Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression

Autores
Tuchscherr, Lorena Paola Nelly; Lffler, Bettina; Buzzola, Fernanda Roxana; Sordelli, Daniel Oscar
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A vast array of virulence factors enable Staphylococcus aureus to readily adapt to different environmental niches in diverse hosts. The cap gene cluster is present in almost all relevant clinical S. aureus isolates and capsular polysaccharide expression is apparent in isolates from patients with acute infection. The number of S. aureus isolates from patients with chronic infections that do not express capsular polysaccharide, however, is significantly high, indicating that loss of capsular polysaccharide expression may be a key S. aureus feature associated with persistence. The role of the loss of capsular polysaccharide expression as well as the emergence of other defined phenotypes and their relevance to persistence of S. aureus and chronicity of the infection is discussed in this article. © 2010 Future Medicine Ltd.
Fil: Tuchscherr, Lorena Paola Nelly. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universitätsklinikum Münste; Alemania
Fil: Lffler, Bettina. Universitätsklinikum Münste; Alemania
Fil: Buzzola, Fernanda Roxana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
Fil: Sordelli, Daniel Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
Materia
Capsule
Chronic
Evolution
Infection
Persistence
Staphylococcus Aureus
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/67627
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expressionTuchscherr, Lorena Paola NellyLffler, BettinaBuzzola, Fernanda RoxanaSordelli, Daniel OscarCapsuleChronicEvolutionInfectionPersistenceStaphylococcus Aureushttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3A vast array of virulence factors enable Staphylococcus aureus to readily adapt to different environmental niches in diverse hosts. The cap gene cluster is present in almost all relevant clinical S. aureus isolates and capsular polysaccharide expression is apparent in isolates from patients with acute infection. The number of S. aureus isolates from patients with chronic infections that do not express capsular polysaccharide, however, is significantly high, indicating that loss of capsular polysaccharide expression may be a key S. aureus feature associated with persistence. The role of the loss of capsular polysaccharide expression as well as the emergence of other defined phenotypes and their relevance to persistence of S. aureus and chronicity of the infection is discussed in this article. © 2010 Future Medicine Ltd.Fil: Tuchscherr, Lorena Paola Nelly. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universitätsklinikum Münste; AlemaniaFil: Lffler, Bettina. Universitätsklinikum Münste; AlemaniaFil: Buzzola, Fernanda Roxana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; ArgentinaFil: Sordelli, Daniel Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; ArgentinaFuture Medicine2010-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/67627Tuchscherr, Lorena Paola Nelly; Lffler, Bettina; Buzzola, Fernanda Roxana; Sordelli, Daniel Oscar; Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression; Future Medicine; Future Microbiology; 5; 12; 12-2010; 1823-18321746-0913CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.2217/fmb.10.147info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/abs/10.2217/fmb.10.147info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:46:44Zoai:ri.conicet.gov.ar:11336/67627instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:46:44.713CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
title Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
spellingShingle Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
Tuchscherr, Lorena Paola Nelly
Capsule
Chronic
Evolution
Infection
Persistence
Staphylococcus Aureus
title_short Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
title_full Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
title_fullStr Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
title_full_unstemmed Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
title_sort Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression
dc.creator.none.fl_str_mv Tuchscherr, Lorena Paola Nelly
Lffler, Bettina
Buzzola, Fernanda Roxana
Sordelli, Daniel Oscar
author Tuchscherr, Lorena Paola Nelly
author_facet Tuchscherr, Lorena Paola Nelly
Lffler, Bettina
Buzzola, Fernanda Roxana
Sordelli, Daniel Oscar
author_role author
author2 Lffler, Bettina
Buzzola, Fernanda Roxana
Sordelli, Daniel Oscar
author2_role author
author
author
dc.subject.none.fl_str_mv Capsule
Chronic
Evolution
Infection
Persistence
Staphylococcus Aureus
topic Capsule
Chronic
Evolution
Infection
Persistence
Staphylococcus Aureus
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv A vast array of virulence factors enable Staphylococcus aureus to readily adapt to different environmental niches in diverse hosts. The cap gene cluster is present in almost all relevant clinical S. aureus isolates and capsular polysaccharide expression is apparent in isolates from patients with acute infection. The number of S. aureus isolates from patients with chronic infections that do not express capsular polysaccharide, however, is significantly high, indicating that loss of capsular polysaccharide expression may be a key S. aureus feature associated with persistence. The role of the loss of capsular polysaccharide expression as well as the emergence of other defined phenotypes and their relevance to persistence of S. aureus and chronicity of the infection is discussed in this article. © 2010 Future Medicine Ltd.
Fil: Tuchscherr, Lorena Paola Nelly. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universitätsklinikum Münste; Alemania
Fil: Lffler, Bettina. Universitätsklinikum Münste; Alemania
Fil: Buzzola, Fernanda Roxana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
Fil: Sordelli, Daniel Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
description A vast array of virulence factors enable Staphylococcus aureus to readily adapt to different environmental niches in diverse hosts. The cap gene cluster is present in almost all relevant clinical S. aureus isolates and capsular polysaccharide expression is apparent in isolates from patients with acute infection. The number of S. aureus isolates from patients with chronic infections that do not express capsular polysaccharide, however, is significantly high, indicating that loss of capsular polysaccharide expression may be a key S. aureus feature associated with persistence. The role of the loss of capsular polysaccharide expression as well as the emergence of other defined phenotypes and their relevance to persistence of S. aureus and chronicity of the infection is discussed in this article. © 2010 Future Medicine Ltd.
publishDate 2010
dc.date.none.fl_str_mv 2010-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/67627
Tuchscherr, Lorena Paola Nelly; Lffler, Bettina; Buzzola, Fernanda Roxana; Sordelli, Daniel Oscar; Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression; Future Medicine; Future Microbiology; 5; 12; 12-2010; 1823-1832
1746-0913
CONICET Digital
CONICET
url http://hdl.handle.net/11336/67627
identifier_str_mv Tuchscherr, Lorena Paola Nelly; Lffler, Bettina; Buzzola, Fernanda Roxana; Sordelli, Daniel Oscar; Staphylococcus aureus adaptation to the host and persistence: Role of loss of capsular polysaccharide expression; Future Medicine; Future Microbiology; 5; 12; 12-2010; 1823-1832
1746-0913
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.2217/fmb.10.147
info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/abs/10.2217/fmb.10.147
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Future Medicine
publisher.none.fl_str_mv Future Medicine
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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