Nanomodification of chitosan microspheres with dendron molecules

Autores
Aldana, Ana Agustina; Strumia, Miriam Cristina; Martinelli, Marisa
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The importance of dendritic structures in biology and medicine lies in their multivalency. Dendrons represent a structural component of the parent dendrimer; they have nano-dimensions and their immobilization on surfaces would lead to structural features within this dimensional range. Novel dendronized surface of chitosan microspheres was prepared by reaction between cross-linked biopolymer and Behera´s or bis Behera´s amine dendrons. According to FTIR analysis, it can be concluded that the dendronization took place; the shape and size were homogeneous and independent of the dendronization, according SEM images. Interactions between dendron-polymer network and hydrophilic / hydrophobic characteristics of the dendron modify the physical properties of the microspheres. The swelling studies of dendronized films at pH 1.2 and 7.4 evidenced the so-called ?dendritic effect?. In addition, the microspheres remained stable for an extended period. The highlights of the present research were to develop nanostructured dendronized surfaces on spheres of polymer supports that seem to be appropriate for biomedical applications. The work aimed at studying the effect of dendronization of the surface on the original properties of chitosan microspheres.
Fil: Aldana, Ana Agustina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina
Fil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina
Fil: Martinelli, Marisa. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina
Materia
Dendronized Polymer
Biomaterials
Quitosan
Nanostructured Surface
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/10011
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/10011
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Nanomodification of chitosan microspheres with dendron moleculesAldana, Ana AgustinaStrumia, Miriam CristinaMartinelli, MarisaDendronized PolymerBiomaterialsQuitosanNanostructured Surfacehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The importance of dendritic structures in biology and medicine lies in their multivalency. Dendrons represent a structural component of the parent dendrimer; they have nano-dimensions and their immobilization on surfaces would lead to structural features within this dimensional range. Novel dendronized surface of chitosan microspheres was prepared by reaction between cross-linked biopolymer and Behera´s or bis Behera´s amine dendrons. According to FTIR analysis, it can be concluded that the dendronization took place; the shape and size were homogeneous and independent of the dendronization, according SEM images. Interactions between dendron-polymer network and hydrophilic / hydrophobic characteristics of the dendron modify the physical properties of the microspheres. The swelling studies of dendronized films at pH 1.2 and 7.4 evidenced the so-called ?dendritic effect?. In addition, the microspheres remained stable for an extended period. The highlights of the present research were to develop nanostructured dendronized surfaces on spheres of polymer supports that seem to be appropriate for biomedical applications. The work aimed at studying the effect of dendronization of the surface on the original properties of chitosan microspheres.Fil: Aldana, Ana Agustina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; ArgentinaFil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); ArgentinaFil: Martinelli, Marisa. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); ArgentinaAmerican Scientific Publishers2013-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/10011Aldana, Ana Agustina; Strumia, Miriam Cristina; Martinelli, Marisa; Nanomodification of chitosan microspheres with dendron molecules; American Scientific Publishers; Journal of Biomaterials and Tissue Engineering; 3; 1; 2-2013; 157-1632157-9083enginfo:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/content/asp/jbte/2013/00000003/00000001/art00013?token=004411afe573d257025702c23446c7c40426f7c2b747c4e724725f7426a0ccf030c7info:eu-repo/semantics/altIdentifier/doi/10.1166/jbt.2013.1075info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:29:06Zoai:ri.conicet.gov.ar:11336/10011instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:29:06.763CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Nanomodification of chitosan microspheres with dendron molecules
title Nanomodification of chitosan microspheres with dendron molecules
spellingShingle Nanomodification of chitosan microspheres with dendron molecules
Aldana, Ana Agustina
Dendronized Polymer
Biomaterials
Quitosan
Nanostructured Surface
