Association between Cancer and Environmental Exposure to Glyphosate

Autores
Avila Vazquez, Medardo; Maturano, Eduardo; Etchegoyen, María Agustina; Difilippo, Flavia Silvina; Maclean, Bryan
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Argentina, Brazil, Paraguay and Uruguay farm transgenic seeds glyphosate resistant. Argentina annually utilizes 240,000 tonnes of glyphosate in agriculture. A change in the profile of morbidity and mortality is perceived in agricultural areas; cancer seems to prevail. Monte Maíz is a typical argentine agricultural town with 8000 inhabitants; the Mayor and residents of Monte Maiz requested an environmental health study due to perceived increase in cancer frequencies. Methods: An exploratory ecological study was developed to assess the urban environmental contamination and the frequencies and distribution of cancer through an environmental analysis of pollution sources including measurements of pesticides in water, soil and grain dust, and a cross-sectional study of cancer patients that explore associations with different variables. Results: Glyphosate was detected in soil and grain dust and was found to be at an even higher concentration in the village soil than in the rural area. 650 tonnes are used annually in the region and manipulated inner town. We do not find other relevant sources of pollution. Cancer incidence, prevalence, and mortality are between two and three times higher than the reference values (Globocan 2012, WHO) for the entire nation (706/100,000 persons vs. 217/100,000; 2123/100,000 persons vs. 883.82/100,000 and 383/100,000 persons vs. 115.13/100,000, respectively). Conclusion: This study detects high glyphosate pollution in association with increased frequencies of cancer in a typical argentine agricultural village, and by design, cannot make claims of causality. Other study designs are required, but if we corroborate the concrescence of high exposure to glyphosate and cancer.
Fil: Avila Vazquez, Medardo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Maturano, Eduardo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Etchegoyen, María Agustina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; Argentina
Fil: Difilippo, Flavia Silvina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Maclean, Bryan. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Materia
GLYPHOSATE
PESTICIDES
ENVIRONMENTAL EXPOSURE
ENVIRONMENTAL HEALTH
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/56435
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Association between Cancer and Environmental Exposure to GlyphosateAvila Vazquez, MedardoMaturano, EduardoEtchegoyen, María AgustinaDifilippo, Flavia SilvinaMaclean, BryanGLYPHOSATEPESTICIDESENVIRONMENTAL EXPOSUREENVIRONMENTAL HEALTHhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Argentina, Brazil, Paraguay and Uruguay farm transgenic seeds glyphosate resistant. Argentina annually utilizes 240,000 tonnes of glyphosate in agriculture. A change in the profile of morbidity and mortality is perceived in agricultural areas; cancer seems to prevail. Monte Maíz is a typical argentine agricultural town with 8000 inhabitants; the Mayor and residents of Monte Maiz requested an environmental health study due to perceived increase in cancer frequencies. Methods: An exploratory ecological study was developed to assess the urban environmental contamination and the frequencies and distribution of cancer through an environmental analysis of pollution sources including measurements of pesticides in water, soil and grain dust, and a cross-sectional study of cancer patients that explore associations with different variables. Results: Glyphosate was detected in soil and grain dust and was found to be at an even higher concentration in the village soil than in the rural area. 650 tonnes are used annually in the region and manipulated inner town. We do not find other relevant sources of pollution. Cancer incidence, prevalence, and mortality are between two and three times higher than the reference values (Globocan 2012, WHO) for the entire nation (706/100,000 persons vs. 217/100,000; 2123/100,000 persons vs. 883.82/100,000 and 383/100,000 persons vs. 115.13/100,000, respectively). Conclusion: This study detects high glyphosate pollution in association with increased frequencies of cancer in a typical argentine agricultural village, and by design, cannot make claims of causality. Other study designs are required, but if we corroborate the concrescence of high exposure to glyphosate and cancer.Fil: Avila Vazquez, Medardo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaFil: Maturano, Eduardo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaFil: Etchegoyen, María Agustina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; ArgentinaFil: Difilippo, Flavia Silvina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaFil: Maclean, Bryan. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaScientific Research Publishing2017-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/56435Avila Vazquez, Medardo ; Maturano, Eduardo; Etchegoyen, María Agustina; Difilippo, Flavia Silvina; Maclean, Bryan; Association between Cancer and Environmental Exposure to Glyphosate; Scientific Research Publishing; International Journal of Clinical Medicine; 8; 2; 2-2017; 73-852158-2882CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.4236/ijcm.2017.82007info:eu-repo/semantics/altIdentifier/url/http://file.scirp.org/Html/2-2101520_74222.htminfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:23:20Zoai:ri.conicet.gov.ar:11336/56435instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:23:20.76CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Association between Cancer and Environmental Exposure to Glyphosate
title Association between Cancer and Environmental Exposure to Glyphosate
spellingShingle Association between Cancer and Environmental Exposure to Glyphosate
Avila Vazquez, Medardo
GLYPHOSATE
PESTICIDES
ENVIRONMENTAL EXPOSURE
ENVIRONMENTAL HEALTH
title_short Association between Cancer and Environmental Exposure to Glyphosate
