A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised...

Autores: Althabe, Fernando; Chomba, Elwyn; Tshefu, Antoinette K; Banda, Ernest; Belizán, María Melina Eleonora; Bergel, Eduardo; Berrueta, Amanda Mabel; Bertrand, Jane; Bose, Carl; Cafferata, Maria Luisa; Carlo, Waldemar A; Ciganda, Alvaro; Donnay, France; Garcia Elorrio, Ezequiel; Gibbons, Luz; Klein, Karen; Liljestrand, Jerker; Lusamba, Paul D; Mavila, Arlette K; Mazzoni, Agustina; Nkamba, Dalau M; Mwanakalanga, Friday H; Mwapule Tembo, Abigail; Mwenechanya, Musaku; Pyne Mercier, Lee; Spira, Cintia; Wetshikoy, Jean D; Xiong, Xu; Buekens, Pierre
Año de publicación: 2019
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: Background: Despite international recommendations, coverage of syphilis testing in pregnant women and treatment of those found seropositive remains limited in sub-Saharan Africa. We assessed whether combining the provision of supplies with a behavioural intervention was more effective than providing supplies only, to improve syphilis screening and treatment during antenatal care. Methods: In this 18-month, cluster randomised controlled trial, we randomly assigned (1:1) 26 urban antenatal care clinics in Kinshasa, Democratic Republic of the Congo, and Lusaka, Zambia, to receive a behavioural intervention (opinion leader selection, academic detailing visits, reminders, audits and feedback, and supportive supervision) plus supplies for syphilis testing and treatment (intervention group) or to receive supplies only (control group). The primary outcomes were proportion of pregnant women who had syphilis screening out of the total who attended the clinic; and the proportion of women who had treatment with benzathine benzylpenicillin out of those who tested positive for syphilis at their first antenatal care visit. This trial is registered at ClinicalTrials.gov, number NCT02353117. Findings: The 18-month study period was Feb 1, 2016, to July 14, 2017. 18 357 women were enrolled at the 13 intervention clinics and 17 679 women were enrolled at the 13 control clinics at their first antenatal care visit. Syphilis screening was done in a median of 99·9% (IQR 99·0–100·0) of women in the intervention clinics and 93·8% (85·0–98·9) in the control clinics (absolute difference 6·1% [95% CI 1·1–14·1]; p=0·00092). Syphilis treatment at the first visit was done in a median of 100% (IQR 99·7–100·0) of seropositive women in intervention clinics and 43·2% (2·6–83·2) of seropositive women in control clinics (absolute difference 56·8% [12·8–99·0]; p=0·0028). Interpretation: A behavioural intervention, together with the provision of supplies, can lead to more than 95% of women being screened and treated for syphilis. The sole provision of supplies is sufficient to reach such levels of screening coverage but is not sufficient to ensure high levels of treatment. Funding: Bill & Melinda Gates Foundation.
