Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina

Autores
Colussi, Carlina Leila; Racigh, Nora; Poletta, Gisela Laura; Simoniello, Maria Fernanda
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Introduction: Congenital anomalies (CAs) are abnormalities in intrauterine development and are one of the main causes of burden disease, especially in low and middle-income countries. Many environmental and maternal risk factors could lead to these pathologies. The aim of this study was to identify different types of CAs, determine their frequency and identify their possible association with maternal sociodemographic and lifestyle risk factors among patients from Santa Fe Province, Argentina. Material and methods: An observational cases and control pilot study was conducted in 2018 and 2019 on 280 postpartum mothers of newborn babies with any CA (cases, n = 64) and without a CA (controls, n = 216) attending public hospitals. A face-to-face questionnaire was completed, and clinical histories were required to obtain information on maternal sociodemographic factors, gynecological events, health state, lifestyle habits and child diagnoses. Results: Polymalphormations and neural tube defects were the most frequent CA observed. Differences between cases and control groups, as well as between places of residence, were given by gestational age, type of delivery and newborn birth weight, all of which are preventable variables. A slight association between maternal diabetes and the occurrence of cases was found. Discussion: Maternal place of origin is a factor of inequity in terms of gynecology variables which describes a deeper background in sanitary reality from Santa Fe Province that would have a large impact on future adults born preterm. The results highlight the necessity of generating both sanitary tools for maternal-child health policies and environmental evaluations, which remains a permanent challenge of the Argentine public health system.
Fil: Colussi, Carlina Leila. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina
Fil: Racigh, Nora. Gobierno de la Provincia de Santa Fe. Hospital de Niños Doctor Orlando Alassia.; Argentina
Fil: Poletta, Gisela Laura. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Simoniello, Maria Fernanda. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina
Materia
BIRTH DEFECTS
PERINATAL MEDICINE
LIFESTYLE
PUBLIC HEALTH
RISK FACTORS
MOTHER-CHILD RELATIONSHIP
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/218893
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/218893
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from ArgentinaColussi, Carlina LeilaRacigh, NoraPoletta, Gisela LauraSimoniello, Maria FernandaBIRTH DEFECTSPERINATAL MEDICINELIFESTYLEPUBLIC HEALTHRISK FACTORSMOTHER-CHILD RELATIONSHIPhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Introduction: Congenital anomalies (CAs) are abnormalities in intrauterine development and are one of the main causes of burden disease, especially in low and middle-income countries. Many environmental and maternal risk factors could lead to these pathologies. The aim of this study was to identify different types of CAs, determine their frequency and identify their possible association with maternal sociodemographic and lifestyle risk factors among patients from Santa Fe Province, Argentina. Material and methods: An observational cases and control pilot study was conducted in 2018 and 2019 on 280 postpartum mothers of newborn babies with any CA (cases, n = 64) and without a CA (controls, n = 216) attending public hospitals. A face-to-face questionnaire was completed, and clinical histories were required to obtain information on maternal sociodemographic factors, gynecological events, health state, lifestyle habits and child diagnoses. Results: Polymalphormations and neural tube defects were the most frequent CA observed. Differences between cases and control groups, as well as between places of residence, were given by gestational age, type of delivery and newborn birth weight, all of which are preventable variables. A slight association between maternal diabetes and the occurrence of cases was found. Discussion: Maternal place of origin is a factor of inequity in terms of gynecology variables which describes a deeper background in sanitary reality from Santa Fe Province that would have a large impact on future adults born preterm. The results highlight the necessity of generating both sanitary tools for maternal-child health policies and environmental evaluations, which remains a permanent challenge of the Argentine public health system.Fil: Colussi, Carlina Leila. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; ArgentinaFil: Racigh, Nora. Gobierno de la Provincia de Santa Fe. Hospital de Niños Doctor Orlando Alassia.; ArgentinaFil: Poletta, Gisela Laura. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Simoniello, Maria Fernanda. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; ArgentinaHygeia Press di Corridori Marinella2023-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/218893Colussi, Carlina Leila; Racigh, Nora; Poletta, Gisela Laura; Simoniello, Maria Fernanda; Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina; Hygeia Press di Corridori Marinella; Journal of Pediatric and Neonatal Individualized Medicine; 12; 1; 1-2023; 1-112281-0692CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://jpnim.com/index.php/jpnim/article/view/e120109info:eu-repo/semantics/altIdentifier/doi/10.7363/120109info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:39:07Zoai:ri.conicet.gov.ar:11336/218893instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:39:07.894CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
title Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
spellingShingle Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
Colussi, Carlina Leila
BIRTH DEFECTS
PERINATAL MEDICINE
LIFESTYLE
PUBLIC HEALTH
RISK FACTORS
MOTHER-CHILD RELATIONSHIP
title_short Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
