, EugeniaCell DivisionRoot DevelopmentAurora KinaseStomatahttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1To establish three-dimensional structures/organs, plant cells continuously have to adapt the orientation of their division plane in a highly regulated manner. However, mechanisms underlying switches in division plane orientation remain elusive. Here, we characterize a viable double knockdown mutant in Arabidopsis thaliana group a Aurora (AUR) kinases, AUR1 and AUR2, (aur1-2 aur2-2), with a primary defect in lateral root formation and outgrowth. Mutant analysis revealed that aur1-2 aur2-2 lateral root primordia are built from randomly oriented cell divisions instead of distinct cell layers. This phenotype could be traced back to cytokinesis defects and misoriented cell plates during the initial anticlinal pericycle cell divisions that give rise to lateral root primordia. Complementation assays showed that the Arabidopsis a group Aurora kinases are functionally divergent from the single b group member AUR3 and that AUR1 functions in division plane orientation prior to cytokinesis. In addition to defective lateral root patterning, aur1-2 aur2-2 plants also show defects in orienting formative divisions during embryogenesis, divisions surrounding the main root stem cell niche, and divisions surrounding stomata formation. Taken together, our results put forward a central role for a Aurora kinases in regulating formative division plane orientation throughout development.Fil: van Damme, Daniël. University of Ghent; BélgicaFil: de Rybel, Bert. University of Ghent; BélgicaFil: Gudesblat, Gustavo Eduardo. University of Ghent; Bélgica. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología "Dr. César Milstein". Fundación Pablo Cassará. Instituto de Ciencia y Tecnología "Dr. César Milstein"; ArgentinaFil: Demidov, Dmitri. Leibniz Institute of Plant Genetics and Crop Plant Research; AlemaniaFil: Grunewald, Wim. University of Ghent; BélgicaFil: de Smet, Ive. University of Nottingham; Reino UnidoFil: Houben, Andreas. Leibniz Institute of Plant Genetics and Crop Plant Research; AlemaniaFil: Beeckman, Tom. University of Ghent; BélgicaFil: Russinova, Eugenia. University of Ghent; BélgicaAmerican Society of Plant Biologist2011-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/68969van Damme, Daniël; de Rybel, Bert; Gudesblat, Gustavo Eduardo; Demidov, Dmitri; Grunewald, Wim; et al.; Arabidopsis α Aurora kinases function in formative cell division plane orientation; American Society of Plant Biologist; Plant Cell; 23; 11; 11-2011; 4013-40241040-4651CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.plantcell.org/content/23/11/4013.abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1105/tpc.111.089565info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:12:58Zoai:ri.conicet.gov.ar:11336/68969instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:12:58.724CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Arabidopsis α Aurora kinases function in formative cell division plane orientation
title Arabidopsis α Aurora kinases function in formative cell division plane orientation
spellingShingle Arabidopsis α Aurora kinases function in formative cell division plane orientation
van Damme, Daniël
Cell Division
Root Development
Aurora Kinase
Stomata
title_short Arabidopsis α Aurora kinases function in formative cell division plane orientation
title_full Arabidopsis α Aurora kinases function in formative cell division plane orientation
title_fullStr Arabidopsis α Aurora kinases function in formative cell division plane orientation
title_full_unstemmed Arabidopsis α Aurora kinases function in formative cell division plane orientation
title_sort Arabidopsis α Aurora kinases function in formative cell division plane orientation
dc.creator.none.fl_str_mv van Damme, Daniël
de Rybel, Bert
Gudesblat, Gustavo Eduardo
Demidov, Dmitri
Grunewald, Wim
de Smet, Ive
Houben, Andreas
Beeckman, Tom
Russinova, Eugenia
author van Damme, Daniël
author_facet van Damme, Daniël
de Rybel, Bert
Gudesblat, Gustavo Eduardo
Demidov, Dmitri
Grunewald, Wim
de Smet, Ive
Houben, Andreas
Beeckman, Tom
Russinova, Eugenia
author_role author
author2 de Rybel, Bert
Gudesblat, Gustavo Eduardo
Demidov, Dmitri
Grunewald, Wim
de Smet, Ive
Houben, Andreas
Beeckman, Tom
Russinova, Eugenia
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Cell Division
Root Development
Aurora Kinase
Stomata
topic Cell Division
Root Development
Aurora Kinase
Stomata
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv To establish three-dimensional structures/organs, plant cells continuously have to adapt the orientation of their division plane in a highly regulated manner. However, mechanisms underlying switches in division plane orientation remain elusive. Here, we characterize a viable double knockdown mutant in Arabidopsis thaliana group a Aurora (AUR) kinases, AUR1 and AUR2, (aur1-2 aur2-2), with a primary defect in lateral root formation and outgrowth. Mutant analysis revealed that aur1-2 aur2-2 lateral root primordia are built from randomly oriented cell divisions instead of distinct cell layers. This phenotype could be traced back to cytokinesis defects and misoriented cell plates during the initial anticlinal pericycle cell divisions that give rise to lateral root primordia. Complementation assays showed that the Arabidopsis a group Aurora kinases are functionally divergent from the single b group member AUR3 and that AUR1 functions in division plane orientation prior to cytokinesis. In addition to defective lateral root patterning, aur1-2 aur2-2 plants also show defects in orienting formative divisions during embryogenesis, divisions surrounding the main root stem cell niche, and divisions surrounding stomata formation. Taken together, our results put forward a central role for a Aurora kinases in regulating formative division plane orientation throughout development.
