Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor

Autores
Mammarella, Enrique José; Rubiolo, Amelia Catalina
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A general mathematical model was developed for predicting the performance and simulation of a packed-bed immobilized enzyme reactor performing a reaction that follows Michaelis–Menten kinetics with competitive product inhibition. The performance of a packed-bed immobilized enzyme reactor was analyzed taking into account the effect of bed swelling on various diffusional phenomena such as axial dispersion, internal and external mass transfer limitations. The numerical solutions were compared with experimental data obtained for a packed-bed reactor operating with β-galactosidase entrapped in Ca-alginate-K-κ-carrageenan gels for lactose hydrolysis.
Fil: Mammarella, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Rubiolo, Amelia Catalina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Materia
Packed-Bed Immobilized Enzyme Reactor
Bed Swelling
Mathematical Model
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/24433
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/24433
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactorMammarella, Enrique JoséRubiolo, Amelia CatalinaPacked-Bed Immobilized Enzyme ReactorBed SwellingMathematical Modelhttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2A general mathematical model was developed for predicting the performance and simulation of a packed-bed immobilized enzyme reactor performing a reaction that follows Michaelis–Menten kinetics with competitive product inhibition. The performance of a packed-bed immobilized enzyme reactor was analyzed taking into account the effect of bed swelling on various diffusional phenomena such as axial dispersion, internal and external mass transfer limitations. The numerical solutions were compared with experimental data obtained for a packed-bed reactor operating with β-galactosidase entrapped in Ca-alginate-K-κ-carrageenan gels for lactose hydrolysis.Fil: Mammarella, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Rubiolo, Amelia Catalina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaElsevier2008-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24433Mammarella, Enrique José; Rubiolo, Amelia Catalina; Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor; Elsevier; Process Biochemistry; 44; 2; 10-2008; 183-1900032-9592CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.procbio.2008.10.009info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S135951130800322Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:09:53Zoai:ri.conicet.gov.ar:11336/24433instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:09:54.252CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
title Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
spellingShingle Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
Mammarella, Enrique José
Packed-Bed Immobilized Enzyme Reactor
Bed Swelling
Mathematical Model
title_short Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
title_full Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
title_fullStr Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
title_full_unstemmed Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
title_sort Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor
dc.creator.none.fl_str_mv Mammarella, Enrique José
Rubiolo, Amelia Catalina
author Mammarella, Enrique José
author_facet Mammarella, Enrique José
Rubiolo, Amelia Catalina
author_role author
author2 Rubiolo, Amelia Catalina
author2_role author
dc.subject.none.fl_str_mv Packed-Bed Immobilized Enzyme Reactor
Bed Swelling
Mathematical Model
topic Packed-Bed Immobilized Enzyme Reactor
Bed Swelling
Mathematical Model
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv A general mathematical model was developed for predicting the performance and simulation of a packed-bed immobilized enzyme reactor performing a reaction that follows Michaelis–Menten kinetics with competitive product inhibition. The performance of a packed-bed immobilized enzyme reactor was analyzed taking into account the effect of bed swelling on various diffusional phenomena such as axial dispersion, internal and external mass transfer limitations. The numerical solutions were compared with experimental data obtained for a packed-bed reactor operating with β-galactosidase entrapped in Ca-alginate-K-κ-carrageenan gels for lactose hydrolysis.
Fil: Mammarella, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Rubiolo, Amelia Catalina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
description A general mathematical model was developed for predicting the performance and simulation of a packed-bed immobilized enzyme reactor performing a reaction that follows Michaelis–Menten kinetics with competitive product inhibition. The performance of a packed-bed immobilized enzyme reactor was analyzed taking into account the effect of bed swelling on various diffusional phenomena such as axial dispersion, internal and external mass transfer limitations. The numerical solutions were compared with experimental data obtained for a packed-bed reactor operating with β-galactosidase entrapped in Ca-alginate-K-κ-carrageenan gels for lactose hydrolysis.
publishDate 2008
dc.date.none.fl_str_mv 2008-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/24433
Mammarella, Enrique José; Rubiolo, Amelia Catalina; Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor; Elsevier; Process Biochemistry; 44; 2; 10-2008; 183-190
0032-9592
CONICET Digital
CONICET
url http://hdl.handle.net/11336/24433
identifier_str_mv Mammarella, Enrique José; Rubiolo, Amelia Catalina; Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor; Elsevier; Process Biochemistry; 44; 2; 10-2008; 183-190
0032-9592
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.procbio.2008.10.009
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S135951130800322X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842270098531811328
score 13.13397

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