Congenital Chagas disease: An update

Autores
Carlier, Yves; Sosa-Estani, Sergio Alejandro; Luquetti, Alejandro O; Buekens, Pierre
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic areas, with variations depending on the region. This presentation aims to focus on and update epidemiological data, research methods, involved factors, control strategy and possible prevention of congenital infection with T. cruzi. Considering that etiological treatment of the child is always effective if performed before one year of age, the diagnosis of infection in pregnant women and their newborns has to become the standard of care and integrated into the surveillance programs of syphilis and human immunodeficiency virus. In addition to the standard tests, polymerase chain reaction performed on blood of neonates of infected mothers one month after birth might improve the diagnosis of congenital infection. Recent data bring out that its transmission can be prevented through treatment of infected women before they become pregnant. The role of parasite genotypes and host genetic factors in parasite transmission and development of infection in foetuses/neonates has to be more investigated in order to better estimate the risk factors and impact on health of congenital infection with T. cruzi.
Fil: Carlier, Yves. Université Libre de Bruxelles; Bélgica. University of Tulane; Estados Unidos
Fil: Sosa-Estani, Sergio Alejandro. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Luquetti, Alejandro O. Universidade Federal de Goiás; Brasil
Fil: Buekens, Pierre. University of Tulane; Estados Unidos
Materia
CONGENITAL CHAGAS DISEASE
CONGENITAL T. CRUZI INFECTION
MATERNAL-FOETAL TRANSMISSION
TRYPANOSOMA CRUZI
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/39809
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Congenital Chagas disease: An updateCarlier, YvesSosa-Estani, Sergio AlejandroLuquetti, Alejandro OBuekens, PierreCONGENITAL CHAGAS DISEASECONGENITAL T. CRUZI INFECTIONMATERNAL-FOETAL TRANSMISSIONTRYPANOSOMA CRUZIhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic areas, with variations depending on the region. This presentation aims to focus on and update epidemiological data, research methods, involved factors, control strategy and possible prevention of congenital infection with T. cruzi. Considering that etiological treatment of the child is always effective if performed before one year of age, the diagnosis of infection in pregnant women and their newborns has to become the standard of care and integrated into the surveillance programs of syphilis and human immunodeficiency virus. In addition to the standard tests, polymerase chain reaction performed on blood of neonates of infected mothers one month after birth might improve the diagnosis of congenital infection. Recent data bring out that its transmission can be prevented through treatment of infected women before they become pregnant. The role of parasite genotypes and host genetic factors in parasite transmission and development of infection in foetuses/neonates has to be more investigated in order to better estimate the risk factors and impact on health of congenital infection with T. cruzi.Fil: Carlier, Yves. Université Libre de Bruxelles; Bélgica. University of Tulane; Estados UnidosFil: Sosa-Estani, Sergio Alejandro. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Luquetti, Alejandro O. Universidade Federal de Goiás; BrasilFil: Buekens, Pierre. University of Tulane; Estados UnidosFundação Oswaldo Cruz2015-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/39809Carlier, Yves; Sosa-Estani, Sergio Alejandro; Luquetti, Alejandro O; Buekens, Pierre; Congenital Chagas disease: An update; Fundação Oswaldo Cruz; Memórias do Instituto Oswaldo Cruz; 110; 3; 5-2015; 363-3680074-02761678-8060CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1590/0074-02760140405info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489473/info:eu-repo/semantics/altIdentifier/url/http://memorias.ioc.fiocruz.br/article/3515/0405_congenital-chagas-disease-an-updateinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:53:32Zoai:ri.conicet.gov.ar:11336/39809instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:53:33.226CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Congenital Chagas disease: An update
title Congenital Chagas disease: An update
spellingShingle Congenital Chagas disease: An update
Carlier, Yves
CONGENITAL CHAGAS DISEASE
CONGENITAL T. CRUZI INFECTION
MATERNAL-FOETAL TRANSMISSION