Fil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina. Organizacion Mundial de la Salud; Argentina
Fil: Chomba, Elwyn. University Teaching Hospital of Lusaka; Zambia
Fil: Tshefu, Antoinette K. University of Kinshasa; República Democrática del Congo
Fil: Banda, Ernest. University Teaching Hospital of Lusaka; Zambia
Fil: Belizán, María Melina Eleonora. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Bergel, Eduardo. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Berrueta, Amanda Mabel. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Bertrand, Jane. University of Tulane; Estados Unidos
Fil: Bose, Carl. University of North Carolina; Estados Unidos
Fil: Cafferata, Maria Luisa. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Carlo, Waldemar A. University of Alabama at Birmingahm; Estados Unidos
Fil: Ciganda, Alvaro. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Donnay, France. University of Tulane; Estados Unidos
Fil: Garcia Elorrio, Ezequiel. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Klein, Karen. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Liljestrand, Jerker. Bill And Melinda Gates Foundation; Estados Unidos
Fil: Lusamba, Paul D. University of Kinshasa; República Democrática del Congo
Fil: Mavila, Arlette K. University of Kinshasa; República Democrática del Congo
Fil: Mazzoni, Agustina. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Nkamba, Dalau M. University of Kinshasa; República Democrática del Congo
Fil: Mwanakalanga, Friday H. University Teaching Hospital Lusaka; Zambia
Fil: Mwapule Tembo, Abigail. University Teaching Hospital Lusaka; Zambia
Fil: Mwenechanya, Musaku. University Teaching Hospital Lusaka; Zambia
Fil: Pyne Mercier, Lee. Bill And Melinda Gates Foundation; Estados Unidos
Fil: Spira, Cintia. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Wetshikoy, Jean D. University of Kinshasa; República Democrática del Congo
Fil: Xiong, Xu. University of Tulane; Estados Unidos
Fil: Buekens, Pierre. University of Tulane; Estados Unidos
Materia: Syphilis
Pregnant women
Democratic Republic of the Congo
Zambia
Nivel de accesibilidad: acceso abierto
Condiciones de uso: https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
Institución: Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador: oai:ri.conicet.gov.ar:11336/135420

Acceder

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repository_id_str	3498
network_name_str	CONICET Digital (CONICET)
spelling	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trialAlthabe, FernandoChomba, ElwynTshefu, Antoinette KBanda, ErnestBelizán, María Melina EleonoraBergel, EduardoBerrueta, Amanda MabelBertrand, JaneBose, CarlCafferata, Maria LuisaCarlo, Waldemar ACiganda, AlvaroDonnay, FranceGarcia Elorrio, EzequielGibbons, LuzKlein, KarenLiljestrand, JerkerLusamba, Paul DMavila, Arlette KMazzoni, AgustinaNkamba, Dalau MMwanakalanga, Friday HMwapule Tembo, AbigailMwenechanya, MusakuPyne Mercier, LeeSpira, CintiaWetshikoy, Jean DXiong, XuBuekens, PierreSyphilisPregnant womenDemocratic Republic of the CongoZambiahttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Despite international recommendations, coverage of syphilis testing in pregnant women and treatment of those found seropositive remains limited in sub-Saharan Africa. We assessed whether combining the provision of supplies with a behavioural intervention was more effective than providing supplies only, to improve syphilis screening and treatment during antenatal care. Methods: In this 18-month, cluster randomised controlled trial, we randomly assigned (1:1) 26 urban antenatal care clinics in Kinshasa, Democratic Republic of the Congo, and Lusaka, Zambia, to receive a behavioural intervention (opinion leader selection, academic detailing visits, reminders, audits and feedback, and supportive supervision) plus supplies for syphilis testing and treatment (intervention group) or to receive supplies only (control group). The primary outcomes were proportion of pregnant women who had syphilis screening out of the total who attended the clinic; and the proportion of women who had treatment with benzathine benzylpenicillin out of those who tested positive for syphilis at their first antenatal care visit. This trial is registered at ClinicalTrials.gov, number NCT02353117. Findings: The 18-month study period was Feb 1, 2016, to July 14, 2017. 