Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: App...

Autores
Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Di Cosimo, Juana Isabel
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A gas chromatography (GC) method for the simultaneous determination of glycerol, methyl oleate, monoglycerides (alpha- and beta-glyceryl monooleates), diglycerides (1,2- and 1,3-glyceryl dioleates), and triglycerides is postulated and validated to monitor the reaction product evolution during the catalytic synthesis of monoglycerides by glycerolysis of methyl oleate. The method is suitable for quantitative analysis of the multiphase reaction system, either under liquid or solid catalyzed conditions in a wide concentration range. Excellent separation of all the analytes was achieved with a 15 m-capillary column of 100% methyl polysiloxane in 35 minutes. A discussion on different solvents (toluene and n-hexane) and derivatization procedures is presented. A proper and unique combination of silylating agents for the trimethylsilylation of the free hydroxyl groups of glycerol, mono- and diglycerides is proposed as well as two internal standards, n-hexadecane and cholesterol. The method accuracy was evaluated from recovery experiments and the precision by repeated analysis of each sample. Relative recoveries of the analytes ranged from 98-105 % and relative standard deviations from 4.8 to 13.0 %. Good linearity of calibration curves was obtained in the investigated concentration ranges with high correlation coefficients (r2 > 0.996) for all the analytes.
Fil: Ferretti, Cristián Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina
Fil: Apesteguia, Carlos Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina
Fil: Di Cosimo, Juana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina
Materia
GLYCEROLYSIS
MONOGLYCERIDES
GAS CHROMATOGRAPHY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/54012
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysisFerretti, Cristián AlejandroApesteguia, Carlos RodolfoDi Cosimo, Juana IsabelGLYCEROLYSISMONOGLYCERIDESGAS CHROMATOGRAPHYhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2A gas chromatography (GC) method for the simultaneous determination of glycerol, methyl oleate, monoglycerides (alpha- and beta-glyceryl monooleates), diglycerides (1,2- and 1,3-glyceryl dioleates), and triglycerides is postulated and validated to monitor the reaction product evolution during the catalytic synthesis of monoglycerides by glycerolysis of methyl oleate. The method is suitable for quantitative analysis of the multiphase reaction system, either under liquid or solid catalyzed conditions in a wide concentration range. Excellent separation of all the analytes was achieved with a 15 m-capillary column of 100% methyl polysiloxane in 35 minutes. A discussion on different solvents (toluene and n-hexane) and derivatization procedures is presented. A proper and unique combination of silylating agents for the trimethylsilylation of the free hydroxyl groups of glycerol, mono- and diglycerides is proposed as well as two internal standards, n-hexadecane and cholesterol. The method accuracy was evaluated from recovery experiments and the precision by repeated analysis of each sample. Relative recoveries of the analytes ranged from 98-105 % and relative standard deviations from 4.8 to 13.0 %. Good linearity of calibration curves was obtained in the investigated concentration ranges with high correlation coefficients (r2 > 0.996) for all the analytes.Fil: Ferretti, Cristián Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; ArgentinaFil: Apesteguia, Carlos Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; ArgentinaFil: Di Cosimo, Juana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; ArgentinaAsociación Química Argentina2011-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/54012Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Di Cosimo, Juana Isabel; Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis; Asociación Química Argentina; Journal of the Argentine Chemical Society; 98; 4-2011; 16-280365-0375CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/images/anales/pdf98/98art3.pdfinfo:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/index.php/volumenes-publicadosinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:29:58Zoai:ri.conicet.gov.ar:11336/54012instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:29:58.209CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
title Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
spellingShingle Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
Ferretti, Cristián Alejandro
GLYCEROLYSIS
MONOGLYCERIDES
GAS CHROMATOGRAPHY
title_short Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
title_full Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
title_fullStr Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
