Effect of undernutrition on the cranial growth of the rat: An intergenerational study

Autores
Cesani Rossi, María Florencia; Orden, Alicia Bibiana; Zucchi, Mariel; Muñe, Maria Cristina; Oyhenart, Evelia Edith; Pucciarelli, Hector Mario
Año de publicación
2003
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The cumulative effect of undernutrition on successive generations was tested. The cranial growth of three generations of undernourished rats (F1, F2, F3) was compared to that of the parental generation (P), in order to (1) measure the extent to which the growth of each facial and neurocranial functional component was retarded when animals were undernourished and (2) determine whether any cumulative effect between generations can be found. The P generation was fed ad libitum, and the undernourished generations were fed 50% (F1) and 75% (F2 and F3) of the parental diet. Nine radiographs were taken from the age of 20-100 days. The length, width and height of the neurocranial and facial components were measured on each radiograph. Neurocranial (VNI), facial (VFI), and neurofacial (NFI) indices were calculated. Data were processed by the Kruskal-Wallis and Kolmogorov-Smirnov tests. An impairment in neurocranial and facial growth was found, the latter being more affected than the former in F1. At variance, the neurocranium was more affected than the face in F2 and F3, resulting in variations of the shape of the skull. A cumulative effect of moderate transgenerational undernutrition was evident and points to the need for further analysis on this topic. Copyright © 2003 S. Karger AG, Basel.
Fil: Cesani Rossi, María Florencia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
Fil: Orden, Alicia Bibiana. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
Fil: Zucchi, Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Fil: Muñe, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Fil: Oyhenart, Evelia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Fil: Pucciarelli, Hector Mario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Materia
Rat
Skull Growth
Transgenerational Undernutrition
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/83711
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Effect of undernutrition on the cranial growth of the rat: An intergenerational studyCesani Rossi, María FlorenciaOrden, Alicia BibianaZucchi, MarielMuñe, Maria CristinaOyhenart, Evelia EdithPucciarelli, Hector MarioRatSkull GrowthTransgenerational Undernutritionhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3The cumulative effect of undernutrition on successive generations was tested. The cranial growth of three generations of undernourished rats (F1, F2, F3) was compared to that of the parental generation (P), in order to (1) measure the extent to which the growth of each facial and neurocranial functional component was retarded when animals were undernourished and (2) determine whether any cumulative effect between generations can be found. The P generation was fed ad libitum, and the undernourished generations were fed 50% (F1) and 75% (F2 and F3) of the parental diet. Nine radiographs were taken from the age of 20-100 days. The length, width and height of the neurocranial and facial components were measured on each radiograph. Neurocranial (VNI), facial (VFI), and neurofacial (NFI) indices were calculated. Data were processed by the Kruskal-Wallis and Kolmogorov-Smirnov tests. An impairment in neurocranial and facial growth was found, the latter being more affected than the former in F1. At variance, the neurocranium was more affected than the face in F2 and F3, resulting in variations of the shape of the skull. A cumulative effect of moderate transgenerational undernutrition was evident and points to the need for further analysis on this topic. Copyright © 2003 S. Karger AG, Basel.Fil: Cesani Rossi, María Florencia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; ArgentinaFil: Orden, Alicia Bibiana. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; ArgentinaFil: Zucchi, Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; ArgentinaFil: Muñe, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; ArgentinaFil: Oyhenart, Evelia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; ArgentinaFil: Pucciarelli, Hector Mario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; ArgentinaKarger2003-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/83711Cesani Rossi, María Florencia; Orden, Alicia Bibiana; Zucchi, Mariel; Muñe, Maria Cristina; Oyhenart, Evelia Edith; et al.; Effect of undernutrition on the cranial growth of the rat: An intergenerational study; Karger; Cells Tissues Organs; 174; 3; 12-2003; 129-1351422-6405CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1159/000071153info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/71153info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:33:55Zoai:ri.conicet.gov.ar:11336/83711instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:33:56.034CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effect of undernutrition on the cranial growth of the rat: An intergenerational study
title Effect of undernutrition on the cranial growth of the rat: An intergenerational study
spellingShingle Effect of undernutrition on the cranial growth of the rat: An intergenerational study
Cesani Rossi, María Florencia
