Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity

Autores
Goyeneche, Rosario; Fanovich, Maria Alejandra; Rodríguez Rodrígues, Christian Fernando Ariel; Nicolao, María Celeste; Di Scala, Karina Cecilia
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Supercritical Fluid Extraction by using CO2 can be employed as an alternative to conventional methods for extracting functional compounds. Overall extractions curves for extractions of bioactive compounds from radish leaves were performed using scCO2 adding ethanol as co-solvent. Yield, total phenolic compounds, total flavonoids and antioxidant capacity were determined for each extract. The best results were obtained at 35 °C/400 bar and 40 °C/400 bar, with values of total phenolics 1375 mg GAE/100 g d.m. and 1455 mg GAE/100 g d.m., respectively. Antioxidant capacity by DPPH values were 359 mg TE/100 g d.m. (35 °C/400 bar) and 403 mg TE/100 g d.m. (40 °C/400 bar). Maturation of dendritic cells was not promoted being these extracts promising and interesting sources of antioxidative and anti-inflammatory agents for future uses in the pharmaceutical and alimentary industries.
Fil: Goyeneche, Rosario. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química. Grupo de Investigación en Ingeniería en Alimentos; Argentina
Fil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
Fil: Rodríguez Rodrígues, Christian Fernando Ariel. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Nicolao, María Celeste. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Di Scala, Karina Cecilia. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química. Grupo de Investigación en Ingeniería en Alimentos; Argentina
Materia
Bioactive Compounds
Integral Use
Supercritical Carbon Dioxide
Raphanus Sativus
Cytotoxicity
Dendritic Cell Maturation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/91851
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicityGoyeneche, RosarioFanovich, Maria AlejandraRodríguez Rodrígues, Christian Fernando ArielNicolao, María CelesteDi Scala, Karina CeciliaBioactive CompoundsIntegral UseSupercritical Carbon DioxideRaphanus SativusCytotoxicityDendritic Cell Maturationhttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2Supercritical Fluid Extraction by using CO2 can be employed as an alternative to conventional methods for extracting functional compounds. Overall extractions curves for extractions of bioactive compounds from radish leaves were performed using scCO2 adding ethanol as co-solvent. Yield, total phenolic compounds, total flavonoids and antioxidant capacity were determined for each extract. The best results were obtained at 35 °C/400 bar and 40 °C/400 bar, with values of total phenolics 1375 mg GAE/100 g d.m. and 1455 mg GAE/100 g d.m., respectively. Antioxidant capacity by DPPH values were 359 mg TE/100 g d.m. (35 °C/400 bar) and 403 mg TE/100 g d.m. (40 °C/400 bar). Maturation of dendritic cells was not promoted being these extracts promising and interesting sources of antioxidative and anti-inflammatory agents for future uses in the pharmaceutical and alimentary industries.Fil: Goyeneche, Rosario. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química. Grupo de Investigación en Ingeniería en Alimentos; ArgentinaFil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Rodríguez Rodrígues, Christian Fernando Ariel. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Nicolao, María Celeste. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Di Scala, Karina Cecilia. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química. Grupo de Investigación en Ingeniería en Alimentos; ArgentinaElsevier Science2018-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/91851Goyeneche, Rosario; Fanovich, Maria Alejandra; Rodríguez Rodrígues, Christian Fernando Ariel; Nicolao, María Celeste; Di Scala, Karina Cecilia; Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity; Elsevier Science; Journal of Supercritical Fluids; 135; 5-2018; 78-830896-8446CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://linkinghub.elsevier.com/retrieve/pii/S0896844617308276info:eu-repo/semantics/altIdentifier/doi/10.1016/j.supflu.2018.01.004info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T10:51:16Zoai:ri.conicet.gov.ar:11336/91851instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 10:51:17.063CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
title Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
spellingShingle Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
Goyeneche, Rosario
Bioactive Compounds
Integral Use
Supercritical Carbon Dioxide