18 357 women were enrolled at the 13 intervention clinics and 17 679 women were enrolled at the 13 control clinics at their first antenatal care visit. Syphilis screening was done in a median of 99·9% (IQR 99·0–100·0) of women in the intervention clinics and 93·8% (85·0–98·9) in the control clinics (absolute difference 6·1% [95% CI 1·1–14·1]; p=0·00092). Syphilis treatment at the first visit was done in a median of 100% (IQR 99·7–100·0) of seropositive women in intervention clinics and 43·2% (2·6–83·2) of seropositive women in control clinics (absolute difference 56·8% [12·8–99·0]; p=0·0028). Interpretation: A behavioural intervention, together with the provision of supplies, can lead to more than 95% of women being screened and treated for syphilis. The sole provision of supplies is sufficient to reach such levels of screening coverage but is not sufficient to ensure high levels of treatment. Funding: Bill & Melinda Gates Foundation.Fil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina. Organizacion Mundial de la Salud; ArgentinaFil: Chomba, Elwyn. University Teaching Hospital of Lusaka; ZambiaFil: Tshefu, Antoinette K. University of Kinshasa; República Democrática del CongoFil: Banda, Ernest. University Teaching Hospital of Lusaka; ZambiaFil: Belizán, María Melina Eleonora. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bergel, Eduardo. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Berrueta, Amanda Mabel. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Bertrand, Jane. University of Tulane; Estados UnidosFil: Bose, Carl. University of North Carolina; Estados UnidosFil: Cafferata, Maria Luisa. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Carlo, Waldemar A. University of Alabama at Birmingahm; Estados UnidosFil: Ciganda, Alvaro. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Donnay, France. University of Tulane; Estados UnidosFil: Garcia Elorrio, Ezequiel. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Klein, Karen. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Liljestrand, Jerker. Bill And Melinda Gates Foundation; Estados UnidosFil: Lusamba, Paul D. University of Kinshasa; República Democrática del CongoFil: Mavila, Arlette K. University of Kinshasa; República Democrática del CongoFil: Mazzoni, Agustina. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Nkamba, Dalau M. University of Kinshasa; República Democrática del CongoFil: Mwanakalanga, Friday H. University Teaching Hospital Lusaka; ZambiaFil: Mwapule Tembo, Abigail. University Teaching Hospital Lusaka; ZambiaFil: Mwenechanya, Musaku. University Teaching Hospital Lusaka; ZambiaFil: Pyne Mercier, Lee. Bill And Melinda Gates Foundation; Estados UnidosFil: Spira, Cintia. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Wetshikoy, Jean D. University of Kinshasa; República Democrática del CongoFil: Xiong, Xu. University of Tulane; Estados UnidosFil: Buekens, Pierre. University of Tulane; Estados UnidosElsevier2019-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/135420Althabe, Fernando; Chomba, Elwyn; Tshefu, Antoinette K; Banda, Ernest; Belizán, María Melina Eleonora; et al.; A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial; Elsevier; The Lancet Global Health; 7; 5; 5-2019; e655-e6632214-109XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465956/info:eu-repo/semantics/altIdentifier/doi/10.1016/S2214-109X(19)30075-0info:eu-repo/semantics/altIdentifier/url/https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(19)30075-0/fulltextinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:22:56Zoai:ri.conicet.gov.ar:11336/135420instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:22:56.61CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
title	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
spellingShingle	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial Althabe, Fernando Syphilis Pregnant women Democratic Republic of the Congo Zambia
title_short	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
title_full	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
title_fullStr	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
title_full_unstemmed	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
title_sort	A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial
dc.creator.none.fl_str_mv	Althabe, Fernando Chomba, Elwyn Tshefu, Antoinette K Banda, Ernest Belizán, María Melina Eleonora Bergel, Eduardo Berrueta, Amanda Mabel Bertrand, Jane Bose, Carl Cafferata, Maria Luisa Carlo, Waldemar A Ciganda, Alvaro Donnay, France Garcia Elorrio, Ezequiel Gibbons, Luz Klein, Karen Liljestrand, Jerker Lusamba, Paul D Mavila, Arlette K Mazzoni, Agustina Nkamba, Dalau M Mwanakalanga, Friday H Mwapule Tembo, Abigail Mwenechanya, Musaku Pyne Mercier, Lee Spira, Cintia Wetshikoy, Jean D Xiong, Xu Buekens, Pierre
author	Althabe, Fernando