Fil: van Damme, Daniël. University of Ghent; Bélgica
Fil: de Rybel, Bert. University of Ghent; Bélgica
Fil: Gudesblat, Gustavo Eduardo. University of Ghent; Bélgica. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología "Dr. César Milstein". Fundación Pablo Cassará. Instituto de Ciencia y Tecnología "Dr. César Milstein"; Argentina
Fil: Demidov, Dmitri. Leibniz Institute of Plant Genetics and Crop Plant Research; Alemania
Fil: Grunewald, Wim. University of Ghent; Bélgica
Fil: de Smet, Ive. University of Nottingham; Reino Unido
Fil: Houben, Andreas. Leibniz Institute of Plant Genetics and Crop Plant Research; Alemania
Fil: Beeckman, Tom. University of Ghent; Bélgica
Fil: Russinova, Eugenia. University of Ghent; Bélgica
description To establish three-dimensional structures/organs, plant cells continuously have to adapt the orientation of their division plane in a highly regulated manner. However, mechanisms underlying switches in division plane orientation remain elusive. Here, we characterize a viable double knockdown mutant in Arabidopsis thaliana group a Aurora (AUR) kinases, AUR1 and AUR2, (aur1-2 aur2-2), with a primary defect in lateral root formation and outgrowth. Mutant analysis revealed that aur1-2 aur2-2 lateral root primordia are built from randomly oriented cell divisions instead of distinct cell layers. This phenotype could be traced back to cytokinesis defects and misoriented cell plates during the initial anticlinal pericycle cell divisions that give rise to lateral root primordia. Complementation assays showed that the Arabidopsis a group Aurora kinases are functionally divergent from the single b group member AUR3 and that AUR1 functions in division plane orientation prior to cytokinesis. In addition to defective lateral root patterning, aur1-2 aur2-2 plants also show defects in orienting formative divisions during embryogenesis, divisions surrounding the main root stem cell niche, and divisions surrounding stomata formation. Taken together, our results put forward a central role for a Aurora kinases in regulating formative division plane orientation throughout development.
publishDate 2011
dc.date.none.fl_str_mv 2011-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/68969
van Damme, Daniël; de Rybel, Bert; Gudesblat, Gustavo Eduardo; Demidov, Dmitri; Grunewald, Wim; et al.; Arabidopsis α Aurora kinases function in formative cell division plane orientation; American Society of Plant Biologist; Plant Cell; 23; 11; 11-2011; 4013-4024
1040-4651
CONICET Digital
CONICET
url http://hdl.handle.net/11336/68969
identifier_str_mv van Damme, Daniël; de Rybel, Bert; Gudesblat, Gustavo Eduardo; Demidov, Dmitri; Grunewald, Wim; et al.; Arabidopsis α Aurora kinases function in formative cell division plane orientation; American Society of Plant Biologist; Plant Cell; 23; 11; 11-2011; 4013-4024
1040-4651
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.plantcell.org/content/23/11/4013.abstract
info:eu-repo/semantics/altIdentifier/doi/10.1105/tpc.111.089565
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Society of Plant Biologist
publisher.none.fl_str_mv American Society of Plant Biologist
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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