Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine

Autores
Davicino, Roberto Carlos; Alonso, Maria del Rosario; Anesini, Claudia Alejandra
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Coffee (Coffea arabica L.) presents antioxidant effects. Due to negative effects of caffeine (Ca), more people consume decaffeinated coffee. Reactive oxygen species are involved in immune cell physiology controlling proliferation, death and cellular metabolism. The aim of this study was to evaluate the influence of Ca in the effect of normal and decaffeinated coffee on normal mice lymphocytes and macrophages. It were assayed MTT, nitroblue tetrazolium reduction, proliferation assays and superoxide and catalase‐like activities were determined. The decaffeinated coffee induced a decrease in lymphocytes proliferation in all concentrations assayed; this effect was related to an increase of superoxide anion and with the absence of Ca, which by itself increased lymphocytes proliferation through a decrease in H2O2 level by CAT activity “per se.” On macrophages, both extracts induced cell activation not related to the presence of Ca. In conclusion, caffeinated coffee could be better than decaffeinated coffee in the maintenance of the oxidative balance in lymphocytes cells.
Fil: Davicino, Roberto Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Materia
COFFE
LYMPHOCYTES
MACROPHAGES
ANTIOXIDANT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/115256
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeineDavicino, Roberto CarlosAlonso, Maria del RosarioAnesini, Claudia AlejandraCOFFELYMPHOCYTESMACROPHAGESANTIOXIDANThttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Coffee (Coffea arabica L.) presents antioxidant effects. Due to negative effects of caffeine (Ca), more people consume decaffeinated coffee. Reactive oxygen species are involved in immune cell physiology controlling proliferation, death and cellular metabolism. The aim of this study was to evaluate the influence of Ca in the effect of normal and decaffeinated coffee on normal mice lymphocytes and macrophages. It were assayed MTT, nitroblue tetrazolium reduction, proliferation assays and superoxide and catalase‐like activities were determined. The decaffeinated coffee induced a decrease in lymphocytes proliferation in all concentrations assayed; this effect was related to an increase of superoxide anion and with the absence of Ca, which by itself increased lymphocytes proliferation through a decrease in H2O2 level by CAT activity “per se.” On macrophages, both extracts induced cell activation not related to the presence of Ca. In conclusion, caffeinated coffee could be better than decaffeinated coffee in the maintenance of the oxidative balance in lymphocytes cells.Fil: Davicino, Roberto Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaFil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaFil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaWiley Blackwell Publishing, Inc2009-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/115256Davicino, Roberto Carlos; Alonso, Maria del Rosario; Anesini, Claudia Alejandra; Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine; Wiley Blackwell Publishing, Inc; Journal Of Food Biochemistry; 35; 12-2009; 877-8970145-8884CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.onlinelibrary.wiley.com/doi/10.1111/j.1745-4514.2010.00427.x/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1745-4514.2010.00427.x/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:24:19Zoai:ri.conicet.gov.ar:11336/115256instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:24:19.882CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
title Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
spellingShingle Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
Davicino, Roberto Carlos
COFFE
LYMPHOCYTES
MACROPHAGES
ANTIOXIDANT
title_short Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
title_full Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
title_fullStr Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
title_full_unstemmed Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
title_sort Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine
dc.creator.none.fl_str_mv Davicino, Roberto Carlos
Alonso, Maria del Rosario
Anesini, Claudia Alejandra
author Davicino, Roberto Carlos
author_facet Davicino, Roberto Carlos
Alonso, Maria del Rosario
Anesini, Claudia Alejandra
author_role author
author2 Alonso, Maria del Rosario
Anesini, Claudia Alejandra
author2_role author
author
dc.subject.none.fl_str_mv COFFE
LYMPHOCYTES
MACROPHAGES
ANTIOXIDANT
topic COFFE
LYMPHOCYTES
MACROPHAGES
ANTIOXIDANT
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Coffee (Coffea arabica L.) presents antioxidant effects. Due to negative effects of caffeine (Ca), more people consume decaffeinated coffee. Reactive oxygen species are involved in immune cell physiology controlling proliferation, death and cellular metabolism. The aim of this study was to evaluate the influence of Ca in the effect of normal and decaffeinated coffee on normal mice lymphocytes and macrophages. It were assayed MTT, nitroblue tetrazolium reduction, proliferation assays and superoxide and catalase‐like activities were determined. The decaffeinated coffee induced a decrease in lymphocytes proliferation in all concentrations assayed; this effect was related to an increase of superoxide anion and with the absence of Ca, which by itself increased lymphocytes proliferation through a decrease in H2O2 level by CAT activity “per se.” On macrophages, both extracts induced cell activation not related to the presence of Ca. In conclusion, caffeinated coffee could be better than decaffeinated coffee in the maintenance of the oxidative balance in lymphocytes cells.
Fil: Davicino, Roberto Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
description Coffee (Coffea arabica L.) presents antioxidant effects. Due to negative effects of caffeine (Ca), more people consume decaffeinated coffee. Reactive oxygen species are involved in immune cell physiology controlling proliferation, death and cellular metabolism. The aim of this study was to evaluate the influence of Ca in the effect of normal and decaffeinated coffee on normal mice lymphocytes and macrophages. It were assayed MTT, nitroblue tetrazolium reduction, proliferation assays and superoxide and catalase‐like activities were determined. The decaffeinated coffee induced a decrease in lymphocytes proliferation in all concentrations assayed; this effect was related to an increase of superoxide anion and with the absence of Ca, which by itself increased lymphocytes proliferation through a decrease in H2O2 level by CAT activity “per se.” On macrophages, both extracts induced cell activation not related to the presence of Ca. In conclusion, caffeinated coffee could be better than decaffeinated coffee in the maintenance of the oxidative balance in lymphocytes cells.
publishDate 2009
dc.date.none.fl_str_mv 2009-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/115256
Davicino, Roberto Carlos; Alonso, Maria del Rosario; Anesini, Claudia Alejandra; Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine; Wiley Blackwell Publishing, Inc; Journal Of Food Biochemistry; 35; 12-2009; 877-897
0145-8884
CONICET Digital
CONICET
url http://hdl.handle.net/11336/115256
identifier_str_mv Davicino, Roberto Carlos; Alonso, Maria del Rosario; Anesini, Claudia Alejandra; Comparison between normal coffee and decaffeinated coffee effects on lymphocytes and macrophages: role of antioxidant activity of caffeine; Wiley Blackwell Publishing, Inc; Journal Of Food Biochemistry; 35; 12-2009; 877-897
0145-8884
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.onlinelibrary.wiley.com/doi/10.1111/j.1745-4514.2010.00427.x/abstract
info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1745-4514.2010.00427.x/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.48226

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