Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity
- Autores
- Belelli, Patricia Gabriela; Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Ferullo, Ricardo; Di Cosimo, Juana Isabel
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The liquid-phase MgO-promoted glycerolysis of methyl oleate, a fatty acid methyl ester (FAME), to give acylglycerol products was studied both, experimentally and by density functional theory (DFT). Catalytic results showed that strongly basic low coordination O2− surface sites participate in kinetically relevant steps of the glycerolysis reaction. Changes in the selectivity toward the different mono- and diglyceride isomers were investigated by varying the reaction conditions. The main product was always α-glyceryl monooleate (α-MG), a monoglyceride with the ester fragment at one of the terminal positions of the glycerol molecule; the β-MG isomer, with the ester substituted at position 2 was obtained in much lower amounts. The molecular modeling of glycerol (Gly) and FAME adsorptions as well as of the glycerolysis reaction was carried out using periodic DFT calculations and a model of stepped MgO surface. Results indicated that FAME was more weakly adsorbed than Gly; the latter adsorbs on a coordinatively unsaturated surface O2− site with Osingle bondH bond breaking at position 2 of the Gly molecule, giving therefore a surface β-glyceroxide species. Calculations explained the apparent contradiction between the preferential formation of the α-MG isomer and the energetically favored dissociation of the secondary OH group of Gly that leads to the β-glyceroxide species. They predict that the β-glyceroxide species participates in the pathways conducting to both, α- and β-MG isomers. Synthesis of α-MG occurs by Csingle bondO coupling of β-glyceroxide with FAME at one of the two primary OH groups of the β-glyceroxide species. Two transition states (TS) and a tetrahedral intermediate (TI) are involved in both, α-MG and β-MG isomer formation. However, the pathway toward β-MG is limited by the large sterical effects associated to the TI formation. Contrarily, the TI leading to α-MG is relatively easy to form.
Fil: Belelli, Patricia Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Física del Sur; Argentina
Fil: Ferretti, Cristián Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; Argentina
Fil: Apesteguia, Carlos Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; Argentina
Fil: Ferullo, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Di Cosimo, Juana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; Argentina - Materia
-
Mgo
Fatty Acid
Glycerolysis
Dft - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/6534
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Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivityBelelli, Patricia GabrielaFerretti, Cristián AlejandroApesteguia, Carlos RodolfoFerullo, RicardoDi Cosimo, Juana IsabelMgoFatty AcidGlycerolysisDfthttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The liquid-phase MgO-promoted glycerolysis of methyl oleate, a fatty acid methyl ester (FAME), to give acylglycerol products was studied both, experimentally and by density functional theory (DFT). Catalytic results showed that strongly basic low coordination O2− surface sites participate in kinetically relevant steps of the glycerolysis reaction. Changes in the selectivity toward the different mono- and diglyceride isomers were investigated by varying the reaction conditions. The main product was always α-glyceryl monooleate (α-MG), a monoglyceride with the ester fragment at one of the terminal positions of the glycerol molecule; the β-MG isomer, with the ester substituted at position 2 was obtained in much lower amounts. The molecular modeling of glycerol (Gly) and FAME adsorptions as well as of the glycerolysis reaction was carried out using periodic DFT calculations and a model of stepped MgO surface. Results indicated that FAME was more weakly adsorbed than Gly; the latter adsorbs on a coordinatively unsaturated surface O2− site with Osingle bondH bond breaking at position 2 of the Gly molecule, giving therefore a surface β-glyceroxide species. Calculations explained the apparent contradiction between the preferential formation of the α-MG isomer and the energetically favored dissociation of the secondary OH group of Gly that leads to the β-glyceroxide species. They predict that the β-glyceroxide species participates in the pathways conducting to both, α- and β-MG isomers. Synthesis of α-MG occurs by Csingle bondO coupling of β-glyceroxide with FAME at one of the two primary OH groups of the β-glyceroxide species. Two transition states (TS) and a tetrahedral intermediate (TI) are involved in both, α-MG and β-MG isomer formation. However, the pathway toward β-MG is limited by the large sterical effects associated to the TI formation. Contrarily, the TI leading to α-MG is relatively easy to form.Fil: Belelli, Patricia Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Física del Sur; ArgentinaFil: Ferretti, Cristián Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; ArgentinaFil: Apesteguia, Carlos Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; ArgentinaFil: Ferullo, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; ArgentinaFil: Di Cosimo, Juana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; ArgentinaElsevier2015-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/6534Belelli, Patricia Gabriela; Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Ferullo, Ricardo; Di Cosimo, Juana Isabel; Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity; Elsevier; Journal of Catalysis; 323; 1-2015; 132-1440021-9517enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0021951715000032info:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jcat.2015.01.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:57:14Zoai:ri.conicet.gov.ar:11336/6534instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:14.45CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
title |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
spellingShingle |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity Belelli, Patricia Gabriela Mgo Fatty Acid Glycerolysis Dft |
title_short |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
