Geriatric Depression and Cognitive Impairment: A Follow up Study
- Autores
- Dillon, Carol; Filipin, Federico; Taragano, Fernando Emilio; Heisecke Peralta, Silvina Lidia; López Camelo, Jorge Santiago; Allegri, Ricardo Francisco
- Año de publicación
- 2016
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Introduction: Depression in older adults has become a major problem for public health. A high percentage of this population is under-diagnosed in primary care. The objectives of this work were firstly, to investigate the causes, risk factors, cognitive profile, functional status and quality of life of patients with geriatric depression, and secondly, to make a follow up of these patients. Materials and methods: Patients who consulted for memory problems associated with depression were recruited during the years 2005-2007. A semi-structured neuropsychiatric interview, an extensive neuropsychological battery, and complementary studies were performed. Results: One hundred and one depressive patients and 25 normal controls were evaluated. There was a significant prevalence and incidence of depression in the geriatric population. Significant differences (p<0.05) were found between depressive patients and controls in dyslipidemia, heart disease, cerebrovascular disease, inadequate family support, family history of depression and inactivity (OR 6.5). A global cognitive impairment was frequently associated with depression. Depression caused an alteration in functional status. Follow up results: From the 101 patients evaluated only 61 attended to the follow up visit (61.4%). All patients were indicated antidepressant treatment. Of these, only 36 patients continue with the treatment indicated in the baseline visit. Of the patients who were in antidepressant treatment (n=36) 46.6% had an excellent to good response, and 13.3% had a response from fair to poor. The main causes of poor response were adverse effects, low-dose and treatment neglect. Of the reevaluated patients, 56.6% improved in cognition or mood. The greatest improvement was observed in depression and anxiety affective symptoms. Within the cognitive profile, memory and attention trend to improve with medical treatment. Conclusion: Depression is a prevalent disease in the elderly population. It is important to implement health policies to inform the community, prevent associated risk factors, and promote appropriate treatments and rehabilitation. This condition not only affects the patient but also their environment.
Fil: Dillon, Carol. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Filipin, Federico. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina
Fil: Taragano, Fernando Emilio. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Heisecke Peralta, Silvina Lidia. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: López Camelo, Jorge Santiago. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Allegri, Ricardo Francisco. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina - Materia
-
DEPRESSION
GERIATRICS
RISK FACTORS
COGNITIVE IMPAIRMENT - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/113921
Ver los metadatos del registro completo
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Geriatric Depression and Cognitive Impairment: A Follow up StudyDillon, CarolFilipin, FedericoTaragano, Fernando EmilioHeisecke Peralta, Silvina LidiaLópez Camelo, Jorge SantiagoAllegri, Ricardo FranciscoDEPRESSIONGERIATRICSRISK FACTORSCOGNITIVE IMPAIRMENThttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Introduction: Depression in older adults has become a major problem for public health. A high percentage of this population is under-diagnosed in primary care. The objectives of this work were firstly, to investigate the causes, risk factors, cognitive profile, functional status and quality of life of patients with geriatric depression, and secondly, to make a follow up of these patients. Materials and methods: Patients who consulted for memory problems associated with depression were recruited during the years 2005-2007. A semi-structured neuropsychiatric interview, an extensive neuropsychological battery, and complementary studies were performed. Results: One hundred and one depressive patients and 25 normal controls were evaluated. There was a significant prevalence and incidence of depression in the geriatric population. Significant differences (p<0.05) were found between depressive patients and controls in dyslipidemia, heart disease, cerebrovascular disease, inadequate family support, family history of depression and inactivity (OR 6.5). A global cognitive impairment was frequently associated with depression. Depression caused an alteration in functional status. Follow up results: From the 101 patients evaluated only 61 attended to the follow up visit (61.4%). All patients were indicated antidepressant treatment. Of these, only 36 patients continue with the treatment indicated in the baseline visit. Of the patients who were in antidepressant treatment (n=36) 46.6% had an excellent to good response, and 13.3% had a response from fair to poor. The main causes of poor response were adverse effects, low-dose and treatment neglect. Of the reevaluated patients, 56.6% improved in cognition or mood. The greatest improvement was observed in depression and anxiety affective symptoms. Within the cognitive profile, memory and attention trend to improve with medical treatment. Conclusion: Depression is a prevalent disease in the elderly population. It is important to implement health policies to inform the community, prevent associated risk factors, and promote appropriate treatments and rehabilitation. This condition not only affects the patient but also their environment.Fil: Dillon, Carol. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Filipin, Federico. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; ArgentinaFil: Taragano, Fernando Emilio. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Heisecke Peralta, Silvina Lidia. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: López Camelo, Jorge Santiago. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Allegri, Ricardo Francisco. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaOmics International2016-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/113921Dillon, Carol; Filipin, Federico; Taragano, Fernando Emilio; Heisecke Peralta, Silvina Lidia; López Camelo, Jorge Santiago; et al.; Geriatric Depression and Cognitive Impairment: A Follow up Study; Omics International; Journal of Gerontology & Geriatric Research; 5; 4; 6-2016; 317-3252167-7182CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.4172/2167-7182.1000317info:eu-repo/semantics/altIdentifier/url/https://www.longdom.org/abstract/geriatric-depression-and-cognitive-impairment-a-follow-up-study-51033.htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:41:24Zoai:ri.conicet.gov.ar:11336/113921instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:41:24.815CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
title |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
spellingShingle |
Geriatric Depression and Cognitive Impairment: A Follow up Study Dillon, Carol DEPRESSION GERIATRICS RISK FACTORS COGNITIVE IMPAIRMENT |
