Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4

Autores
Sookoian, Silvia Cristina; Burgueño, Adriana Laura; Fernandez Gianotti, Tomas; Marillet, Guillermo; Pirola, Carlos Jose
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We performed a study on a sample of 856 individuals to answer whether the pleasantness/unpleasantness of the odor perception of their partners (rating of partner odor) is associated with depression and anxiety. To evaluate the influence of common genetic variation of the odorant receptor OR7D4 on the rating of partner odor, the variant rs8109935 was genotyped in the whole sample. The rating of partner odor was significantly associated with scores of anxiety and depression. Depression (OR: 0.75, 95%CI: 0.56–0.98, p = 0.039) and anxiety (Robust Coef ± SE: −13 ± 0.6, p = 0.044) were inversely associated with pleasantness rating of partner odor. Ordered probit regression analysis shows that the rating of partner odor was significantly associated with the rs8109935 genotypes (Coef ± robust SE: 0.19 ± 0.09, p = 0.028). These findings suggest that odor perception between heterosexual partners may have an impact on the development of depression and anxiety, and that it might be influenced by genetic variation in OR7D4.
Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Burgueño, Adriana Laura. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina
Fil: Fernandez Gianotti, Tomas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina
Fil: Marillet, Guillermo.
Fil: Pirola, Carlos Jose. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina
Materia
Depression
Anxiety
Odor Perception
Odorant Receptor
Or7d4
Gene
Genetics
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/14974
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/14974
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4Sookoian, Silvia CristinaBurgueño, Adriana LauraFernandez Gianotti, TomasMarillet, GuillermoPirola, Carlos JoseDepressionAnxietyOdor PerceptionOdorant ReceptorOr7d4GeneGeneticshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3We performed a study on a sample of 856 individuals to answer whether the pleasantness/unpleasantness of the odor perception of their partners (rating of partner odor) is associated with depression and anxiety. To evaluate the influence of common genetic variation of the odorant receptor OR7D4 on the rating of partner odor, the variant rs8109935 was genotyped in the whole sample. The rating of partner odor was significantly associated with scores of anxiety and depression. Depression (OR: 0.75, 95%CI: 0.56–0.98, p = 0.039) and anxiety (Robust Coef ± SE: −13 ± 0.6, p = 0.044) were inversely associated with pleasantness rating of partner odor. Ordered probit regression analysis shows that the rating of partner odor was significantly associated with the rs8109935 genotypes (Coef ± robust SE: 0.19 ± 0.09, p = 0.028). These findings suggest that odor perception between heterosexual partners may have an impact on the development of depression and anxiety, and that it might be influenced by genetic variation in OR7D4.Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Burgueño, Adriana Laura. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; ArgentinaFil: Fernandez Gianotti, Tomas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; ArgentinaFil: Marillet, Guillermo.Fil: Pirola, Carlos Jose. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; ArgentinaElsevier Science2011-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14974Sookoian, Silvia Cristina; Burgueño, Adriana Laura; Fernandez Gianotti, Tomas; Marillet, Guillermo; Pirola, Carlos Jose; Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4; Elsevier Science; Biological Psychology; 86; 3; 3-2011; 153-1570301-0511enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0301051110003005info:eu-repo/semantics/altIdentifier/doi/10.1016/j.biopsycho.2010.11.003info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-12-23T13:48:39Zoai:ri.conicet.gov.ar:11336/14974instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-12-23 13:48:39.827CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
title Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
spellingShingle Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
Sookoian, Silvia Cristina
Depression
Anxiety
Odor Perception
Odorant Receptor
Or7d4
Gene
Genetics
title_short Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
title_full Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
title_fullStr Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
title_full_unstemmed Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
title_sort Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4
dc.creator.none.fl_str_mv Sookoian, Silvia Cristina
Burgueño, Adriana Laura
Fernandez Gianotti, Tomas
Marillet, Guillermo
Pirola, Carlos Jose
author Sookoian, Silvia Cristina
author_facet Sookoian, Silvia Cristina
Burgueño, Adriana Laura
Fernandez Gianotti, Tomas
Marillet, Guillermo
Pirola, Carlos Jose
author_role author
author2 Burgueño, Adriana Laura
Fernandez Gianotti, Tomas
Marillet, Guillermo
Pirola, Carlos Jose
author2_role author
author
author
author
dc.subject.none.fl_str_mv Depression
Anxiety
Odor Perception
Odorant Receptor
Or7d4
Gene
Genetics
topic Depression
Anxiety
Odor Perception
Odorant Receptor
Or7d4
Gene
Genetics
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv We performed a study on a sample of 856 individuals to answer whether the pleasantness/unpleasantness of the odor perception of their partners (rating of partner odor) is associated with depression and anxiety. To evaluate the influence of common genetic variation of the odorant receptor OR7D4 on the rating of partner odor, the variant rs8109935 was genotyped in the whole sample. The rating of partner odor was significantly associated with scores of anxiety and depression. Depression (OR: 0.75, 95%CI: 0.56–0.98, p = 0.039) and anxiety (Robust Coef ± SE: −13 ± 0.6, p = 0.044) were inversely associated with pleasantness rating of partner odor. Ordered probit regression analysis shows that the rating of partner odor was significantly associated with the rs8109935 genotypes (Coef ± robust SE: 0.19 ± 0.09, p = 0.028). These findings suggest that odor perception between heterosexual partners may have an impact on the development of depression and anxiety, and that it might be influenced by genetic variation in OR7D4.
Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Burgueño, Adriana Laura. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina
Fil: Fernandez Gianotti, Tomas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina
Fil: Marillet, Guillermo.
Fil: Pirola, Carlos Jose. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Medicas; Argentina
description We performed a study on a sample of 856 individuals to answer whether the pleasantness/unpleasantness of the odor perception of their partners (rating of partner odor) is associated with depression and anxiety. To evaluate the influence of common genetic variation of the odorant receptor OR7D4 on the rating of partner odor, the variant rs8109935 was genotyped in the whole sample. The rating of partner odor was significantly associated with scores of anxiety and depression. Depression (OR: 0.75, 95%CI: 0.56–0.98, p = 0.039) and anxiety (Robust Coef ± SE: −13 ± 0.6, p = 0.044) were inversely associated with pleasantness rating of partner odor. Ordered probit regression analysis shows that the rating of partner odor was significantly associated with the rs8109935 genotypes (Coef ± robust SE: 0.19 ± 0.09, p = 0.028). These findings suggest that odor perception between heterosexual partners may have an impact on the development of depression and anxiety, and that it might be influenced by genetic variation in OR7D4.
publishDate 2011
dc.date.none.fl_str_mv 2011-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/14974
Sookoian, Silvia Cristina; Burgueño, Adriana Laura; Fernandez Gianotti, Tomas; Marillet, Guillermo; Pirola, Carlos Jose; Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4; Elsevier Science; Biological Psychology; 86; 3; 3-2011; 153-157
0301-0511
url http://hdl.handle.net/11336/14974
identifier_str_mv Sookoian, Silvia Cristina; Burgueño, Adriana Laura; Fernandez Gianotti, Tomas; Marillet, Guillermo; Pirola, Carlos Jose; Odor perception between heterosexual partners: Its association with depression, anxiety, and genetic variation in odorant receptor OR7D4; Elsevier Science; Biological Psychology; 86; 3; 3-2011; 153-157
0301-0511
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0301051110003005
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.biopsycho.2010.11.003
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.952241

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