Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild

Autores
Palacios, Maria Gabriela; Cunnick, Joan E.; Bronikowski, Anne M.
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The immunocompetence "pace-of-life" hypothesis proposes that fast-living organisms should invest more in innate immune defenses and less in adaptive defenses compared to slow-living ones. We found some support for this hypothesis in two lifehistory ecotypes of the snake Thamnophis elegans; fast-living individuals show higher levels of innate immunity compared to slow-living ones. Here, we optimized a lymphocyte proliferation assay to assess the complementary prediction that slowliving snakes should in turn show stronger adaptive defenses. We also assessed the "environmental" hypothesis that predicts that slow-living snakes should show lower levels of immune defenses (both innate and adaptive) given the harsher environment they live in. Proliferation of B- and T-lymphocytes of free-living individuals was on average higher in fast-living than slow-living snakes, opposing the pace-of-life hypothesis and supporting the environmental hypothesis. Bactericidal capacity of plasma, an index of innate immunity, did not differ between fast-living and slow-living snakes in this study, contrasting the previously documented pattern and highlighting the importance of annual environmental conditions as determinants of immune profiles of free-living animals. Our results do not negate a link between life history and immunity, as indicated by ecotype-specific relationships between lymphocyte proliferation and body condition, but suggest more subtle nuances than those currently proposed.
Fil: Palacios, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina. Iowa State University. Department of Ecology, Evolution and Organismal Biology; Estados Unidos
Fil: Cunnick, Joan E.. Iowa State University. Department of Animal Science; Estados Unidos
Fil: Bronikowski, Anne M.. Iowa State University. Department of Ecology, Evolution and Organismal Biology; Estados Unidos
Materia
Adaptive Immunity
Bacterial Killing
Ecological Immunology
Reptile
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/3462
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/3462
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wildPalacios, Maria GabrielaCunnick, Joan E.Bronikowski, Anne M.Adaptive ImmunityBacterial KillingEcological ImmunologyReptilehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The immunocompetence "pace-of-life" hypothesis proposes that fast-living organisms should invest more in innate immune defenses and less in adaptive defenses compared to slow-living ones. We found some support for this hypothesis in two lifehistory ecotypes of the snake Thamnophis elegans; fast-living individuals show higher levels of innate immunity compared to slow-living ones. Here, we optimized a lymphocyte proliferation assay to assess the complementary prediction that slowliving snakes should in turn show stronger adaptive defenses. We also assessed the "environmental" hypothesis that predicts that slow-living snakes should show lower levels of immune defenses (both innate and adaptive) given the harsher environment they live in. Proliferation of B- and T-lymphocytes of free-living individuals was on average higher in fast-living than slow-living snakes, opposing the pace-of-life hypothesis and supporting the environmental hypothesis. Bactericidal capacity of plasma, an index of innate immunity, did not differ between fast-living and slow-living snakes in this study, contrasting the previously documented pattern and highlighting the importance of annual environmental conditions as determinants of immune profiles of free-living animals. Our results do not negate a link between life history and immunity, as indicated by ecotype-specific relationships between lymphocyte proliferation and body condition, but suggest more subtle nuances than those currently proposed.Fil: Palacios, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina. Iowa State University. Department of Ecology, Evolution and Organismal Biology; Estados UnidosFil: Cunnick, Joan E.. Iowa State University. Department of Animal Science; Estados UnidosFil: Bronikowski, Anne M.. Iowa State University. Department of Ecology, Evolution and Organismal Biology; Estados UnidosUniversity of Chicago Press2013-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/3462Palacios, Maria Gabriela; Cunnick, Joan E.; Bronikowski, Anne M.; Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild; University of Chicago Press; Physiological and Biochemical Zoology; 86; 5; 9-2013; 547-5581522-2152enginfo:eu-repo/semantics/altIdentifier/url/http://www.journals.uchicago.edu/doi/10.1086/672371info:eu-repo/semantics/altIdentifier/doi/10.1086/672371info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:23:18Zoai:ri.conicet.gov.ar:11336/3462instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:23:18.95CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
title Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
spellingShingle Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
Palacios, Maria Gabriela
Adaptive Immunity
Bacterial Killing
Ecological Immunology
Reptile
title_short Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
title_full Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
title_fullStr Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
title_full_unstemmed Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
title_sort Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild
dc.creator.none.fl_str_mv Palacios, Maria Gabriela
Cunnick, Joan E.
