Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)

Autores
Guevara, Manuel Alejandro; Lorenzo Aquaro, Sofía Ana; Giai, Marcos; Gargiulo, Pascual Angel
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The pig (Sus scrofa domestica) is an animal used as an experimental model in surgical procedures. This makes the use of anaesthesia necessary. The present study constitutes a comparison between two different ketamine/xylazine concentration protocols. One protocol used ketamine 10% + xylazine 10% (high concentration), and the other ketamine 5% + xylazine 2% (low concentration). Concentrations were chosen since these are the most common presentations in the veterinary market. In the present experiments, twenty male and female pigs (Sus crofa domestica; 20 kg each), were assigned into two different groups. The first one was integrated by pigs treated with high concentration protocol (n = 10), and the second one, composed by pigs that received low concentration protocol (n = 10). Parameters measured were the time in which the animals were placed in sternal decubitus, and the heart rate. The effects of these drugs were considered not only specifically in its sedative effects, but also in the respiratory system. Based on these results, we conclude that the first protocol showed better results than the second one. The time in which the animals were placed in sternal decubitus was lower in the first one (p < 0.001). Differences between the effects on the respiratory system (p = 0.37) and sedative effects (p = 0.87) were not significant, even when focusing on the last measurement, higher concentration protocol was twenty percent (20%) more effective than lower.
Fil: Guevara, Manuel Alejandro. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Lorenzo Aquaro, Sofía Ana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Giai, Marcos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gargiulo, Pascual Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Fundación Corporación Tecnológica Latinoamericana; Argentina
Materia
Ketamine
Xylazine
Sus scrofa domestica
Pig
Anaesthesia
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/98627
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/98627
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)Guevara, Manuel AlejandroLorenzo Aquaro, Sofía AnaGiai, MarcosGargiulo, Pascual AngelKetamineXylazineSus scrofa domesticaPigAnaesthesiahttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The pig (Sus scrofa domestica) is an animal used as an experimental model in surgical procedures. This makes the use of anaesthesia necessary. The present study constitutes a comparison between two different ketamine/xylazine concentration protocols. One protocol used ketamine 10% + xylazine 10% (high concentration), and the other ketamine 5% + xylazine 2% (low concentration). Concentrations were chosen since these are the most common presentations in the veterinary market. In the present experiments, twenty male and female pigs (Sus crofa domestica; 20 kg each), were assigned into two different groups. The first one was integrated by pigs treated with high concentration protocol (n = 10), and the second one, composed by pigs that received low concentration protocol (n = 10). Parameters measured were the time in which the animals were placed in sternal decubitus, and the heart rate. The effects of these drugs were considered not only specifically in its sedative effects, but also in the respiratory system. Based on these results, we conclude that the first protocol showed better results than the second one. The time in which the animals were placed in sternal decubitus was lower in the first one (p < 0.001). Differences between the effects on the respiratory system (p = 0.37) and sedative effects (p = 0.87) were not significant, even when focusing on the last measurement, higher concentration protocol was twenty percent (20%) more effective than lower.Fil: Guevara, Manuel Alejandro. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Lorenzo Aquaro, Sofía Ana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFil: Giai, Marcos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gargiulo, Pascual Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Fundación Corporación Tecnológica Latinoamericana; ArgentinaRede Brasileira de Informações Biológicas - Rebibio2018-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttp://hdl.handle.net/11336/98627Guevara, Manuel Alejandro; Lorenzo Aquaro, Sofía Ana; Giai, Marcos; Gargiulo, Pascual Angel; Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica); Rede Brasileira de Informações Biológicas - Rebibio; Brazilian Journal of Biological Sciences; 5; 11; 5-2018; 765-7722358-2731CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.21472/bjbs.051114info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:51:52Zoai:ri.conicet.gov.ar:11336/98627instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:51:52.551CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
title Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
spellingShingle Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
Guevara, Manuel Alejandro
Ketamine
Xylazine
Sus scrofa domestica
Pig
Anaesthesia
title_short Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
