Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda

Autores
Plem, Silvana Cristina; Carrió, María Josefina; Vaira, Stella Maris; Müller, Diana María; Murguia, Marcelo Cesar
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological activity of these synthesized compounds. For this purpose, derivatives of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles were synthesized from commercially available aryl hydrazines and (ethoxymethylene)malononitrile. Three compounds (A, B, C) were tested for in vitro biological activity; two of them, A [5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile] and B [5-amino-1-(perfluorophenyl)-1H-pyrazole-4-carbonitrile] showed promising activity, particularly the compound A. 
Fil: Plem, Silvana Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Carrió, María Josefina. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Departamento de Matematicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Vaira, Stella Maris. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Departamento de Matematicas; Argentina
Fil: Müller, Diana María. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina
Fil: Murguia, Marcelo Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Materia
Biological Activity
Aminopyrazole
Spodoptera Frugiperda
Polyphagous Lepidopteran.
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/23815
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperdaPlem, Silvana CristinaCarrió, María JosefinaVaira, Stella MarisMüller, Diana MaríaMurguia, Marcelo CesarBiological ActivityAminopyrazoleSpodoptera FrugiperdaPolyphagous Lepidopteran.https://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological activity of these synthesized compounds. For this purpose, derivatives of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles were synthesized from commercially available aryl hydrazines and (ethoxymethylene)malononitrile. Three compounds (A, B, C) were tested for in vitro biological activity; two of them, A [5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile] and B [5-amino-1-(perfluorophenyl)-1H-pyrazole-4-carbonitrile] showed promising activity, particularly the compound A. Fil: Plem, Silvana Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Carrió, María Josefina. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Departamento de Matematicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vaira, Stella Maris. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Departamento de Matematicas; ArgentinaFil: Müller, Diana María. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; ArgentinaFil: Murguia, Marcelo Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaAD Publications2016-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/23815Plem, Silvana Cristina; Carrió, María Josefina; Vaira, Stella Maris; Müller, Diana María; Murguia, Marcelo Cesar; Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda; AD Publications; International Journal of Environmental & Agriculture Research; 2; 4; 4-2016; 88-932454-1850CONICET DigitalCONICETenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:29:22Zoai:ri.conicet.gov.ar:11336/23815instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:29:22.705CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
title Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
spellingShingle Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
Plem, Silvana Cristina
Biological Activity
Aminopyrazole
Spodoptera Frugiperda
Polyphagous Lepidopteran.
title_short Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
title_full Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
title_fullStr Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
title_full_unstemmed Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
title_sort Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda
dc.creator.none.fl_str_mv Plem, Silvana Cristina
Carrió, María Josefina
Vaira, Stella Maris
Müller, Diana María
Murguia, Marcelo Cesar
author Plem, Silvana Cristina
author_facet Plem, Silvana Cristina
Carrió, María Josefina
Vaira, Stella Maris
Müller, Diana María
Murguia, Marcelo Cesar
author_role author
author2 Carrió, María Josefina
Vaira, Stella Maris
Müller, Diana María
Murguia, Marcelo Cesar
author2_role author
author
author
author
dc.subject.none.fl_str_mv Biological Activity
Aminopyrazole
Spodoptera Frugiperda
Polyphagous Lepidopteran.
topic Biological Activity
Aminopyrazole
Spodoptera Frugiperda
Polyphagous Lepidopteran.
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological activity of these synthesized compounds. For this purpose, derivatives of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles were synthesized from commercially available aryl hydrazines and (ethoxymethylene)malononitrile. Three compounds (A, B, C) were tested for in vitro biological activity; two of them, A [5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile] and B [5-amino-1-(perfluorophenyl)-1H-pyrazole-4-carbonitrile] showed promising activity, particularly the compound A. 
Fil: Plem, Silvana Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Carrió, María Josefina. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Departamento de Matematicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Vaira, Stella Maris. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Departamento de Matematicas; Argentina
Fil: Müller, Diana María. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina
Fil: Murguia, Marcelo Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
description Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological activity of these synthesized compounds. For this purpose, derivatives of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles were synthesized from commercially available aryl hydrazines and (ethoxymethylene)malononitrile. Three compounds (A, B, C) were tested for in vitro biological activity; two of them, A [5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile] and B [5-amino-1-(perfluorophenyl)-1H-pyrazole-4-carbonitrile] showed promising activity, particularly the compound A. 
publishDate 2016
dc.date.none.fl_str_mv 2016-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/23815
Plem, Silvana Cristina; Carrió, María Josefina; Vaira, Stella Maris; Müller, Diana María; Murguia, Marcelo Cesar; Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda; AD Publications; International Journal of Environmental & Agriculture Research; 2; 4; 4-2016; 88-93
2454-1850
CONICET Digital
CONICET
url http://hdl.handle.net/11336/23815
identifier_str_mv Plem, Silvana Cristina; Carrió, María Josefina; Vaira, Stella Maris; Müller, Diana María; Murguia, Marcelo Cesar; Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda; AD Publications; International Journal of Environmental & Agriculture Research; 2; 4; 4-2016; 88-93
2454-1850
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv AD Publications
publisher.none.fl_str_mv AD Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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