The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities

Autores
Rabinovich, Gabriel Adrián
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Multiple personality disorder is a psychiatric condition characterized by the spontaneous generation of alternate versions of self. The personalities have distinctive styles of expressing themselves, and they often possess separate names, living locations, and lifestyles. The transition from one personality to another is commonly triggered by environmental and interpersonal factors. Unlike many cellular molecules and pathways, which are often specialized, this concept could be certainly applied to galectins, an evolutionarily conserved family of glycan-binding proteins with multifunctional roles in immunity. These proteins often shuttle between different intracellular compartments (nucleus, cytoplasm, and organelles) and are released to the extracellular milieu, where they acquire different roles in response to diverse microenvironmental stimuli, including hypoxia, nutrient availability, intracellular and extracellular pH, cytokine milieu and the presence of proinflammatory or immunosuppressive signals. ...and more
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Materia
GALECTINS
MULTIFACETES
FUNCTIONS
CYTOKINES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/217592
Acceder
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network_name_str CONICET Digital (CONICET)
spelling The multifaceted roles of galectins: Glycan-binding proteins with multiple personalitiesRabinovich, Gabriel AdriánGALECTINSMULTIFACETESFUNCTIONSCYTOKINEShttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Multiple personality disorder is a psychiatric condition characterized by the spontaneous generation of alternate versions of self. The personalities have distinctive styles of expressing themselves, and they often possess separate names, living locations, and lifestyles. The transition from one personality to another is commonly triggered by environmental and interpersonal factors. Unlike many cellular molecules and pathways, which are often specialized, this concept could be certainly applied to galectins, an evolutionarily conserved family of glycan-binding proteins with multifunctional roles in immunity. These proteins often shuttle between different intracellular compartments (nucleus, cytoplasm, and organelles) and are released to the extracellular milieu, where they acquire different roles in response to diverse microenvironmental stimuli, including hypoxia, nutrient availability, intracellular and extracellular pH, cytokine milieu and the presence of proinflammatory or immunosuppressive signals. ...and moreFil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaSeikagaku Corporation2023-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/217592Rabinovich, Gabriel Adrián; The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities; Seikagaku Corporation; Glycoforum; 26; 4; 8-2023; 1-131349-9416CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.glycoforum.gr.jp/article/26A12.htmlinfo:eu-repo/semantics/altIdentifier/doi/10.32285/glycoforum.26A12info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T11:47:25Zoai:ri.conicet.gov.ar:11336/217592instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 11:47:25.38CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
title The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
spellingShingle The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
Rabinovich, Gabriel Adrián
GALECTINS
MULTIFACETES
FUNCTIONS
CYTOKINES
title_short The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
title_full The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
title_fullStr The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
title_full_unstemmed The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
title_sort The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities
dc.creator.none.fl_str_mv Rabinovich, Gabriel Adrián
author Rabinovich, Gabriel Adrián
author_facet Rabinovich, Gabriel Adrián
author_role author
dc.subject.none.fl_str_mv GALECTINS
MULTIFACETES
FUNCTIONS
CYTOKINES
topic GALECTINS
MULTIFACETES
FUNCTIONS
CYTOKINES
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Multiple personality disorder is a psychiatric condition characterized by the spontaneous generation of alternate versions of self. The personalities have distinctive styles of expressing themselves, and they often possess separate names, living locations, and lifestyles. The transition from one personality to another is commonly triggered by environmental and interpersonal factors. Unlike many cellular molecules and pathways, which are often specialized, this concept could be certainly applied to galectins, an evolutionarily conserved family of glycan-binding proteins with multifunctional roles in immunity. These proteins often shuttle between different intracellular compartments (nucleus, cytoplasm, and organelles) and are released to the extracellular milieu, where they acquire different roles in response to diverse microenvironmental stimuli, including hypoxia, nutrient availability, intracellular and extracellular pH, cytokine milieu and the presence of proinflammatory or immunosuppressive signals. ...and more
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
description Multiple personality disorder is a psychiatric condition characterized by the spontaneous generation of alternate versions of self. The personalities have distinctive styles of expressing themselves, and they often possess separate names, living locations, and lifestyles. The transition from one personality to another is commonly triggered by environmental and interpersonal factors. Unlike many cellular molecules and pathways, which are often specialized, this concept could be certainly applied to galectins, an evolutionarily conserved family of glycan-binding proteins with multifunctional roles in immunity. These proteins often shuttle between different intracellular compartments (nucleus, cytoplasm, and organelles) and are released to the extracellular milieu, where they acquire different roles in response to diverse microenvironmental stimuli, including hypoxia, nutrient availability, intracellular and extracellular pH, cytokine milieu and the presence of proinflammatory or immunosuppressive signals. ...and more
publishDate 2023
dc.date.none.fl_str_mv 2023-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/217592
Rabinovich, Gabriel Adrián; The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities; Seikagaku Corporation; Glycoforum; 26; 4; 8-2023; 1-13
1349-9416
CONICET Digital
CONICET
url http://hdl.handle.net/11336/217592
identifier_str_mv Rabinovich, Gabriel Adrián; The multifaceted roles of galectins: Glycan-binding proteins with multiple personalities; Seikagaku Corporation; Glycoforum; 26; 4; 8-2023; 1-13
1349-9416
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.glycoforum.gr.jp/article/26A12.html
info:eu-repo/semantics/altIdentifier/doi/10.32285/glycoforum.26A12
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Seikagaku Corporation
publisher.none.fl_str_mv Seikagaku Corporation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1843606822872678400
score 13.001348

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