title_short Nanomodification of chitosan microspheres with dendron molecules
title_full Nanomodification of chitosan microspheres with dendron molecules
title_fullStr Nanomodification of chitosan microspheres with dendron molecules
title_full_unstemmed Nanomodification of chitosan microspheres with dendron molecules
title_sort Nanomodification of chitosan microspheres with dendron molecules
dc.creator.none.fl_str_mv Aldana, Ana Agustina
Strumia, Miriam Cristina
Martinelli, Marisa
author Aldana, Ana Agustina
author_facet Aldana, Ana Agustina
Strumia, Miriam Cristina
Martinelli, Marisa
author_role author
author2 Strumia, Miriam Cristina
Martinelli, Marisa
author2_role author
author
dc.subject.none.fl_str_mv Dendronized Polymer
Biomaterials
Quitosan
Nanostructured Surface
topic Dendronized Polymer
Biomaterials
Quitosan
Nanostructured Surface
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The importance of dendritic structures in biology and medicine lies in their multivalency. Dendrons represent a structural component of the parent dendrimer; they have nano-dimensions and their immobilization on surfaces would lead to structural features within this dimensional range. Novel dendronized surface of chitosan microspheres was prepared by reaction between cross-linked biopolymer and Behera´s or bis Behera´s amine dendrons. According to FTIR analysis, it can be concluded that the dendronization took place; the shape and size were homogeneous and independent of the dendronization, according SEM images. Interactions between dendron-polymer network and hydrophilic / hydrophobic characteristics of the dendron modify the physical properties of the microspheres. The swelling studies of dendronized films at pH 1.2 and 7.4 evidenced the so-called ?dendritic effect?. In addition, the microspheres remained stable for an extended period. The highlights of the present research were to develop nanostructured dendronized surfaces on spheres of polymer supports that seem to be appropriate for biomedical applications. The work aimed at studying the effect of dendronization of the surface on the original properties of chitosan microspheres.
Fil: Aldana, Ana Agustina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina
Fil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina
Fil: Martinelli, Marisa. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina
description The importance of dendritic structures in biology and medicine lies in their multivalency. Dendrons represent a structural component of the parent dendrimer; they have nano-dimensions and their immobilization on surfaces would lead to structural features within this dimensional range. Novel dendronized surface of chitosan microspheres was prepared by reaction between cross-linked biopolymer and Behera´s or bis Behera´s amine dendrons. According to FTIR analysis, it can be concluded that the dendronization took place; the shape and size were homogeneous and independent of the dendronization, according SEM images. Interactions between dendron-polymer network and hydrophilic / hydrophobic characteristics of the dendron modify the physical properties of the microspheres. The swelling studies of dendronized films at pH 1.2 and 7.4 evidenced the so-called ?dendritic effect?. In addition, the microspheres remained stable for an extended period. The highlights of the present research were to develop nanostructured dendronized surfaces on spheres of polymer supports that seem to be appropriate for biomedical applications. The work aimed at studying the effect of dendronization of the surface on the original properties of chitosan microspheres.
publishDate 2013
dc.date.none.fl_str_mv 2013-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/10011
Aldana, Ana Agustina; Strumia, Miriam Cristina; Martinelli, Marisa; Nanomodification of chitosan microspheres with dendron molecules; American Scientific Publishers; Journal of Biomaterials and Tissue Engineering; 3; 1; 2-2013; 157-163
2157-9083
url http://hdl.handle.net/11336/10011
identifier_str_mv Aldana, Ana Agustina; Strumia, Miriam Cristina; Martinelli, Marisa; Nanomodification of chitosan microspheres with dendron molecules; American Scientific Publishers; Journal of Biomaterials and Tissue Engineering; 3; 1; 2-2013; 157-163
2157-9083
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/content/asp/jbte/2013/00000003/00000001/art00013?token=004411afe573d257025702c23446c7c40426f7c2b747c4e724725f7426a0ccf030c7
info:eu-repo/semantics/altIdentifier/doi/10.1166/jbt.2013.1075
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Scientific Publishers
publisher.none.fl_str_mv American Scientific Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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