The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age

Autores
Abecia, J. A.; Casao, A.; Pascual-Alonso, M.; Lobón, S.; Aguayo-Ulloa, L. A.; Meikle, A.; Forcada, F.; Sosa, C.; Marin, Raul Hector; Silva, M. A.; Maria, G. A.
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Maternal periconceptional undernutrition is associated with altered development and increased risks of adverse outcomes in the offspring. This circumstance is normal in flocks under extensive farming systems, which depend on natural forage resources. The aim of this study was to determine the effect of periconceptional undernutrition in sheep on behavioral and reproductive aspects of the offspring. Eighty ewes were synchronized in estrus and allocated to two groups (n=40) to be fed diets that provided 1.5 (C) or 0.5 (L) times the requirements for maintenance. Ewes were mated and 7 days later fed the control diet until lambing. One month after lambing, 32 lambs were exposed to tests to determine their cognitive and emotional responses. Six ewe lambs were euthanized and in vitro maturation and fertilization procedures were performed. L ewes presented a significant reduction in prolificacy and fecundity (P<0.05) in comparison with C ewes. Mean LW at lambing of L lambs was significantly higher than C lambs (C: 3.80±0.11; L: 4.24±0.15 kg, P<0.05). Lambs born from C ewes spent more time walking than L lambs (P<0.05) in the isolation test, revealing a decrease in the locomotor activity of lambs born from undernourished ewes around conception. Ewe lambs from the undernourished ewes presented a total population of oocytes 2.3 times higher than ovaries from control ewe lambs (60.0±7.8 v. 140.0±18.5 oocytes; P<0.05). In conclusion, periconceptional undernutrition is able to produce an increment in the body weight and the oocyte population, and an alteration of the locomotor activity of the offspring.
Fil: Abecia, J. A.. Universidad de Zaragoza; España
Fil: Casao, A.. Universidad de Zaragoza; España
Fil: Pascual-Alonso, M.. Universidad de Zaragoza; España
Fil: Lobón, S.. Universidad de Zaragoza; España
Fil: Aguayo-Ulloa, L. A.. Universidad de Zaragoza; España
Fil: Meikle, A.. Universidad de la Republica; Uruguay
Fil: Forcada, F.. Universidad de Zaragoza; España
Fil: Sosa, C.. Universidad de Zaragoza; España
Fil: Marin, Raul Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
Fil: Silva, M. A.. Universidad de Zaragoza; España
Fil: Maria, G. A.. Universidad de Zaragoza; España
Materia
Offspring
Periconceptional
Sheep
Undernutrition
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/76788
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/76788
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of ageAbecia, J. A.Casao, A.Pascual-Alonso, M.Lobón, S.Aguayo-Ulloa, L. A.Meikle, A.Forcada, F.Sosa, C.Marin, Raul HectorSilva, M. A.Maria, G. A.OffspringPericonceptionalSheepUndernutritionhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Maternal periconceptional undernutrition is associated with altered development and increased risks of adverse outcomes in the offspring. This circumstance is normal in flocks under extensive farming systems, which depend on natural forage resources. The aim of this study was to determine the effect of periconceptional undernutrition in sheep on behavioral and reproductive aspects of the offspring. Eighty ewes were synchronized in estrus and allocated to two groups (n=40) to be fed diets that provided 1.5 (C) or 0.5 (L) times the requirements for maintenance. Ewes were mated and 7 days later fed the control diet until lambing. One month after lambing, 32 lambs were exposed to tests to determine their cognitive and emotional responses. Six ewe lambs were euthanized and in vitro maturation and fertilization procedures were performed. L ewes presented a significant reduction in prolificacy and fecundity (P<0.05) in comparison with C ewes. Mean LW at lambing of L lambs was significantly higher than C lambs (C: 3.80±0.11; L: 4.24±0.15 kg, P<0.05). Lambs born from C ewes spent more time walking than L lambs (P<0.05) in the isolation test, revealing a decrease in the locomotor activity of lambs born from undernourished ewes around conception. Ewe lambs from the undernourished ewes presented a total population of oocytes 2.3 times higher than ovaries from control ewe lambs (60.0±7.8 v. 140.0±18.5 oocytes; P<0.05). In conclusion, periconceptional undernutrition is able to produce an increment in the body weight and the oocyte population, and an alteration of the locomotor activity of the offspring.Fil: Abecia, J. A.. Universidad de Zaragoza; EspañaFil: Casao, A.. Universidad de Zaragoza; EspañaFil: Pascual-Alonso, M.. Universidad de Zaragoza; EspañaFil: Lobón, S.. Universidad de Zaragoza; EspañaFil: Aguayo-Ulloa, L. A.. Universidad de Zaragoza; EspañaFil: Meikle, A.. Universidad de la Republica; UruguayFil: Forcada, F.. Universidad de Zaragoza; EspañaFil: Sosa, C.. Universidad de Zaragoza; EspañaFil: Marin, Raul Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; ArgentinaFil: Silva, M. A.. Universidad de Zaragoza; EspañaFil: Maria, G. A.. Universidad de Zaragoza; EspañaCambridge University Press2014-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/76788Abecia, J. A.; Casao, A.; Pascual-Alonso, M.; Lobón, S.; Aguayo-Ulloa, L. A.; et al.; The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age; Cambridge University Press; Journal of Developmental Origins of Health and Disease; 5; 2; 10-2014; 79-872040-17522040-1744CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/24847694info:eu-repo/semantics/altIdentifier/doi/10.1017/S2040174414000051info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:54:43Zoai:ri.conicet.gov.ar:11336/76788instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:54:43.843CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
title The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
spellingShingle The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
Abecia, J. A.