author_facet	Althabe, Fernando Chomba, Elwyn Tshefu, Antoinette K Banda, Ernest Belizán, María Melina Eleonora Bergel, Eduardo Berrueta, Amanda Mabel Bertrand, Jane Bose, Carl Cafferata, Maria Luisa Carlo, Waldemar A Ciganda, Alvaro Donnay, France Garcia Elorrio, Ezequiel Gibbons, Luz Klein, Karen Liljestrand, Jerker Lusamba, Paul D Mavila, Arlette K Mazzoni, Agustina Nkamba, Dalau M Mwanakalanga, Friday H Mwapule Tembo, Abigail Mwenechanya, Musaku Pyne Mercier, Lee Spira, Cintia Wetshikoy, Jean D Xiong, Xu Buekens, Pierre
author_role	author
author2	Chomba, Elwyn Tshefu, Antoinette K Banda, Ernest Belizán, María Melina Eleonora Bergel, Eduardo Berrueta, Amanda Mabel Bertrand, Jane Bose, Carl Cafferata, Maria Luisa Carlo, Waldemar A Ciganda, Alvaro Donnay, France Garcia Elorrio, Ezequiel Gibbons, Luz Klein, Karen Liljestrand, Jerker Lusamba, Paul D Mavila, Arlette K Mazzoni, Agustina Nkamba, Dalau M Mwanakalanga, Friday H Mwapule Tembo, Abigail Mwenechanya, Musaku Pyne Mercier, Lee Spira, Cintia Wetshikoy, Jean D Xiong, Xu Buekens, Pierre
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	Syphilis Pregnant women Democratic Republic of the Congo Zambia
topic	Syphilis Pregnant women Democratic Republic of the Congo Zambia
purl_subject.fl_str_mv	https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv	Background: Despite international recommendations, coverage of syphilis testing in pregnant women and treatment of those found seropositive remains limited in sub-Saharan Africa. We assessed whether combining the provision of supplies with a behavioural intervention was more effective than providing supplies only, to improve syphilis screening and treatment during antenatal care. Methods: In this 18-month, cluster randomised controlled trial, we randomly assigned (1:1) 26 urban antenatal care clinics in Kinshasa, Democratic Republic of the Congo, and Lusaka, Zambia, to receive a behavioural intervention (opinion leader selection, academic detailing visits, reminders, audits and feedback, and supportive supervision) plus supplies for syphilis testing and treatment (intervention group) or to receive supplies only (control group). The primary outcomes were proportion of pregnant women who had syphilis screening out of the total who attended the clinic; and the proportion of women who had treatment with benzathine benzylpenicillin out of those who tested positive for syphilis at their first antenatal care visit. This trial is registered at ClinicalTrials.gov, number NCT02353117. Findings: The 18-month study period was Feb 1, 2016, to July 14, 2017. 18 357 women were enrolled at the 13 intervention clinics and 17 679 women were enrolled at the 13 control clinics at their first antenatal care visit. Syphilis screening was done in a median of 99·9% (IQR 99·0–100·0) of women in the intervention clinics and 93·8% (85·0–98·9) in the control clinics (absolute difference 6·1% [95% CI 1·1–14·1]; p=0·00092). Syphilis treatment at the first visit was done in a median of 100% (IQR 99·7–100·0) of seropositive women in intervention clinics and 43·2% (2·6–83·2) of seropositive women in control clinics (absolute difference 56·8% [12·8–99·0]; p=0·0028). Interpretation: A behavioural intervention, together with the provision of supplies, can lead to more than 95% of women being screened and treated for syphilis. The sole provision of supplies is sufficient to reach such levels of screening coverage but is not sufficient to ensure high levels of treatment. Funding: Bill & Melinda Gates Foundation. Fil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina. Organizacion Mundial de la Salud; Argentina Fil: Chomba, Elwyn. University Teaching Hospital of Lusaka; Zambia Fil: Tshefu, Antoinette K. University of Kinshasa; República Democrática del Congo Fil: Banda, Ernest. University Teaching Hospital of Lusaka; Zambia Fil: Belizán, María Melina Eleonora. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Bergel, Eduardo. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Berrueta, Amanda Mabel. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Bertrand, Jane. University of Tulane; Estados Unidos Fil: Bose, Carl. University of North Carolina; Estados Unidos Fil: Cafferata, Maria Luisa. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Carlo, Waldemar A. University of Alabama at Birmingahm; Estados Unidos Fil: Ciganda, Alvaro. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Donnay, France. University of Tulane; Estados Unidos Fil: Garcia Elorrio, Ezequiel. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Klein, Karen. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Liljestrand, Jerker. Bill And Melinda Gates Foundation; Estados Unidos Fil: Lusamba, Paul D. University of Kinshasa; República Democrática del Congo Fil: Mavila, Arlette K. University of Kinshasa; República Democrática del Congo Fil: Mazzoni, Agustina. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Nkamba, Dalau M. University of Kinshasa; República Democrática del Congo Fil: Mwanakalanga, Friday H. University Teaching Hospital Lusaka; Zambia Fil: Mwapule Tembo, Abigail. University Teaching Hospital Lusaka; Zambia Fil: Mwenechanya, Musaku. University Teaching Hospital Lusaka; Zambia Fil: Pyne Mercier, Lee. Bill And Melinda Gates Foundation; Estados Unidos Fil: Spira, Cintia. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Wetshikoy, Jean D. University of Kinshasa; República Democrática del Congo Fil: Xiong, Xu. University of Tulane; Estados Unidos Fil: Buekens, Pierre. University of Tulane; Estados Unidos