title_full Association between Cancer and Environmental Exposure to Glyphosate
title_fullStr Association between Cancer and Environmental Exposure to Glyphosate
title_full_unstemmed Association between Cancer and Environmental Exposure to Glyphosate
title_sort Association between Cancer and Environmental Exposure to Glyphosate
dc.creator.none.fl_str_mv Avila Vazquez, Medardo
Maturano, Eduardo
Etchegoyen, María Agustina
Difilippo, Flavia Silvina
Maclean, Bryan
author Avila Vazquez, Medardo
author_facet Avila Vazquez, Medardo
Maturano, Eduardo
Etchegoyen, María Agustina
Difilippo, Flavia Silvina
Maclean, Bryan
author_role author
author2 Maturano, Eduardo
Etchegoyen, María Agustina
Difilippo, Flavia Silvina
Maclean, Bryan
author2_role author
author
author
author
dc.subject.none.fl_str_mv GLYPHOSATE
PESTICIDES
ENVIRONMENTAL EXPOSURE
ENVIRONMENTAL HEALTH
topic GLYPHOSATE
PESTICIDES
ENVIRONMENTAL EXPOSURE
ENVIRONMENTAL HEALTH
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Argentina, Brazil, Paraguay and Uruguay farm transgenic seeds glyphosate resistant. Argentina annually utilizes 240,000 tonnes of glyphosate in agriculture. A change in the profile of morbidity and mortality is perceived in agricultural areas; cancer seems to prevail. Monte Maíz is a typical argentine agricultural town with 8000 inhabitants; the Mayor and residents of Monte Maiz requested an environmental health study due to perceived increase in cancer frequencies. Methods: An exploratory ecological study was developed to assess the urban environmental contamination and the frequencies and distribution of cancer through an environmental analysis of pollution sources including measurements of pesticides in water, soil and grain dust, and a cross-sectional study of cancer patients that explore associations with different variables. Results: Glyphosate was detected in soil and grain dust and was found to be at an even higher concentration in the village soil than in the rural area. 650 tonnes are used annually in the region and manipulated inner town. We do not find other relevant sources of pollution. Cancer incidence, prevalence, and mortality are between two and three times higher than the reference values (Globocan 2012, WHO) for the entire nation (706/100,000 persons vs. 217/100,000; 2123/100,000 persons vs. 883.82/100,000 and 383/100,000 persons vs. 115.13/100,000, respectively). Conclusion: This study detects high glyphosate pollution in association with increased frequencies of cancer in a typical argentine agricultural village, and by design, cannot make claims of causality. Other study designs are required, but if we corroborate the concrescence of high exposure to glyphosate and cancer.
Fil: Avila Vazquez, Medardo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Maturano, Eduardo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Etchegoyen, María Agustina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; Argentina
Fil: Difilippo, Flavia Silvina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Maclean, Bryan. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
description Background: Argentina, Brazil, Paraguay and Uruguay farm transgenic seeds glyphosate resistant. Argentina annually utilizes 240,000 tonnes of glyphosate in agriculture. A change in the profile of morbidity and mortality is perceived in agricultural areas; cancer seems to prevail. Monte Maíz is a typical argentine agricultural town with 8000 inhabitants; the Mayor and residents of Monte Maiz requested an environmental health study due to perceived increase in cancer frequencies. Methods: An exploratory ecological study was developed to assess the urban environmental contamination and the frequencies and distribution of cancer through an environmental analysis of pollution sources including measurements of pesticides in water, soil and grain dust, and a cross-sectional study of cancer patients that explore associations with different variables. Results: Glyphosate was detected in soil and grain dust and was found to be at an even higher concentration in the village soil than in the rural area. 650 tonnes are used annually in the region and manipulated inner town. We do not find other relevant sources of pollution. Cancer incidence, prevalence, and mortality are between two and three times higher than the reference values (Globocan 2012, WHO) for the entire nation (706/100,000 persons vs. 217/100,000; 2123/100,000 persons vs. 883.82/100,000 and 383/100,000 persons vs. 115.13/100,000, respectively). Conclusion: This study detects high glyphosate pollution in association with increased frequencies of cancer in a typical argentine agricultural village, and by design, cannot make claims of causality. Other study designs are required, but if we corroborate the concrescence of high exposure to glyphosate and cancer.
publishDate 2017
dc.date.none.fl_str_mv 2017-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/56435
Avila Vazquez, Medardo ; Maturano, Eduardo; Etchegoyen, María Agustina; Difilippo, Flavia Silvina; Maclean, Bryan; Association between Cancer and Environmental Exposure to Glyphosate; Scientific Research Publishing; International Journal of Clinical Medicine; 8; 2; 2-2017; 73-85
2158-2882
CONICET Digital
CONICET
url http://hdl.handle.net/11336/56435
identifier_str_mv Avila Vazquez, Medardo ; Maturano, Eduardo; Etchegoyen, María Agustina; Difilippo, Flavia Silvina; Maclean, Bryan; Association between Cancer and Environmental Exposure to Glyphosate; Scientific Research Publishing; International Journal of Clinical Medicine; 8; 2; 2-2017; 73-85
2158-2882
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.4236/ijcm.2017.82007
info:eu-repo/semantics/altIdentifier/url/http://file.scirp.org/Html/2-2101520_74222.htm
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
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dc.publisher.none.fl_str_mv Scientific Research Publishing
publisher.none.fl_str_mv Scientific Research Publishing
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instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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