Offspring
Periconceptional
Sheep
Undernutrition
title_short The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
title_full The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
title_fullStr The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
title_full_unstemmed The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
title_sort The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age
dc.creator.none.fl_str_mv Abecia, J. A.
Casao, A.
Pascual-Alonso, M.
Lobón, S.
Aguayo-Ulloa, L. A.
Meikle, A.
Forcada, F.
Sosa, C.
Marin, Raul Hector
Silva, M. A.
Maria, G. A.
author Abecia, J. A.
author_facet Abecia, J. A.
Casao, A.
Pascual-Alonso, M.
Lobón, S.
Aguayo-Ulloa, L. A.
Meikle, A.
Forcada, F.
Sosa, C.
Marin, Raul Hector
Silva, M. A.
Maria, G. A.
author_role author
author2 Casao, A.
Pascual-Alonso, M.
Lobón, S.
Aguayo-Ulloa, L. A.
Meikle, A.
Forcada, F.
Sosa, C.
Marin, Raul Hector
Silva, M. A.
Maria, G. A.
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Offspring
Periconceptional
Sheep
Undernutrition
topic Offspring
Periconceptional
Sheep
Undernutrition
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Maternal periconceptional undernutrition is associated with altered development and increased risks of adverse outcomes in the offspring. This circumstance is normal in flocks under extensive farming systems, which depend on natural forage resources. The aim of this study was to determine the effect of periconceptional undernutrition in sheep on behavioral and reproductive aspects of the offspring. Eighty ewes were synchronized in estrus and allocated to two groups (n=40) to be fed diets that provided 1.5 (C) or 0.5 (L) times the requirements for maintenance. Ewes were mated and 7 days later fed the control diet until lambing. One month after lambing, 32 lambs were exposed to tests to determine their cognitive and emotional responses. Six ewe lambs were euthanized and in vitro maturation and fertilization procedures were performed. L ewes presented a significant reduction in prolificacy and fecundity (P<0.05) in comparison with C ewes. Mean LW at lambing of L lambs was significantly higher than C lambs (C: 3.80±0.11; L: 4.24±0.15 kg, P<0.05). Lambs born from C ewes spent more time walking than L lambs (P<0.05) in the isolation test, revealing a decrease in the locomotor activity of lambs born from undernourished ewes around conception. Ewe lambs from the undernourished ewes presented a total population of oocytes 2.3 times higher than ovaries from control ewe lambs (60.0±7.8 v. 140.0±18.5 oocytes; P<0.05). In conclusion, periconceptional undernutrition is able to produce an increment in the body weight and the oocyte population, and an alteration of the locomotor activity of the offspring.
Fil: Abecia, J. A.. Universidad de Zaragoza; España
Fil: Casao, A.. Universidad de Zaragoza; España
Fil: Pascual-Alonso, M.. Universidad de Zaragoza; España
Fil: Lobón, S.. Universidad de Zaragoza; España
Fil: Aguayo-Ulloa, L. A.. Universidad de Zaragoza; España
Fil: Meikle, A.. Universidad de la Republica; Uruguay
Fil: Forcada, F.. Universidad de Zaragoza; España
Fil: Sosa, C.. Universidad de Zaragoza; España
Fil: Marin, Raul Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
Fil: Silva, M. A.. Universidad de Zaragoza; España
Fil: Maria, G. A.. Universidad de Zaragoza; España
description Maternal periconceptional undernutrition is associated with altered development and increased risks of adverse outcomes in the offspring. This circumstance is normal in flocks under extensive farming systems, which depend on natural forage resources. The aim of this study was to determine the effect of periconceptional undernutrition in sheep on behavioral and reproductive aspects of the offspring. Eighty ewes were synchronized in estrus and allocated to two groups (n=40) to be fed diets that provided 1.5 (C) or 0.5 (L) times the requirements for maintenance. Ewes were mated and 7 days later fed the control diet until lambing. One month after lambing, 32 lambs were exposed to tests to determine their cognitive and emotional responses. Six ewe lambs were euthanized and in vitro maturation and fertilization procedures were performed. L ewes presented a significant reduction in prolificacy and fecundity (P<0.05) in comparison with C ewes. Mean LW at lambing of L lambs was significantly higher than C lambs (C: 3.80±0.11; L: 4.24±0.15 kg, P<0.05). Lambs born from C ewes spent more time walking than L lambs (P<0.05) in the isolation test, revealing a decrease in the locomotor activity of lambs born from undernourished ewes around conception. Ewe lambs from the undernourished ewes presented a total population of oocytes 2.3 times higher than ovaries from control ewe lambs (60.0±7.8 v. 140.0±18.5 oocytes; P<0.05). In conclusion, periconceptional undernutrition is able to produce an increment in the body weight and the oocyte population, and an alteration of the locomotor activity of the offspring.
publishDate 2014
dc.date.none.fl_str_mv 2014-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/76788
Abecia, J. A.; Casao, A.; Pascual-Alonso, M.; Lobón, S.; Aguayo-Ulloa, L. A.; et al.; The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age; Cambridge University Press; Journal of Developmental Origins of Health and Disease; 5; 2; 10-2014; 79-87
2040-1752
2040-1744
CONICET Digital
CONICET
url http://hdl.handle.net/11336/76788
identifier_str_mv Abecia, J. A.; Casao, A.; Pascual-Alonso, M.; Lobón, S.; Aguayo-Ulloa, L. A.; et al.; The effect of periconceptional undernutrition of sheep on the cognitive/emotional response and oocyte quality of offspring at 30 days of age; Cambridge University Press; Journal of Developmental Origins of Health and Disease; 5; 2; 10-2014; 79-87
2040-1752
2040-1744
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/24847694
info:eu-repo/semantics/altIdentifier/doi/10.1017/S2040174414000051
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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