title_short |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
title_full |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
title_fullStr |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
title_full_unstemmed |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
title_sort |
Geriatric Depression and Cognitive Impairment: A Follow up Study |
dc.creator.none.fl_str_mv |
Dillon, Carol Filipin, Federico Taragano, Fernando Emilio Heisecke Peralta, Silvina Lidia López Camelo, Jorge Santiago Allegri, Ricardo Francisco |
author |
Dillon, Carol |
author_facet |
Dillon, Carol Filipin, Federico Taragano, Fernando Emilio Heisecke Peralta, Silvina Lidia López Camelo, Jorge Santiago Allegri, Ricardo Francisco |
author_role |
author |
author2 |
Filipin, Federico Taragano, Fernando Emilio Heisecke Peralta, Silvina Lidia López Camelo, Jorge Santiago Allegri, Ricardo Francisco |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
DEPRESSION GERIATRICS RISK FACTORS COGNITIVE IMPAIRMENT |
topic |
DEPRESSION GERIATRICS RISK FACTORS COGNITIVE IMPAIRMENT |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.2 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Introduction: Depression in older adults has become a major problem for public health. A high percentage of this population is under-diagnosed in primary care. The objectives of this work were firstly, to investigate the causes, risk factors, cognitive profile, functional status and quality of life of patients with geriatric depression, and secondly, to make a follow up of these patients. Materials and methods: Patients who consulted for memory problems associated with depression were recruited during the years 2005-2007. A semi-structured neuropsychiatric interview, an extensive neuropsychological battery, and complementary studies were performed. Results: One hundred and one depressive patients and 25 normal controls were evaluated. There was a significant prevalence and incidence of depression in the geriatric population. Significant differences (p<0.05) were found between depressive patients and controls in dyslipidemia, heart disease, cerebrovascular disease, inadequate family support, family history of depression and inactivity (OR 6.5). A global cognitive impairment was frequently associated with depression. Depression caused an alteration in functional status. Follow up results: From the 101 patients evaluated only 61 attended to the follow up visit (61.4%). All patients were indicated antidepressant treatment. Of these, only 36 patients continue with the treatment indicated in the baseline visit. Of the patients who were in antidepressant treatment (n=36) 46.6% had an excellent to good response, and 13.3% had a response from fair to poor. The main causes of poor response were adverse effects, low-dose and treatment neglect. Of the reevaluated patients, 56.6% improved in cognition or mood. The greatest improvement was observed in depression and anxiety affective symptoms. Within the cognitive profile, memory and attention trend to improve with medical treatment. Conclusion: Depression is a prevalent disease in the elderly population. It is important to implement health policies to inform the community, prevent associated risk factors, and promote appropriate treatments and rehabilitation. This condition not only affects the patient but also their environment. Fil: Dillon, Carol. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Filipin, Federico. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina Fil: Taragano, Fernando Emilio. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Heisecke Peralta, Silvina Lidia. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: López Camelo, Jorge Santiago. Centro de Educaciones Médicas e Investigación Clínica "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Allegri, Ricardo Francisco. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina |
description |
Introduction: Depression in older adults has become a major problem for public health. A high percentage of this population is under-diagnosed in primary care. The objectives of this work were firstly, to investigate the causes, risk factors, cognitive profile, functional status and quality of life of patients with geriatric depression, and secondly, to make a follow up of these patients. Materials and methods: Patients who consulted for memory problems associated with depression were recruited during the years 2005-2007. A semi-structured neuropsychiatric interview, an extensive neuropsychological battery, and complementary studies were performed. Results: One hundred and one depressive patients and 25 normal controls were evaluated. There was a significant prevalence and incidence of depression in the geriatric population. Significant differences (p<0.05) were found between depressive patients and controls in dyslipidemia, heart disease, cerebrovascular disease, inadequate family support, family history of depression and inactivity (OR 6.5). A global cognitive impairment was frequently associated with depression. Depression caused an alteration in functional status. Follow up results: From the 101 patients evaluated only 61 attended to the follow up visit (61.4%). All patients were indicated antidepressant treatment. Of these, only 36 patients continue with the treatment indicated in the baseline visit. Of the patients who were in antidepressant treatment (n=36) 46.6% had an excellent to good response, and 13.3% had a response from fair to poor. The main causes of poor response were adverse effects, low-dose and treatment neglect. Of the reevaluated patients, 56.6% improved in cognition or mood. The greatest improvement was observed in depression and anxiety affective symptoms. Within the cognitive profile, memory and attention trend to improve with medical treatment. Conclusion: Depression is a prevalent disease in the elderly population. It is important to implement health policies to inform the community, prevent associated risk factors, and promote appropriate treatments and rehabilitation. This condition not only affects the patient but also their environment. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/113921 Dillon, Carol; Filipin, Federico; Taragano, Fernando Emilio; Heisecke Peralta, Silvina Lidia; López Camelo, Jorge Santiago; et al.; Geriatric Depression and Cognitive Impairment: A Follow up Study; Omics International; Journal of Gerontology & Geriatric Research; 5; 4; 6-2016; 317-325 2167-7182 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/113921 |
identifier_str_mv |
Dillon, Carol; Filipin, Federico; Taragano, Fernando Emilio; Heisecke Peralta, Silvina Lidia; López Camelo, Jorge Santiago; et al.; Geriatric Depression and Cognitive Impairment: A Follow up Study; Omics International; Journal of Gerontology & Geriatric Research; 5; 4; 6-2016; 317-325 2167-7182 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.4172/2167-7182.1000317 info:eu-repo/semantics/altIdentifier/url/https://www.longdom.org/abstract/geriatric-depression-and-cognitive-impairment-a-follow-up-study-51033.html |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Omics International |
publisher.none.fl_str_mv |
Omics International |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |