"Time sweet time": circadian characterization of galectin-1 null mice

Autores
Casiraghi, Leandro Pablo; Croci Russo, Diego Omar; Poirier, Francoise; Rabinovich, Gabriel Adrián; Golombek, Diego Andres
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Recent evidence suggests a two-way interaction between the immune and circadian systems. Circadian control of immune factors, as well as the effect of immunological variables on circadian rhythms, might be key elements in both physiological and pathological responses to the environment. Among these relevant factors, galectin-1 is a member of a family of evolutionarily-conserved glycan-binding proteins with both extracellular and intracellular effects, playing important roles in immune cell processes and inflammatory responses. Many of these actions have been studied through the use of mice with a null mutation in the galectin-1 (Lgals1) gene. To further analyze the role of endogenous galectin-1 in vivo, we aimed to characterize the circadian behavior of galectin-1 null (Lgals1-/-) mice.
Fil: Casiraghi, Leandro Pablo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Croci Russo, Diego Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Poirier, Francoise. Universite Paris Diderot - Paris 7; Francia
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Golombek, Diego Andres. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Galectin
Wheel Running
Mutant
Biological Rhythms
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/14254
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling "Time sweet time": circadian characterization of galectin-1 null miceCasiraghi, Leandro PabloCroci Russo, Diego OmarPoirier, FrancoiseRabinovich, Gabriel AdriánGolombek, Diego AndresGalectinWheel RunningMutantBiological Rhythmshttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Recent evidence suggests a two-way interaction between the immune and circadian systems. Circadian control of immune factors, as well as the effect of immunological variables on circadian rhythms, might be key elements in both physiological and pathological responses to the environment. Among these relevant factors, galectin-1 is a member of a family of evolutionarily-conserved glycan-binding proteins with both extracellular and intracellular effects, playing important roles in immune cell processes and inflammatory responses. Many of these actions have been studied through the use of mice with a null mutation in the galectin-1 (Lgals1) gene. To further analyze the role of endogenous galectin-1 in vivo, we aimed to characterize the circadian behavior of galectin-1 null (Lgals1-/-) mice.Fil: Casiraghi, Leandro Pablo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Croci Russo, Diego Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; ArgentinaFil: Poirier, Francoise. Universite Paris Diderot - Paris 7; FranciaFil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; ArgentinaFil: Golombek, Diego Andres. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaBioMed Central2010-04-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14254Casiraghi, Leandro Pablo; Croci Russo, Diego Omar; Poirier, Francoise; Rabinovich, Gabriel Adrián; Golombek, Diego Andres; "Time sweet time": circadian characterization of galectin-1 null mice; BioMed Central; Journal of Circadian Rhythms; 8; 4; 19-4-2010; 1-71740-33911740-3391enginfo:eu-repo/semantics/altIdentifier/doi/10.1186/1740-3391-8-4info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876058/info:eu-repo/semantics/altIdentifier/url/http://europepmc.org/abstract/MED/20403179info:eu-repo/semantics/altIdentifier/url/http://www.jcircadianrhythms.com/articles/10.1186/1740-3391-8-4/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:07:14Zoai:ri.conicet.gov.ar:11336/14254instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:07:14.686CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv "Time sweet time": circadian characterization of galectin-1 null mice
title "Time sweet time": circadian characterization of galectin-1 null mice
spellingShingle "Time sweet time": circadian characterization of galectin-1 null mice
Casiraghi, Leandro Pablo
Galectin
Wheel Running
Mutant
Biological Rhythms
title_short "Time sweet time": circadian characterization of galectin-1 null mice
title_full "Time sweet time": circadian characterization of galectin-1 null mice
title_fullStr "Time sweet time": circadian characterization of galectin-1 null mice
title_full_unstemmed "Time sweet time": circadian characterization of galectin-1 null mice
title_sort "Time sweet time": circadian characterization of galectin-1 null mice
dc.creator.none.fl_str_mv Casiraghi, Leandro Pablo
Croci Russo, Diego Omar
Poirier, Francoise
Rabinovich, Gabriel Adrián
Golombek, Diego Andres
author Casiraghi, Leandro Pablo
author_facet Casiraghi, Leandro Pablo
Croci Russo, Diego Omar
Poirier, Francoise
Rabinovich, Gabriel Adrián
Golombek, Diego Andres
author_role author
author2 Croci Russo, Diego Omar
Poirier, Francoise
Rabinovich, Gabriel Adrián
Golombek, Diego Andres
author2_role author
author
author
author
dc.subject.none.fl_str_mv Galectin
Wheel Running
Mutant
Biological Rhythms
topic Galectin
Wheel Running
Mutant
Biological Rhythms
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Recent evidence suggests a two-way interaction between the immune and circadian systems. Circadian control of immune factors, as well as the effect of immunological variables on circadian rhythms, might be key elements in both physiological and pathological responses to the environment. Among these relevant factors, galectin-1 is a member of a family of evolutionarily-conserved glycan-binding proteins with both extracellular and intracellular effects, playing important roles in immune cell processes and inflammatory responses. Many of these actions have been studied through the use of mice with a null mutation in the galectin-1 (Lgals1) gene. To further analyze the role of endogenous galectin-1 in vivo, we aimed to characterize the circadian behavior of galectin-1 null (Lgals1-/-) mice.
Fil: Casiraghi, Leandro Pablo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Croci Russo, Diego Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Poirier, Francoise. Universite Paris Diderot - Paris 7; Francia
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Golombek, Diego Andres. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Recent evidence suggests a two-way interaction between the immune and circadian systems. Circadian control of immune factors, as well as the effect of immunological variables on circadian rhythms, might be key elements in both physiological and pathological responses to the environment. Among these relevant factors, galectin-1 is a member of a family of evolutionarily-conserved glycan-binding proteins with both extracellular and intracellular effects, playing important roles in immune cell processes and inflammatory responses. Many of these actions have been studied through the use of mice with a null mutation in the galectin-1 (Lgals1) gene. To further analyze the role of endogenous galectin-1 in vivo, we aimed to characterize the circadian behavior of galectin-1 null (Lgals1-/-) mice.
publishDate 2010
dc.date.none.fl_str_mv 2010-04-19
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/14254
Casiraghi, Leandro Pablo; Croci Russo, Diego Omar; Poirier, Francoise; Rabinovich, Gabriel Adrián; Golombek, Diego Andres; "Time sweet time": circadian characterization of galectin-1 null mice; BioMed Central; Journal of Circadian Rhythms; 8; 4; 19-4-2010; 1-7
1740-3391
1740-3391
url http://hdl.handle.net/11336/14254
identifier_str_mv Casiraghi, Leandro Pablo; Croci Russo, Diego Omar; Poirier, Francoise; Rabinovich, Gabriel Adrián; Golombek, Diego Andres; "Time sweet time": circadian characterization of galectin-1 null mice; BioMed Central; Journal of Circadian Rhythms; 8; 4; 19-4-2010; 1-7
1740-3391
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1186/1740-3391-8-4
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876058/
info:eu-repo/semantics/altIdentifier/url/http://europepmc.org/abstract/MED/20403179
info:eu-repo/semantics/altIdentifier/url/http://www.jcircadianrhythms.com/articles/10.1186/1740-3391-8-4/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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