title_full Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
title_fullStr Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
title_full_unstemmed Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
title_sort Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica)
dc.creator.none.fl_str_mv Guevara, Manuel Alejandro
Lorenzo Aquaro, Sofía Ana
Giai, Marcos
Gargiulo, Pascual Angel
author Guevara, Manuel Alejandro
author_facet Guevara, Manuel Alejandro
Lorenzo Aquaro, Sofía Ana
Giai, Marcos
Gargiulo, Pascual Angel
author_role author
author2 Lorenzo Aquaro, Sofía Ana
Giai, Marcos
Gargiulo, Pascual Angel
author2_role author
author
author
dc.subject.none.fl_str_mv Ketamine
Xylazine
Sus scrofa domestica
Pig
Anaesthesia
topic Ketamine
Xylazine
Sus scrofa domestica
Pig
Anaesthesia
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The pig (Sus scrofa domestica) is an animal used as an experimental model in surgical procedures. This makes the use of anaesthesia necessary. The present study constitutes a comparison between two different ketamine/xylazine concentration protocols. One protocol used ketamine 10% + xylazine 10% (high concentration), and the other ketamine 5% + xylazine 2% (low concentration). Concentrations were chosen since these are the most common presentations in the veterinary market. In the present experiments, twenty male and female pigs (Sus crofa domestica; 20 kg each), were assigned into two different groups. The first one was integrated by pigs treated with high concentration protocol (n = 10), and the second one, composed by pigs that received low concentration protocol (n = 10). Parameters measured were the time in which the animals were placed in sternal decubitus, and the heart rate. The effects of these drugs were considered not only specifically in its sedative effects, but also in the respiratory system. Based on these results, we conclude that the first protocol showed better results than the second one. The time in which the animals were placed in sternal decubitus was lower in the first one (p < 0.001). Differences between the effects on the respiratory system (p = 0.37) and sedative effects (p = 0.87) were not significant, even when focusing on the last measurement, higher concentration protocol was twenty percent (20%) more effective than lower.
Fil: Guevara, Manuel Alejandro. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Lorenzo Aquaro, Sofía Ana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Giai, Marcos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gargiulo, Pascual Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina. Fundación Corporación Tecnológica Latinoamericana; Argentina
description The pig (Sus scrofa domestica) is an animal used as an experimental model in surgical procedures. This makes the use of anaesthesia necessary. The present study constitutes a comparison between two different ketamine/xylazine concentration protocols. One protocol used ketamine 10% + xylazine 10% (high concentration), and the other ketamine 5% + xylazine 2% (low concentration). Concentrations were chosen since these are the most common presentations in the veterinary market. In the present experiments, twenty male and female pigs (Sus crofa domestica; 20 kg each), were assigned into two different groups. The first one was integrated by pigs treated with high concentration protocol (n = 10), and the second one, composed by pigs that received low concentration protocol (n = 10). Parameters measured were the time in which the animals were placed in sternal decubitus, and the heart rate. The effects of these drugs were considered not only specifically in its sedative effects, but also in the respiratory system. Based on these results, we conclude that the first protocol showed better results than the second one. The time in which the animals were placed in sternal decubitus was lower in the first one (p < 0.001). Differences between the effects on the respiratory system (p = 0.37) and sedative effects (p = 0.87) were not significant, even when focusing on the last measurement, higher concentration protocol was twenty percent (20%) more effective than lower.
publishDate 2018
dc.date.none.fl_str_mv 2018-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/98627
Guevara, Manuel Alejandro; Lorenzo Aquaro, Sofía Ana; Giai, Marcos; Gargiulo, Pascual Angel; Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica); Rede Brasileira de Informações Biológicas - Rebibio; Brazilian Journal of Biological Sciences; 5; 11; 5-2018; 765-772
2358-2731
CONICET Digital
CONICET
url http://hdl.handle.net/11336/98627
identifier_str_mv Guevara, Manuel Alejandro; Lorenzo Aquaro, Sofía Ana; Giai, Marcos; Gargiulo, Pascual Angel; Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica); Rede Brasileira de Informações Biológicas - Rebibio; Brazilian Journal of Biological Sciences; 5; 11; 5-2018; 765-772
2358-2731
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.21472/bjbs.051114
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
dc.publisher.none.fl_str_mv Rede Brasileira de Informações Biológicas - Rebibio
publisher.none.fl_str_mv Rede Brasileira de Informações Biológicas - Rebibio
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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