Bronikowski, Anne M.
author Palacios, Maria Gabriela
author_facet Palacios, Maria Gabriela
Cunnick, Joan E.
Bronikowski, Anne M.
author_role author
author2 Cunnick, Joan E.
Bronikowski, Anne M.
author2_role author
author
dc.subject.none.fl_str_mv Adaptive Immunity
Bacterial Killing
Ecological Immunology
Reptile
topic Adaptive Immunity
Bacterial Killing
Ecological Immunology
Reptile
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The immunocompetence "pace-of-life" hypothesis proposes that fast-living organisms should invest more in innate immune defenses and less in adaptive defenses compared to slow-living ones. We found some support for this hypothesis in two lifehistory ecotypes of the snake Thamnophis elegans; fast-living individuals show higher levels of innate immunity compared to slow-living ones. Here, we optimized a lymphocyte proliferation assay to assess the complementary prediction that slowliving snakes should in turn show stronger adaptive defenses. We also assessed the "environmental" hypothesis that predicts that slow-living snakes should show lower levels of immune defenses (both innate and adaptive) given the harsher environment they live in. Proliferation of B- and T-lymphocytes of free-living individuals was on average higher in fast-living than slow-living snakes, opposing the pace-of-life hypothesis and supporting the environmental hypothesis. Bactericidal capacity of plasma, an index of innate immunity, did not differ between fast-living and slow-living snakes in this study, contrasting the previously documented pattern and highlighting the importance of annual environmental conditions as determinants of immune profiles of free-living animals. Our results do not negate a link between life history and immunity, as indicated by ecotype-specific relationships between lymphocyte proliferation and body condition, but suggest more subtle nuances than those currently proposed.
Fil: Palacios, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina. Iowa State University. Department of Ecology, Evolution and Organismal Biology; Estados Unidos
Fil: Cunnick, Joan E.. Iowa State University. Department of Animal Science; Estados Unidos
Fil: Bronikowski, Anne M.. Iowa State University. Department of Ecology, Evolution and Organismal Biology; Estados Unidos
description The immunocompetence "pace-of-life" hypothesis proposes that fast-living organisms should invest more in innate immune defenses and less in adaptive defenses compared to slow-living ones. We found some support for this hypothesis in two lifehistory ecotypes of the snake Thamnophis elegans; fast-living individuals show higher levels of innate immunity compared to slow-living ones. Here, we optimized a lymphocyte proliferation assay to assess the complementary prediction that slowliving snakes should in turn show stronger adaptive defenses. We also assessed the "environmental" hypothesis that predicts that slow-living snakes should show lower levels of immune defenses (both innate and adaptive) given the harsher environment they live in. Proliferation of B- and T-lymphocytes of free-living individuals was on average higher in fast-living than slow-living snakes, opposing the pace-of-life hypothesis and supporting the environmental hypothesis. Bactericidal capacity of plasma, an index of innate immunity, did not differ between fast-living and slow-living snakes in this study, contrasting the previously documented pattern and highlighting the importance of annual environmental conditions as determinants of immune profiles of free-living animals. Our results do not negate a link between life history and immunity, as indicated by ecotype-specific relationships between lymphocyte proliferation and body condition, but suggest more subtle nuances than those currently proposed.
publishDate 2013
dc.date.none.fl_str_mv 2013-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/3462
Palacios, Maria Gabriela; Cunnick, Joan E.; Bronikowski, Anne M.; Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild; University of Chicago Press; Physiological and Biochemical Zoology; 86; 5; 9-2013; 547-558
1522-2152
url http://hdl.handle.net/11336/3462
identifier_str_mv Palacios, Maria Gabriela; Cunnick, Joan E.; Bronikowski, Anne M.; Complex interplay of body condition, life history, and prevailing environment shapes immune defenses of garter snakes in the wild; University of Chicago Press; Physiological and Biochemical Zoology; 86; 5; 9-2013; 547-558
1522-2152
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.journals.uchicago.edu/doi/10.1086/672371
info:eu-repo/semantics/altIdentifier/doi/10.1086/672371
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv University of Chicago Press
publisher.none.fl_str_mv University of Chicago Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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