title_full_unstemmed Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
title_sort Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis
dc.creator.none.fl_str_mv Ferretti, Cristián Alejandro
Apesteguia, Carlos Rodolfo
Di Cosimo, Juana Isabel
author Ferretti, Cristián Alejandro
author_facet Ferretti, Cristián Alejandro
Apesteguia, Carlos Rodolfo
Di Cosimo, Juana Isabel
author_role author
author2 Apesteguia, Carlos Rodolfo
Di Cosimo, Juana Isabel
author2_role author
author
dc.subject.none.fl_str_mv GLYCEROLYSIS
MONOGLYCERIDES
GAS CHROMATOGRAPHY
topic GLYCEROLYSIS
MONOGLYCERIDES
GAS CHROMATOGRAPHY
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv A gas chromatography (GC) method for the simultaneous determination of glycerol, methyl oleate, monoglycerides (alpha- and beta-glyceryl monooleates), diglycerides (1,2- and 1,3-glyceryl dioleates), and triglycerides is postulated and validated to monitor the reaction product evolution during the catalytic synthesis of monoglycerides by glycerolysis of methyl oleate. The method is suitable for quantitative analysis of the multiphase reaction system, either under liquid or solid catalyzed conditions in a wide concentration range. Excellent separation of all the analytes was achieved with a 15 m-capillary column of 100% methyl polysiloxane in 35 minutes. A discussion on different solvents (toluene and n-hexane) and derivatization procedures is presented. A proper and unique combination of silylating agents for the trimethylsilylation of the free hydroxyl groups of glycerol, mono- and diglycerides is proposed as well as two internal standards, n-hexadecane and cholesterol. The method accuracy was evaluated from recovery experiments and the precision by repeated analysis of each sample. Relative recoveries of the analytes ranged from 98-105 % and relative standard deviations from 4.8 to 13.0 %. Good linearity of calibration curves was obtained in the investigated concentration ranges with high correlation coefficients (r2 > 0.996) for all the analytes.
Fil: Ferretti, Cristián Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina
Fil: Apesteguia, Carlos Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina
Fil: Di Cosimo, Juana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina
description A gas chromatography (GC) method for the simultaneous determination of glycerol, methyl oleate, monoglycerides (alpha- and beta-glyceryl monooleates), diglycerides (1,2- and 1,3-glyceryl dioleates), and triglycerides is postulated and validated to monitor the reaction product evolution during the catalytic synthesis of monoglycerides by glycerolysis of methyl oleate. The method is suitable for quantitative analysis of the multiphase reaction system, either under liquid or solid catalyzed conditions in a wide concentration range. Excellent separation of all the analytes was achieved with a 15 m-capillary column of 100% methyl polysiloxane in 35 minutes. A discussion on different solvents (toluene and n-hexane) and derivatization procedures is presented. A proper and unique combination of silylating agents for the trimethylsilylation of the free hydroxyl groups of glycerol, mono- and diglycerides is proposed as well as two internal standards, n-hexadecane and cholesterol. The method accuracy was evaluated from recovery experiments and the precision by repeated analysis of each sample. Relative recoveries of the analytes ranged from 98-105 % and relative standard deviations from 4.8 to 13.0 %. Good linearity of calibration curves was obtained in the investigated concentration ranges with high correlation coefficients (r2 > 0.996) for all the analytes.
publishDate 2011
dc.date.none.fl_str_mv 2011-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/54012
Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Di Cosimo, Juana Isabel; Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis; Asociación Química Argentina; Journal of the Argentine Chemical Society; 98; 4-2011; 16-28
0365-0375
CONICET Digital
CONICET
url http://hdl.handle.net/11336/54012
identifier_str_mv Ferretti, Cristián Alejandro; Apesteguia, Carlos Rodolfo; Di Cosimo, Juana Isabel; Development and validation of a gas chromatography method for the simultaneous determination of multicomponents during monoglyceride synthesis by glycerolysis of methyl oleate: Application to homogeneous and heterogeneous catalysis; Asociación Química Argentina; Journal of the Argentine Chemical Society; 98; 4-2011; 16-28
0365-0375
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/images/anales/pdf98/98art3.pdf
info:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/index.php/volumenes-publicados
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Asociación Química Argentina
publisher.none.fl_str_mv Asociación Química Argentina
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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