Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides

Autores
Colinas, Pedro Alfonso
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Native glycosidic bonds in carbohydrates, are sensitive to the presence of enzymes. Thus, design of small molecule mimics (glycomimetics) is an active area of research.This review will focus on the development of a new class of glycomimetics: anomeric and N-glycosyl sulfonamides. These novel compounds have been demonstrated to be enzyme inhibitors or antiproliferative agents.
Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Materia
ANOMERIC SULFONAMIDES
CARBOHYDRATES
ENZYME INHIBITION
GLYCOMIMETICS
N-GLYCOSYL SULFONAMIDES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/197130

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network_name_str CONICET Digital (CONICET)
spelling Novel Glycomimetics: Anomeric and N-Glycosyl SulfonamidesColinas, Pedro AlfonsoANOMERIC SULFONAMIDESCARBOHYDRATESENZYME INHIBITIONGLYCOMIMETICSN-GLYCOSYL SULFONAMIDEShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Native glycosidic bonds in carbohydrates, are sensitive to the presence of enzymes. Thus, design of small molecule mimics (glycomimetics) is an active area of research.This review will focus on the development of a new class of glycomimetics: anomeric and N-glycosyl sulfonamides. These novel compounds have been demonstrated to be enzyme inhibitors or antiproliferative agents.Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaBentham Science Publishers2012-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/197130Colinas, Pedro Alfonso; Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides; Bentham Science Publishers; Current Organic Chemistry; 16; 14; 8-2012; 1670-16761385-2728CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/article/43568info:eu-repo/semantics/altIdentifier/doi/10.2174/138527212800840892info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T11:25:52Zoai:ri.conicet.gov.ar:11336/197130instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 11:25:52.912CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
title Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
spellingShingle Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
Colinas, Pedro Alfonso
ANOMERIC SULFONAMIDES
CARBOHYDRATES
ENZYME INHIBITION
GLYCOMIMETICS
N-GLYCOSYL SULFONAMIDES
title_short Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
title_full Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
title_fullStr Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
title_full_unstemmed Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
title_sort Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides
dc.creator.none.fl_str_mv Colinas, Pedro Alfonso
author Colinas, Pedro Alfonso
author_facet Colinas, Pedro Alfonso
author_role author
dc.subject.none.fl_str_mv ANOMERIC SULFONAMIDES
CARBOHYDRATES
ENZYME INHIBITION
GLYCOMIMETICS
N-GLYCOSYL SULFONAMIDES
topic ANOMERIC SULFONAMIDES
CARBOHYDRATES
ENZYME INHIBITION
GLYCOMIMETICS
N-GLYCOSYL SULFONAMIDES
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Native glycosidic bonds in carbohydrates, are sensitive to the presence of enzymes. Thus, design of small molecule mimics (glycomimetics) is an active area of research.This review will focus on the development of a new class of glycomimetics: anomeric and N-glycosyl sulfonamides. These novel compounds have been demonstrated to be enzyme inhibitors or antiproliferative agents.
Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
description Native glycosidic bonds in carbohydrates, are sensitive to the presence of enzymes. Thus, design of small molecule mimics (glycomimetics) is an active area of research.This review will focus on the development of a new class of glycomimetics: anomeric and N-glycosyl sulfonamides. These novel compounds have been demonstrated to be enzyme inhibitors or antiproliferative agents.
publishDate 2012
dc.date.none.fl_str_mv 2012-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/197130
Colinas, Pedro Alfonso; Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides; Bentham Science Publishers; Current Organic Chemistry; 16; 14; 8-2012; 1670-1676
1385-2728
CONICET Digital
CONICET
url http://hdl.handle.net/11336/197130
identifier_str_mv Colinas, Pedro Alfonso; Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides; Bentham Science Publishers; Current Organic Chemistry; 16; 14; 8-2012; 1670-1676
1385-2728
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/article/43568
info:eu-repo/semantics/altIdentifier/doi/10.2174/138527212800840892
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.001348