title_full Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
title_fullStr Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
title_full_unstemmed Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
title_sort Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina
dc.creator.none.fl_str_mv Colussi, Carlina Leila
Racigh, Nora
Poletta, Gisela Laura
Simoniello, Maria Fernanda
author Colussi, Carlina Leila
author_facet Colussi, Carlina Leila
Racigh, Nora
Poletta, Gisela Laura
Simoniello, Maria Fernanda
author_role author
author2 Racigh, Nora
Poletta, Gisela Laura
Simoniello, Maria Fernanda
author2_role author
author
author
dc.subject.none.fl_str_mv BIRTH DEFECTS
PERINATAL MEDICINE
LIFESTYLE
PUBLIC HEALTH
RISK FACTORS
MOTHER-CHILD RELATIONSHIP
topic BIRTH DEFECTS
PERINATAL MEDICINE
LIFESTYLE
PUBLIC HEALTH
RISK FACTORS
MOTHER-CHILD RELATIONSHIP
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Introduction: Congenital anomalies (CAs) are abnormalities in intrauterine development and are one of the main causes of burden disease, especially in low and middle-income countries. Many environmental and maternal risk factors could lead to these pathologies. The aim of this study was to identify different types of CAs, determine their frequency and identify their possible association with maternal sociodemographic and lifestyle risk factors among patients from Santa Fe Province, Argentina. Material and methods: An observational cases and control pilot study was conducted in 2018 and 2019 on 280 postpartum mothers of newborn babies with any CA (cases, n = 64) and without a CA (controls, n = 216) attending public hospitals. A face-to-face questionnaire was completed, and clinical histories were required to obtain information on maternal sociodemographic factors, gynecological events, health state, lifestyle habits and child diagnoses. Results: Polymalphormations and neural tube defects were the most frequent CA observed. Differences between cases and control groups, as well as between places of residence, were given by gestational age, type of delivery and newborn birth weight, all of which are preventable variables. A slight association between maternal diabetes and the occurrence of cases was found. Discussion: Maternal place of origin is a factor of inequity in terms of gynecology variables which describes a deeper background in sanitary reality from Santa Fe Province that would have a large impact on future adults born preterm. The results highlight the necessity of generating both sanitary tools for maternal-child health policies and environmental evaluations, which remains a permanent challenge of the Argentine public health system.
Fil: Colussi, Carlina Leila. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina
Fil: Racigh, Nora. Gobierno de la Provincia de Santa Fe. Hospital de Niños Doctor Orlando Alassia.; Argentina
Fil: Poletta, Gisela Laura. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Simoniello, Maria Fernanda. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Cátedra de Toxicología y Bioquímica Legal; Argentina
description Introduction: Congenital anomalies (CAs) are abnormalities in intrauterine development and are one of the main causes of burden disease, especially in low and middle-income countries. Many environmental and maternal risk factors could lead to these pathologies. The aim of this study was to identify different types of CAs, determine their frequency and identify their possible association with maternal sociodemographic and lifestyle risk factors among patients from Santa Fe Province, Argentina. Material and methods: An observational cases and control pilot study was conducted in 2018 and 2019 on 280 postpartum mothers of newborn babies with any CA (cases, n = 64) and without a CA (controls, n = 216) attending public hospitals. A face-to-face questionnaire was completed, and clinical histories were required to obtain information on maternal sociodemographic factors, gynecological events, health state, lifestyle habits and child diagnoses. Results: Polymalphormations and neural tube defects were the most frequent CA observed. Differences between cases and control groups, as well as between places of residence, were given by gestational age, type of delivery and newborn birth weight, all of which are preventable variables. A slight association between maternal diabetes and the occurrence of cases was found. Discussion: Maternal place of origin is a factor of inequity in terms of gynecology variables which describes a deeper background in sanitary reality from Santa Fe Province that would have a large impact on future adults born preterm. The results highlight the necessity of generating both sanitary tools for maternal-child health policies and environmental evaluations, which remains a permanent challenge of the Argentine public health system.
publishDate 2023
dc.date.none.fl_str_mv 2023-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/218893
Colussi, Carlina Leila; Racigh, Nora; Poletta, Gisela Laura; Simoniello, Maria Fernanda; Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina; Hygeia Press di Corridori Marinella; Journal of Pediatric and Neonatal Individualized Medicine; 12; 1; 1-2023; 1-11
2281-0692
CONICET Digital
CONICET
url http://hdl.handle.net/11336/218893
identifier_str_mv Colussi, Carlina Leila; Racigh, Nora; Poletta, Gisela Laura; Simoniello, Maria Fernanda; Prenatal risk factors for selected congenital anomalies development: A case-control pilot study in postpartum women from Argentina; Hygeia Press di Corridori Marinella; Journal of Pediatric and Neonatal Individualized Medicine; 12; 1; 1-2023; 1-11
2281-0692
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://jpnim.com/index.php/jpnim/article/view/e120109
info:eu-repo/semantics/altIdentifier/doi/10.7363/120109
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hygeia Press di Corridori Marinella
publisher.none.fl_str_mv Hygeia Press di Corridori Marinella
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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