Mucosal immune tolerance at the ocular surface in health and disease

Autores
Galletti, Jeremías Gastón; Guzman, Mauricio; Giordano, Mirta Nilda
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The ocular surface is constantly exposed to environmental irritants, allergens and pathogens, against which it can mount a prompt immune response to preserve its integrity. But to avoid unnecessary inflammation, the ocular surface’s mucosal immune system must also discriminate between harmless and potentially dangerous antigens, a seemingly complicated task. Despite its unique features, the ocular surface is a mucosal lining, and as such, it shares some homeostatic and pathophysiological mechanisms with other mucosal surfaces. The purpose of this review is to explore the mucosal homeostatic immune function of the ocular surface in both the healthy and diseased states, with a special focus on mucosal immunology concepts. The information discussed in this review has been retrieved by PubMed searches for literature published from January 1981 to October 2016.
Fil: Galletti, Jeremías Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Guzman, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Giordano, Mirta Nilda. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Materia
ALLERGIC CONJUNCTIVITIS
CONJUNCTIVAL INFLAMMATION
DRY EYE
MUCOSAL TOLERANCE
OCULAR MUCOSAL IMMUNE SYSTEM
OCULAR SURFACE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/53497
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Mucosal immune tolerance at the ocular surface in health and diseaseGalletti, Jeremías GastónGuzman, MauricioGiordano, Mirta NildaALLERGIC CONJUNCTIVITISCONJUNCTIVAL INFLAMMATIONDRY EYEMUCOSAL TOLERANCEOCULAR MUCOSAL IMMUNE SYSTEMOCULAR SURFACEhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The ocular surface is constantly exposed to environmental irritants, allergens and pathogens, against which it can mount a prompt immune response to preserve its integrity. But to avoid unnecessary inflammation, the ocular surface’s mucosal immune system must also discriminate between harmless and potentially dangerous antigens, a seemingly complicated task. Despite its unique features, the ocular surface is a mucosal lining, and as such, it shares some homeostatic and pathophysiological mechanisms with other mucosal surfaces. The purpose of this review is to explore the mucosal homeostatic immune function of the ocular surface in both the healthy and diseased states, with a special focus on mucosal immunology concepts. The information discussed in this review has been retrieved by PubMed searches for literature published from January 1981 to October 2016.Fil: Galletti, Jeremías Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Guzman, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Giordano, Mirta Nilda. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaWiley Blackwell Publishing, Inc2017-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/53497Galletti, Jeremías Gastón; Guzman, Mauricio; Giordano, Mirta Nilda; Mucosal immune tolerance at the ocular surface in health and disease; Wiley Blackwell Publishing, Inc; Immunology; 150; 4; 4-2017; 397-4070019-28051365-2567CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/imm.12716info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/imm.12716info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:44:18Zoai:ri.conicet.gov.ar:11336/53497instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:44:18.485CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Mucosal immune tolerance at the ocular surface in health and disease
title Mucosal immune tolerance at the ocular surface in health and disease
spellingShingle Mucosal immune tolerance at the ocular surface in health and disease
Galletti, Jeremías Gastón
ALLERGIC CONJUNCTIVITIS
CONJUNCTIVAL INFLAMMATION
DRY EYE
MUCOSAL TOLERANCE
OCULAR MUCOSAL IMMUNE SYSTEM
OCULAR SURFACE
title_short Mucosal immune tolerance at the ocular surface in health and disease
title_full Mucosal immune tolerance at the ocular surface in health and disease
title_fullStr Mucosal immune tolerance at the ocular surface in health and disease
title_full_unstemmed Mucosal immune tolerance at the ocular surface in health and disease
title_sort Mucosal immune tolerance at the ocular surface in health and disease
dc.creator.none.fl_str_mv Galletti, Jeremías Gastón
Guzman, Mauricio
Giordano, Mirta Nilda
author Galletti, Jeremías Gastón
author_facet Galletti, Jeremías Gastón
Guzman, Mauricio
Giordano, Mirta Nilda
author_role author
author2 Guzman, Mauricio
Giordano, Mirta Nilda
author2_role author
author
dc.subject.none.fl_str_mv ALLERGIC CONJUNCTIVITIS
CONJUNCTIVAL INFLAMMATION
DRY EYE
MUCOSAL TOLERANCE
OCULAR MUCOSAL IMMUNE SYSTEM
OCULAR SURFACE
topic ALLERGIC CONJUNCTIVITIS
CONJUNCTIVAL INFLAMMATION
DRY EYE
MUCOSAL TOLERANCE
OCULAR MUCOSAL IMMUNE SYSTEM
OCULAR SURFACE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The ocular surface is constantly exposed to environmental irritants, allergens and pathogens, against which it can mount a prompt immune response to preserve its integrity. But to avoid unnecessary inflammation, the ocular surface’s mucosal immune system must also discriminate between harmless and potentially dangerous antigens, a seemingly complicated task. Despite its unique features, the ocular surface is a mucosal lining, and as such, it shares some homeostatic and pathophysiological mechanisms with other mucosal surfaces. The purpose of this review is to explore the mucosal homeostatic immune function of the ocular surface in both the healthy and diseased states, with a special focus on mucosal immunology concepts. The information discussed in this review has been retrieved by PubMed searches for literature published from January 1981 to October 2016.
Fil: Galletti, Jeremías Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Guzman, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Giordano, Mirta Nilda. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
description The ocular surface is constantly exposed to environmental irritants, allergens and pathogens, against which it can mount a prompt immune response to preserve its integrity. But to avoid unnecessary inflammation, the ocular surface’s mucosal immune system must also discriminate between harmless and potentially dangerous antigens, a seemingly complicated task. Despite its unique features, the ocular surface is a mucosal lining, and as such, it shares some homeostatic and pathophysiological mechanisms with other mucosal surfaces. The purpose of this review is to explore the mucosal homeostatic immune function of the ocular surface in both the healthy and diseased states, with a special focus on mucosal immunology concepts. The information discussed in this review has been retrieved by PubMed searches for literature published from January 1981 to October 2016.
publishDate 2017
dc.date.none.fl_str_mv 2017-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/53497
Galletti, Jeremías Gastón; Guzman, Mauricio; Giordano, Mirta Nilda; Mucosal immune tolerance at the ocular surface in health and disease; Wiley Blackwell Publishing, Inc; Immunology; 150; 4; 4-2017; 397-407
0019-2805
1365-2567
CONICET Digital
CONICET
url http://hdl.handle.net/11336/53497
identifier_str_mv Galletti, Jeremías Gastón; Guzman, Mauricio; Giordano, Mirta Nilda; Mucosal immune tolerance at the ocular surface in health and disease; Wiley Blackwell Publishing, Inc; Immunology; 150; 4; 4-2017; 397-407
0019-2805
1365-2567
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/imm.12716
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/imm.12716
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082953037217792
score 13.22299

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