Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli

Autores
Perez Mitta, Gonzalo; Albesa, Alberto Gustavo; Trautmann, Christina; Toimil Molares, María Eugenia; Azzaroni, Omar
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The ability of living systems to respond to stimuli and process information has encouraged scientists to develop integrated nanosystems displaying similar functions and capabilities. In this regard, biological pores have been a source of inspiration due to their exquisite control over the transport of ions within cells, a feature that ultimately plays a major role in multiple physiological processes, e.g. transduction of physical stimuli into nervous signals. Developing abiotic nanopores, which respond to certain chemical, biological or physical inputs producing “iontronic” signals, is now a reality thanks to the combination of “soft” surface science with nanofabrication techniques. The interplay between the functional richness of predesigned molecular components and the remarkable physical characteristics of nanopores plays a critical role in the rational integration of molecular functions into nanopore environments, permitting us to envisage nanopore-based biomimetic integrated nanosystems that respond to a variety of external stimuli such as pH, redox potential, molecule concentration, temperature, or light. Transduction of these stimuli into a predefined “iontronic” response can be amplified by exploiting nanoconfinement and physico-chemical effects such as charge distribution, steric constraints, equilibria displacement, or local changes in ionic concentration, to name but a few examples. While in past decades the focus has been mostly on their fundamental aspects and the in-depth study of their interesting transport properties, for several years now nanopore research has started to shift towards specific practical applications. This work is dedicated to bringing together the latest developments in the use of nanopores as “iontronic” transducing elements. Our aim is to show the wide potential of abiotic nanopores in sensing and signal transduction and also to promote the potential of this technology among doctoral students, postdocs, and researchers. We believe that even a casual reader of this perspective will not fail to be impressed by the wealth of opportunities that solid-state nanopores can offer to the transduction of biological, physical and chemical stimuli.
Fil: Perez Mitta, Gonzalo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Albesa, Alberto Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Trautmann, Christina. GSI Helmholtzzentrum für Schwerionenforschung; Alemania. Universitat Technische Darmstadt; Alemania
Fil: Toimil Molares, María Eugenia. GSI Helmholtzzentrum für Schwerionenforschung; Alemania
Fil: Azzaroni, Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Materia
Solid-state nanopores
Iontronics
Ionic rectifiers
Nanoscience
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/63803
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/63803
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuliPerez Mitta, GonzaloAlbesa, Alberto GustavoTrautmann, ChristinaToimil Molares, María EugeniaAzzaroni, OmarSolid-state nanoporesIontronicsIonic rectifiersNanosciencehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The ability of living systems to respond to stimuli and process information has encouraged scientists to develop integrated nanosystems displaying similar functions and capabilities. In this regard, biological pores have been a source of inspiration due to their exquisite control over the transport of ions within cells, a feature that ultimately plays a major role in multiple physiological processes, e.g. transduction of physical stimuli into nervous signals. Developing abiotic nanopores, which respond to certain chemical, biological or physical inputs producing “iontronic” signals, is now a reality thanks to the combination of “soft” surface science with nanofabrication techniques. The interplay between the functional richness of predesigned molecular components and the remarkable physical characteristics of nanopores plays a critical role in the rational integration of molecular functions into nanopore environments, permitting us to envisage nanopore-based biomimetic integrated nanosystems that respond to a variety of external stimuli such as pH, redox potential, molecule concentration, temperature, or light. Transduction of these stimuli into a predefined “iontronic” response can be amplified by exploiting nanoconfinement and physico-chemical effects such as charge distribution, steric constraints, equilibria displacement, or local changes in ionic concentration, to name but a few examples. While in past decades the focus has been mostly on their fundamental aspects and the in-depth study of their interesting transport properties, for several years now nanopore research has started to shift towards specific practical applications. This work is dedicated to bringing together the latest developments in the use of nanopores as “iontronic” transducing elements. Our aim is to show the wide potential of abiotic nanopores in sensing and signal transduction and also to promote the potential of this technology among doctoral students, postdocs, and researchers. We believe that even a casual reader of this perspective will not fail to be impressed by the wealth of opportunities that solid-state nanopores can offer to the transduction of biological, physical and chemical stimuli.Fil: Perez Mitta, Gonzalo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; ArgentinaFil: Albesa, Alberto Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; ArgentinaFil: Trautmann, Christina. GSI Helmholtzzentrum für Schwerionenforschung; Alemania. Universitat Technische Darmstadt; AlemaniaFil: Toimil Molares, María Eugenia. GSI Helmholtzzentrum für Schwerionenforschung; AlemaniaFil: Azzaroni, Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; ArgentinaRoyal Society of Chemistry2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/63803Perez Mitta, Gonzalo; Albesa, Alberto Gustavo; Trautmann, Christina; Toimil Molares, María Eugenia; Azzaroni, Omar; Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli; Royal Society of Chemistry; Chemical Science; 8; 2; 3-2017; 890-9132041-6539CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1039/c6sc04255dinfo:eu-repo/semantics/altIdentifier/url/https://pubs.rsc.org/en/Content/ArticleLanding/2017/SC/C6SC04255Dinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:07:28Zoai:ri.conicet.gov.ar:11336/63803instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:07:28.374CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
title Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
spellingShingle Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
Perez Mitta, Gonzalo
Solid-state nanopores
