Low-temperature study of a new nevirapine pseudopolymorph

Autores
Silva, C. C. P. da; Cuffini, Silvia Lucia; Faudone, Sonia Nerina; Ayala, A. P.; Ellena, J.
Año de publicación
2007
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The title compound (systematic name: 11-cyclopropyl-4- methyl-5,11-dihydro-6H-dipyrido[3,2-b:20 ,30 -e][1,4]diazepin-6- one butanol 0.3-solvate), C15H14N4O 0.3C4H9OH, was crystallized in a new triclinic pseudopolymorphic form, a butanol solvate, and the crystal structure determined at 150 K. The molecular conformation of this new form differs from that reported previously, although the main intermolecular hydrogen-bond pattern remains the same. N—H O hydrogen bonds [N O = 2.957 (3) A˚ ] form centrosymmetric dimers and the crystal packing of this new pseudopolymorph generates infinite channels along the b axis.
Fil: Silva, C. C. P. da. Universidade de Sao Paulo; Brasil
Fil: Cuffini, Silvia Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; Argentina
Fil: Faudone, Sonia Nerina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; Argentina
Fil: Ayala, A. P.. Universidade Estadual do Ceará; Brasil
Fil: Ellena, J.. Universidade de Sao Paulo; Brasil
Materia
Nevirapine
Low-temperature
New nevirapine pseudopolymorph
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/241225
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/241225
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Low-temperature study of a new nevirapine pseudopolymorphSilva, C. C. P. daCuffini, Silvia LuciaFaudone, Sonia NerinaAyala, A. P.Ellena, J.NevirapineLow-temperatureNew nevirapine pseudopolymorphhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1The title compound (systematic name: 11-cyclopropyl-4- methyl-5,11-dihydro-6H-dipyrido[3,2-b:20 ,30 -e][1,4]diazepin-6- one butanol 0.3-solvate), C15H14N4O 0.3C4H9OH, was crystallized in a new triclinic pseudopolymorphic form, a butanol solvate, and the crystal structure determined at 150 K. The molecular conformation of this new form differs from that reported previously, although the main intermolecular hydrogen-bond pattern remains the same. N—H O hydrogen bonds [N O = 2.957 (3) A˚ ] form centrosymmetric dimers and the crystal packing of this new pseudopolymorph generates infinite channels along the b axis.Fil: Silva, C. C. P. da. Universidade de Sao Paulo; BrasilFil: Cuffini, Silvia Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; ArgentinaFil: Faudone, Sonia Nerina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; ArgentinaFil: Ayala, A. P.. Universidade Estadual do Ceará; BrasilFil: Ellena, J.. Universidade de Sao Paulo; BrasilWiley Blackwell Publishing, Inc2007-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/241225Silva, C. C. P. da; Cuffini, Silvia Lucia; Faudone, Sonia Nerina; Ayala, A. P.; Ellena, J.; Low-temperature study of a new nevirapine pseudopolymorph; Wiley Blackwell Publishing, Inc; Acta Crystallographica Section E; 64; 1; 12-2007; 292-2921600-5368CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.iucr.org/e/issues/2008/01/00/bg2093/index.htmlinfo:eu-repo/semantics/altIdentifier/doi/10.1107/S1600536807042262info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:44:42Zoai:ri.conicet.gov.ar:11336/241225instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:44:42.487CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Low-temperature study of a new nevirapine pseudopolymorph
title Low-temperature study of a new nevirapine pseudopolymorph
spellingShingle Low-temperature study of a new nevirapine pseudopolymorph
Silva, C. C. P. da
Nevirapine
Low-temperature
New nevirapine pseudopolymorph
title_short Low-temperature study of a new nevirapine pseudopolymorph
title_full Low-temperature study of a new nevirapine pseudopolymorph
title_fullStr Low-temperature study of a new nevirapine pseudopolymorph
title_full_unstemmed Low-temperature study of a new nevirapine pseudopolymorph
title_sort Low-temperature study of a new nevirapine pseudopolymorph
dc.creator.none.fl_str_mv Silva, C. C. P. da
Cuffini, Silvia Lucia
Faudone, Sonia Nerina
Ayala, A. P.
Ellena, J.
author Silva, C. C. P. da
author_facet Silva, C. C. P. da
Cuffini, Silvia Lucia
Faudone, Sonia Nerina
Ayala, A. P.
Ellena, J.
author_role author
author2 Cuffini, Silvia Lucia
Faudone, Sonia Nerina
Ayala, A. P.
Ellena, J.
author2_role author
author
author
author
dc.subject.none.fl_str_mv Nevirapine
Low-temperature
New nevirapine pseudopolymorph
topic Nevirapine
Low-temperature
New nevirapine pseudopolymorph
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The title compound (systematic name: 11-cyclopropyl-4- methyl-5,11-dihydro-6H-dipyrido[3,2-b:20 ,30 -e][1,4]diazepin-6- one butanol 0.3-solvate), C15H14N4O 0.3C4H9OH, was crystallized in a new triclinic pseudopolymorphic form, a butanol solvate, and the crystal structure determined at 150 K. The molecular conformation of this new form differs from that reported previously, although the main intermolecular hydrogen-bond pattern remains the same. N—H O hydrogen bonds [N O = 2.957 (3) A˚ ] form centrosymmetric dimers and the crystal packing of this new pseudopolymorph generates infinite channels along the b axis.
Fil: Silva, C. C. P. da. Universidade de Sao Paulo; Brasil
Fil: Cuffini, Silvia Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; Argentina
Fil: Faudone, Sonia Nerina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; Argentina
Fil: Ayala, A. P.. Universidade Estadual do Ceará; Brasil
Fil: Ellena, J.. Universidade de Sao Paulo; Brasil
description The title compound (systematic name: 11-cyclopropyl-4- methyl-5,11-dihydro-6H-dipyrido[3,2-b:20 ,30 -e][1,4]diazepin-6- one butanol 0.3-solvate), C15H14N4O 0.3C4H9OH, was crystallized in a new triclinic pseudopolymorphic form, a butanol solvate, and the crystal structure determined at 150 K. The molecular conformation of this new form differs from that reported previously, although the main intermolecular hydrogen-bond pattern remains the same. N—H O hydrogen bonds [N O = 2.957 (3) A˚ ] form centrosymmetric dimers and the crystal packing of this new pseudopolymorph generates infinite channels along the b axis.
publishDate 2007
dc.date.none.fl_str_mv 2007-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/241225
Silva, C. C. P. da; Cuffini, Silvia Lucia; Faudone, Sonia Nerina; Ayala, A. P.; Ellena, J.; Low-temperature study of a new nevirapine pseudopolymorph; Wiley Blackwell Publishing, Inc; Acta Crystallographica Section E; 64; 1; 12-2007; 292-292
1600-5368
CONICET Digital
CONICET
url http://hdl.handle.net/11336/241225
identifier_str_mv Silva, C. C. P. da; Cuffini, Silvia Lucia; Faudone, Sonia Nerina; Ayala, A. P.; Ellena, J.; Low-temperature study of a new nevirapine pseudopolymorph; Wiley Blackwell Publishing, Inc; Acta Crystallographica Section E; 64; 1; 12-2007; 292-292
1600-5368
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.iucr.org/e/issues/2008/01/00/bg2093/index.html
info:eu-repo/semantics/altIdentifier/doi/10.1107/S1600536807042262
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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