Rat
Skull Growth
Transgenerational Undernutrition
title_short Effect of undernutrition on the cranial growth of the rat: An intergenerational study
title_full Effect of undernutrition on the cranial growth of the rat: An intergenerational study
title_fullStr Effect of undernutrition on the cranial growth of the rat: An intergenerational study
title_full_unstemmed Effect of undernutrition on the cranial growth of the rat: An intergenerational study
title_sort Effect of undernutrition on the cranial growth of the rat: An intergenerational study
dc.creator.none.fl_str_mv Cesani Rossi, María Florencia
Orden, Alicia Bibiana
Zucchi, Mariel
Muñe, Maria Cristina
Oyhenart, Evelia Edith
Pucciarelli, Hector Mario
author Cesani Rossi, María Florencia
author_facet Cesani Rossi, María Florencia
Orden, Alicia Bibiana
Zucchi, Mariel
Muñe, Maria Cristina
Oyhenart, Evelia Edith
Pucciarelli, Hector Mario
author_role author
author2 Orden, Alicia Bibiana
Zucchi, Mariel
Muñe, Maria Cristina
Oyhenart, Evelia Edith
Pucciarelli, Hector Mario
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Rat
Skull Growth
Transgenerational Undernutrition
topic Rat
Skull Growth
Transgenerational Undernutrition
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The cumulative effect of undernutrition on successive generations was tested. The cranial growth of three generations of undernourished rats (F1, F2, F3) was compared to that of the parental generation (P), in order to (1) measure the extent to which the growth of each facial and neurocranial functional component was retarded when animals were undernourished and (2) determine whether any cumulative effect between generations can be found. The P generation was fed ad libitum, and the undernourished generations were fed 50% (F1) and 75% (F2 and F3) of the parental diet. Nine radiographs were taken from the age of 20-100 days. The length, width and height of the neurocranial and facial components were measured on each radiograph. Neurocranial (VNI), facial (VFI), and neurofacial (NFI) indices were calculated. Data were processed by the Kruskal-Wallis and Kolmogorov-Smirnov tests. An impairment in neurocranial and facial growth was found, the latter being more affected than the former in F1. At variance, the neurocranium was more affected than the face in F2 and F3, resulting in variations of the shape of the skull. A cumulative effect of moderate transgenerational undernutrition was evident and points to the need for further analysis on this topic. Copyright © 2003 S. Karger AG, Basel.
Fil: Cesani Rossi, María Florencia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
Fil: Orden, Alicia Bibiana. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
Fil: Zucchi, Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Fil: Muñe, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Fil: Oyhenart, Evelia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
Fil: Pucciarelli, Hector Mario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Centro de Investigaciones en Genética Básica y Aplicada; Argentina
description The cumulative effect of undernutrition on successive generations was tested. The cranial growth of three generations of undernourished rats (F1, F2, F3) was compared to that of the parental generation (P), in order to (1) measure the extent to which the growth of each facial and neurocranial functional component was retarded when animals were undernourished and (2) determine whether any cumulative effect between generations can be found. The P generation was fed ad libitum, and the undernourished generations were fed 50% (F1) and 75% (F2 and F3) of the parental diet. Nine radiographs were taken from the age of 20-100 days. The length, width and height of the neurocranial and facial components were measured on each radiograph. Neurocranial (VNI), facial (VFI), and neurofacial (NFI) indices were calculated. Data were processed by the Kruskal-Wallis and Kolmogorov-Smirnov tests. An impairment in neurocranial and facial growth was found, the latter being more affected than the former in F1. At variance, the neurocranium was more affected than the face in F2 and F3, resulting in variations of the shape of the skull. A cumulative effect of moderate transgenerational undernutrition was evident and points to the need for further analysis on this topic. Copyright © 2003 S. Karger AG, Basel.
publishDate 2003
dc.date.none.fl_str_mv 2003-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/83711
Cesani Rossi, María Florencia; Orden, Alicia Bibiana; Zucchi, Mariel; Muñe, Maria Cristina; Oyhenart, Evelia Edith; et al.; Effect of undernutrition on the cranial growth of the rat: An intergenerational study; Karger; Cells Tissues Organs; 174; 3; 12-2003; 129-135
1422-6405
CONICET Digital
CONICET
url http://hdl.handle.net/11336/83711
identifier_str_mv Cesani Rossi, María Florencia; Orden, Alicia Bibiana; Zucchi, Mariel; Muñe, Maria Cristina; Oyhenart, Evelia Edith; et al.; Effect of undernutrition on the cranial growth of the rat: An intergenerational study; Karger; Cells Tissues Organs; 174; 3; 12-2003; 129-135
1422-6405
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1159/000071153
info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/71153
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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