Iontronics
Ionic rectifiers
Nanoscience
title_short Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
title_full Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
title_fullStr Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
title_full_unstemmed Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
title_sort Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli
dc.creator.none.fl_str_mv Perez Mitta, Gonzalo
Albesa, Alberto Gustavo
Trautmann, Christina
Toimil Molares, María Eugenia
Azzaroni, Omar
author Perez Mitta, Gonzalo
author_facet Perez Mitta, Gonzalo
Albesa, Alberto Gustavo
Trautmann, Christina
Toimil Molares, María Eugenia
Azzaroni, Omar
author_role author
author2 Albesa, Alberto Gustavo
Trautmann, Christina
Toimil Molares, María Eugenia
Azzaroni, Omar
author2_role author
author
author
author
dc.subject.none.fl_str_mv Solid-state nanopores
Iontronics
Ionic rectifiers
Nanoscience
topic Solid-state nanopores
Iontronics
Ionic rectifiers
Nanoscience
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The ability of living systems to respond to stimuli and process information has encouraged scientists to develop integrated nanosystems displaying similar functions and capabilities. In this regard, biological pores have been a source of inspiration due to their exquisite control over the transport of ions within cells, a feature that ultimately plays a major role in multiple physiological processes, e.g. transduction of physical stimuli into nervous signals. Developing abiotic nanopores, which respond to certain chemical, biological or physical inputs producing “iontronic” signals, is now a reality thanks to the combination of “soft” surface science with nanofabrication techniques. The interplay between the functional richness of predesigned molecular components and the remarkable physical characteristics of nanopores plays a critical role in the rational integration of molecular functions into nanopore environments, permitting us to envisage nanopore-based biomimetic integrated nanosystems that respond to a variety of external stimuli such as pH, redox potential, molecule concentration, temperature, or light. Transduction of these stimuli into a predefined “iontronic” response can be amplified by exploiting nanoconfinement and physico-chemical effects such as charge distribution, steric constraints, equilibria displacement, or local changes in ionic concentration, to name but a few examples. While in past decades the focus has been mostly on their fundamental aspects and the in-depth study of their interesting transport properties, for several years now nanopore research has started to shift towards specific practical applications. This work is dedicated to bringing together the latest developments in the use of nanopores as “iontronic” transducing elements. Our aim is to show the wide potential of abiotic nanopores in sensing and signal transduction and also to promote the potential of this technology among doctoral students, postdocs, and researchers. We believe that even a casual reader of this perspective will not fail to be impressed by the wealth of opportunities that solid-state nanopores can offer to the transduction of biological, physical and chemical stimuli.
Fil: Perez Mitta, Gonzalo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Albesa, Alberto Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Trautmann, Christina. GSI Helmholtzzentrum für Schwerionenforschung; Alemania. Universitat Technische Darmstadt; Alemania
Fil: Toimil Molares, María Eugenia. GSI Helmholtzzentrum für Schwerionenforschung; Alemania
Fil: Azzaroni, Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
description The ability of living systems to respond to stimuli and process information has encouraged scientists to develop integrated nanosystems displaying similar functions and capabilities. In this regard, biological pores have been a source of inspiration due to their exquisite control over the transport of ions within cells, a feature that ultimately plays a major role in multiple physiological processes, e.g. transduction of physical stimuli into nervous signals. Developing abiotic nanopores, which respond to certain chemical, biological or physical inputs producing “iontronic” signals, is now a reality thanks to the combination of “soft” surface science with nanofabrication techniques. The interplay between the functional richness of predesigned molecular components and the remarkable physical characteristics of nanopores plays a critical role in the rational integration of molecular functions into nanopore environments, permitting us to envisage nanopore-based biomimetic integrated nanosystems that respond to a variety of external stimuli such as pH, redox potential, molecule concentration, temperature, or light. Transduction of these stimuli into a predefined “iontronic” response can be amplified by exploiting nanoconfinement and physico-chemical effects such as charge distribution, steric constraints, equilibria displacement, or local changes in ionic concentration, to name but a few examples. While in past decades the focus has been mostly on their fundamental aspects and the in-depth study of their interesting transport properties, for several years now nanopore research has started to shift towards specific practical applications. This work is dedicated to bringing together the latest developments in the use of nanopores as “iontronic” transducing elements. Our aim is to show the wide potential of abiotic nanopores in sensing and signal transduction and also to promote the potential of this technology among doctoral students, postdocs, and researchers. We believe that even a casual reader of this perspective will not fail to be impressed by the wealth of opportunities that solid-state nanopores can offer to the transduction of biological, physical and chemical stimuli.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/63803
Perez Mitta, Gonzalo; Albesa, Alberto Gustavo; Trautmann, Christina; Toimil Molares, María Eugenia; Azzaroni, Omar; Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli; Royal Society of Chemistry; Chemical Science; 8; 2; 3-2017; 890-913
2041-6539
CONICET Digital
CONICET
url http://hdl.handle.net/11336/63803
identifier_str_mv Perez Mitta, Gonzalo; Albesa, Alberto Gustavo; Trautmann, Christina; Toimil Molares, María Eugenia; Azzaroni, Omar; Bioinspired integrated nanosystems based on solid-state nanopores: “iontronic” transduction of biological, chemical and physical stimuli; Royal Society of Chemistry; Chemical Science; 8; 2; 3-2017; 890-913
2041-6539
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1039/c6sc04255d
info:eu-repo/semantics/altIdentifier/url/https://pubs.rsc.org/en/Content/ArticleLanding/2017/SC/C6SC04255D
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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