Raphanus Sativus
Cytotoxicity
Dendritic Cell Maturation
title_short Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
title_full Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
title_fullStr Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
title_full_unstemmed Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
title_sort Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity
dc.creator.none.fl_str_mv Goyeneche, Rosario
Fanovich, Maria Alejandra
Rodríguez Rodrígues, Christian Fernando Ariel
Nicolao, María Celeste
Di Scala, Karina Cecilia
author Goyeneche, Rosario
author_facet Goyeneche, Rosario
Fanovich, Maria Alejandra
Rodríguez Rodrígues, Christian Fernando Ariel
Nicolao, María Celeste
Di Scala, Karina Cecilia
author_role author
author2 Fanovich, Maria Alejandra
Rodríguez Rodrígues, Christian Fernando Ariel
Nicolao, María Celeste
Di Scala, Karina Cecilia
author2_role author
author
author
author
dc.subject.none.fl_str_mv Bioactive Compounds
Integral Use
Supercritical Carbon Dioxide
Raphanus Sativus
Cytotoxicity
Dendritic Cell Maturation
topic Bioactive Compounds
Integral Use
Supercritical Carbon Dioxide
Raphanus Sativus
Cytotoxicity
Dendritic Cell Maturation
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Supercritical Fluid Extraction by using CO2 can be employed as an alternative to conventional methods for extracting functional compounds. Overall extractions curves for extractions of bioactive compounds from radish leaves were performed using scCO2 adding ethanol as co-solvent. Yield, total phenolic compounds, total flavonoids and antioxidant capacity were determined for each extract. The best results were obtained at 35 °C/400 bar and 40 °C/400 bar, with values of total phenolics 1375 mg GAE/100 g d.m. and 1455 mg GAE/100 g d.m., respectively. Antioxidant capacity by DPPH values were 359 mg TE/100 g d.m. (35 °C/400 bar) and 403 mg TE/100 g d.m. (40 °C/400 bar). Maturation of dendritic cells was not promoted being these extracts promising and interesting sources of antioxidative and anti-inflammatory agents for future uses in the pharmaceutical and alimentary industries.
Fil: Goyeneche, Rosario. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química. Grupo de Investigación en Ingeniería en Alimentos; Argentina
Fil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
Fil: Rodríguez Rodrígues, Christian Fernando Ariel. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Nicolao, María Celeste. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Di Scala, Karina Cecilia. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química. Grupo de Investigación en Ingeniería en Alimentos; Argentina
description Supercritical Fluid Extraction by using CO2 can be employed as an alternative to conventional methods for extracting functional compounds. Overall extractions curves for extractions of bioactive compounds from radish leaves were performed using scCO2 adding ethanol as co-solvent. Yield, total phenolic compounds, total flavonoids and antioxidant capacity were determined for each extract. The best results were obtained at 35 °C/400 bar and 40 °C/400 bar, with values of total phenolics 1375 mg GAE/100 g d.m. and 1455 mg GAE/100 g d.m., respectively. Antioxidant capacity by DPPH values were 359 mg TE/100 g d.m. (35 °C/400 bar) and 403 mg TE/100 g d.m. (40 °C/400 bar). Maturation of dendritic cells was not promoted being these extracts promising and interesting sources of antioxidative and anti-inflammatory agents for future uses in the pharmaceutical and alimentary industries.
publishDate 2018
dc.date.none.fl_str_mv 2018-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/91851
Goyeneche, Rosario; Fanovich, Maria Alejandra; Rodríguez Rodrígues, Christian Fernando Ariel; Nicolao, María Celeste; Di Scala, Karina Cecilia; Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity; Elsevier Science; Journal of Supercritical Fluids; 135; 5-2018; 78-83
0896-8446
CONICET Digital
CONICET
url http://hdl.handle.net/11336/91851
identifier_str_mv Goyeneche, Rosario; Fanovich, Maria Alejandra; Rodríguez Rodrígues, Christian Fernando Ariel; Nicolao, María Celeste; Di Scala, Karina Cecilia; Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity; Elsevier Science; Journal of Supercritical Fluids; 135; 5-2018; 78-83
0896-8446
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://linkinghub.elsevier.com/retrieve/pii/S0896844617308276
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.supflu.2018.01.004
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.000565

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