description	Background: Despite international recommendations, coverage of syphilis testing in pregnant women and treatment of those found seropositive remains limited in sub-Saharan Africa. We assessed whether combining the provision of supplies with a behavioural intervention was more effective than providing supplies only, to improve syphilis screening and treatment during antenatal care. Methods: In this 18-month, cluster randomised controlled trial, we randomly assigned (1:1) 26 urban antenatal care clinics in Kinshasa, Democratic Republic of the Congo, and Lusaka, Zambia, to receive a behavioural intervention (opinion leader selection, academic detailing visits, reminders, audits and feedback, and supportive supervision) plus supplies for syphilis testing and treatment (intervention group) or to receive supplies only (control group). The primary outcomes were proportion of pregnant women who had syphilis screening out of the total who attended the clinic; and the proportion of women who had treatment with benzathine benzylpenicillin out of those who tested positive for syphilis at their first antenatal care visit. This trial is registered at ClinicalTrials.gov, number NCT02353117. Findings: The 18-month study period was Feb 1, 2016, to July 14, 2017. 18 357 women were enrolled at the 13 intervention clinics and 17 679 women were enrolled at the 13 control clinics at their first antenatal care visit. Syphilis screening was done in a median of 99·9% (IQR 99·0–100·0) of women in the intervention clinics and 93·8% (85·0–98·9) in the control clinics (absolute difference 6·1% [95% CI 1·1–14·1]; p=0·00092). Syphilis treatment at the first visit was done in a median of 100% (IQR 99·7–100·0) of seropositive women in intervention clinics and 43·2% (2·6–83·2) of seropositive women in control clinics (absolute difference 56·8% [12·8–99·0]; p=0·0028). Interpretation: A behavioural intervention, together with the provision of supplies, can lead to more than 95% of women being screened and treated for syphilis. The sole provision of supplies is sufficient to reach such levels of screening coverage but is not sufficient to ensure high levels of treatment. Funding: Bill & Melinda Gates Foundation.
publishDate	2019
dc.date.none.fl_str_mv	2019-05
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/11336/135420 Althabe, Fernando; Chomba, Elwyn; Tshefu, Antoinette K; Banda, Ernest; Belizán, María Melina Eleonora; et al.; A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial; Elsevier; The Lancet Global Health; 7; 5; 5-2019; e655-e663 2214-109X CONICET Digital CONICET
url	http://hdl.handle.net/11336/135420
identifier_str_mv	Althabe, Fernando; Chomba, Elwyn; Tshefu, Antoinette K; Banda, Ernest; Belizán, María Melina Eleonora; et al.; A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised controlled trial; Elsevier; The Lancet Global Health; 7; 5; 5-2019; e655-e663 2214-109X CONICET Digital CONICET
dc.language.none.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465956/ info:eu-repo/semantics/altIdentifier/doi/10.1016/S2214-109X(19)30075-0 info:eu-repo/semantics/altIdentifier/url/https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(19)30075-0/fulltext
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv	openAccess
rights_invalid_str_mv	https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv	application/pdf application/pdf application/pdf application/pdf
dc.publisher.none.fl_str_mv	Elsevier
publisher.none.fl_str_mv	Elsevier
dc.source.none.fl_str_mv	reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str	CONICET Digital (CONICET)
collection	CONICET Digital (CONICET)
instname_str	Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv	CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv	dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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A multifaceted intervention to improve syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cluster randomised...

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