TRYPANOSOMA CRUZI
title_short Congenital Chagas disease: An update
title_full Congenital Chagas disease: An update
title_fullStr Congenital Chagas disease: An update
title_full_unstemmed Congenital Chagas disease: An update
title_sort Congenital Chagas disease: An update
dc.creator.none.fl_str_mv Carlier, Yves
Sosa-Estani, Sergio Alejandro
Luquetti, Alejandro O
Buekens, Pierre
author Carlier, Yves
author_facet Carlier, Yves
Sosa-Estani, Sergio Alejandro
Luquetti, Alejandro O
Buekens, Pierre
author_role author
author2 Sosa-Estani, Sergio Alejandro
Luquetti, Alejandro O
Buekens, Pierre
author2_role author
author
author
dc.subject.none.fl_str_mv CONGENITAL CHAGAS DISEASE
CONGENITAL T. CRUZI INFECTION
MATERNAL-FOETAL TRANSMISSION
TRYPANOSOMA CRUZI
topic CONGENITAL CHAGAS DISEASE
CONGENITAL T. CRUZI INFECTION
MATERNAL-FOETAL TRANSMISSION
TRYPANOSOMA CRUZI
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic areas, with variations depending on the region. This presentation aims to focus on and update epidemiological data, research methods, involved factors, control strategy and possible prevention of congenital infection with T. cruzi. Considering that etiological treatment of the child is always effective if performed before one year of age, the diagnosis of infection in pregnant women and their newborns has to become the standard of care and integrated into the surveillance programs of syphilis and human immunodeficiency virus. In addition to the standard tests, polymerase chain reaction performed on blood of neonates of infected mothers one month after birth might improve the diagnosis of congenital infection. Recent data bring out that its transmission can be prevented through treatment of infected women before they become pregnant. The role of parasite genotypes and host genetic factors in parasite transmission and development of infection in foetuses/neonates has to be more investigated in order to better estimate the risk factors and impact on health of congenital infection with T. cruzi.
Fil: Carlier, Yves. Université Libre de Bruxelles; Bélgica. University of Tulane; Estados Unidos
Fil: Sosa-Estani, Sergio Alejandro. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Luquetti, Alejandro O. Universidade Federal de Goiás; Brasil
Fil: Buekens, Pierre. University of Tulane; Estados Unidos
description Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic areas, with variations depending on the region. This presentation aims to focus on and update epidemiological data, research methods, involved factors, control strategy and possible prevention of congenital infection with T. cruzi. Considering that etiological treatment of the child is always effective if performed before one year of age, the diagnosis of infection in pregnant women and their newborns has to become the standard of care and integrated into the surveillance programs of syphilis and human immunodeficiency virus. In addition to the standard tests, polymerase chain reaction performed on blood of neonates of infected mothers one month after birth might improve the diagnosis of congenital infection. Recent data bring out that its transmission can be prevented through treatment of infected women before they become pregnant. The role of parasite genotypes and host genetic factors in parasite transmission and development of infection in foetuses/neonates has to be more investigated in order to better estimate the risk factors and impact on health of congenital infection with T. cruzi.
publishDate 2015
dc.date.none.fl_str_mv 2015-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/39809
Carlier, Yves; Sosa-Estani, Sergio Alejandro; Luquetti, Alejandro O; Buekens, Pierre; Congenital Chagas disease: An update; Fundação Oswaldo Cruz; Memórias do Instituto Oswaldo Cruz; 110; 3; 5-2015; 363-368
0074-0276
1678-8060
CONICET Digital
CONICET
url http://hdl.handle.net/11336/39809
identifier_str_mv Carlier, Yves; Sosa-Estani, Sergio Alejandro; Luquetti, Alejandro O; Buekens, Pierre; Congenital Chagas disease: An update; Fundação Oswaldo Cruz; Memórias do Instituto Oswaldo Cruz; 110; 3; 5-2015; 363-368
0074-0276
1678-8060
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1590/0074-02760140405
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489473/
info:eu-repo/semantics/altIdentifier/url/http://memorias.ioc.fiocruz.br/article/3515/0405_congenital-chagas-disease-an-update
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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