Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices

Autores
Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery.
Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina
Fil: Baglivo, Fabricio Hugo. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina
Fil: Martinez, Juan Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España
Fil: Laguna, Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España
Materia
Ecg
Digital Signal Processing
Dispersion
Pca
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/12179

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network_name_str CONICET Digital (CONICET)
spelling Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indicesArini, Pedro DavidBaglivo, Fabricio HugoMartinez, Juan PabloLaguna, PabloEcgDigital Signal ProcessingDispersionPcahttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery.Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería; ArgentinaFil: Baglivo, Fabricio Hugo. Universidad de Buenos Aires. Facultad de Ingeniería; ArgentinaFil: Martinez, Juan Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; EspañaFil: Laguna, Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; EspañaSpringer Heidelberg2014-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/12179Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo; Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices; Springer Heidelberg; Medical And Biological Engineering And Computing; 52; 4; 1-2014; 375-3910140-0118enginfo:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007/s11517-014-1136-zinfo:eu-repo/semantics/altIdentifier/doi/10.1007/s11517-014-1136-zinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:57:35Zoai:ri.conicet.gov.ar:11336/12179instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:35.943CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
title Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
spellingShingle Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
Arini, Pedro David
Ecg
Digital Signal Processing
Dispersion
Pca
title_short Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
title_full Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
title_fullStr Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
title_full_unstemmed Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
title_sort Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
dc.creator.none.fl_str_mv Arini, Pedro David
Baglivo, Fabricio Hugo
Martinez, Juan Pablo
Laguna, Pablo
author Arini, Pedro David
author_facet Arini, Pedro David
Baglivo, Fabricio Hugo
Martinez, Juan Pablo
Laguna, Pablo
author_role author
author2 Baglivo, Fabricio Hugo
Martinez, Juan Pablo
Laguna, Pablo
author2_role author
author
author
dc.subject.none.fl_str_mv Ecg
Digital Signal Processing
Dispersion
Pca
topic Ecg
Digital Signal Processing
Dispersion
Pca
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery.
Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina
Fil: Baglivo, Fabricio Hugo. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina
Fil: Martinez, Juan Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España
Fil: Laguna, Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España
description In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery.
publishDate 2014
dc.date.none.fl_str_mv 2014-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/12179
Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo; Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices; Springer Heidelberg; Medical And Biological Engineering And Computing; 52; 4; 1-2014; 375-391
0140-0118
url http://hdl.handle.net/11336/12179
identifier_str_mv Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo; Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices; Springer Heidelberg; Medical And Biological Engineering And Computing; 52; 4; 1-2014; 375-391
0140-0118
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007/s11517-014-1136-z
info:eu-repo/semantics/altIdentifier/doi/10.1007/s11517-014-1136-z
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer Heidelberg
publisher.none.fl_str_mv Springer Heidelberg
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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