title_full |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
title_fullStr |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
title_full_unstemmed |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
title_sort |
Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity |
dc.creator.none.fl_str_mv |
Belelli, Patricia Gabriela Ferretti, Cristián Alejandro Apesteguia, Carlos Rodolfo Ferullo, Ricardo Di Cosimo, Juana Isabel |
author |
Belelli, Patricia Gabriela |
author_facet |
Belelli, Patricia Gabriela Ferretti, Cristián Alejandro Apesteguia, Carlos Rodolfo Ferullo, Ricardo Di Cosimo, Juana Isabel |
author_role |
author |
author2 |
Ferretti, Cristián Alejandro Apesteguia, Carlos Rodolfo Ferullo, Ricardo Di Cosimo, Juana Isabel |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
Mgo Fatty Acid Glycerolysis Dft |
topic |
Mgo Fatty Acid Glycerolysis Dft |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
The liquid-phase MgO-promoted glycerolysis of methyl oleate, a fatty acid methyl ester (FAME), to give acylglycerol products was studied both, experimentally and by density functional theory (DFT). Catalytic results showed that strongly basic low coordination O2− surface sites participate in kinetically relevant steps of the glycerolysis reaction. Changes in the selectivity toward the different mono- and diglyceride isomers were investigated by varying the reaction conditions. The main product was always α-glyceryl monooleate (α-MG), a monoglyceride with the ester fragment at one of the terminal positions of the glycerol molecule; the β-MG isomer, with the ester substituted at position 2 was obtained in much lower amounts. The molecular modeling of glycerol (Gly) and FAME adsorptions as well as of the glycerolysis reaction was carried out using periodic DFT calculations and a model of stepped MgO surface. Results indicated that FAME was more weakly adsorbed than Gly; the latter adsorbs on a coordinatively unsaturated surface O2− site with Osingle bondH bond breaking at position 2 of the Gly molecule, giving therefore a surface β-glyceroxide species. Calculations explained the apparent contradiction between the preferential formation of the α-MG isomer and the energetically favored dissociation of the secondary OH group of Gly that leads to the β-glyceroxide species. They predict that the β-glyceroxide species participates in the pathways conducting to both, α- and β-MG isomers. Synthesis of α-MG occurs by Csingle bondO coupling of β-glyceroxide with FAME at one of the two primary OH groups of the β-glyceroxide species. Two transition states (TS) and a tetrahedral intermediate (TI) are involved in both, α-MG and β-MG isomer formation. However, the pathway toward β-MG is limited by the large sterical effects associated to the TI formation. Contrarily, the TI leading to α-MG is relatively easy to form. Fil: Belelli, Patricia Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Física del Sur; Argentina Fil: Ferretti, Cristián Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; Argentina Fil: Apesteguia, Carlos Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; Argentina Fil: Ferullo, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina Fil: Di Cosimo, Juana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica; Argentina |
description |
The liquid-phase MgO-promoted glycerolysis of methyl oleate, a fatty acid methyl ester (FAME), to give acylglycerol products was studied both, experimentally and by density functional theory (DFT). Catalytic results showed that strongly basic low coordination O2− surface sites participate in kinetically relevant steps of the glycerolysis reaction. Changes in the selectivity toward the different mono- and diglyceride isomers were investigated by varying the reaction conditions. The main product was always α-glyceryl monooleate (α-MG), a monoglyceride with the ester fragment at one of the terminal positions of the glycerol molecule; the β-MG isomer, with the ester substituted at position 2 was obtained in much lower amounts. The molecular modeling of glycerol (Gly) and FAME adsorptions as well as of the glycerolysis reaction was carried out using periodic DFT calculations and a model of stepped MgO surface. Results indicated that FAME was more weakly adsorbed than Gly; the latter adsorbs on a coordinatively unsaturated surface O2− site with Osingle bondH bond breaking at position 2 of the Gly molecule, giving therefore a surface β-glyceroxide species. Calculations explained the apparent contradiction between the preferential formation of the α-MG isomer and the energetically favored dissociation of the secondary OH group of Gly that leads to the β-glyceroxide species. They predict that the β-glyceroxide species participates in the pathways conducting to both, α- and β-MG isomers. Synthesis of α-MG occurs by Csingle bondO coupling of β-glyceroxide with FAME at one of the two primary OH groups of the β-glyceroxide species. Two transition states (TS) and a tetrahedral intermediate (TI) are involved in both, α-MG and β-MG isomer formation. However, the pathway toward β-MG is limited by the large sterical effects associated to the TI formation. Contrarily, the TI leading to α-MG is relatively easy to form. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-01 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/6534 Belelli, Patricia Gabriela; Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Ferullo, Ricardo; Di Cosimo, Juana Isabel; Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity; Elsevier; Journal of Catalysis; 323; 1-2015; 132-144 0021-9517 |
url |
http://hdl.handle.net/11336/6534 |
identifier_str_mv |
Belelli, Patricia Gabriela; Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Ferullo, Ricardo; Di Cosimo, Juana Isabel; Glycerolysis of methyl oleate on MgO: experimental and theoretical study of the reaction selectivity; Elsevier; Journal of Catalysis; 323; 1-2015; 132-144 0021-9517 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0021951715000032 info:eu-repo/semantics/altIdentifier/doi/ info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jcat.2015.01.001 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613713288495104 |
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13.070432 |