Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices
- Autores
- Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery.
Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina
Fil: Baglivo, Fabricio Hugo. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina
Fil: Martinez, Juan Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España
Fil: Laguna, Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España - Materia
-
Ecg
Digital Signal Processing
Dispersion
Pca - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/12179
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Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indicesArini, Pedro DavidBaglivo, Fabricio HugoMartinez, Juan PabloLaguna, PabloEcgDigital Signal ProcessingDispersionPcahttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery.Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería; ArgentinaFil: Baglivo, Fabricio Hugo. Universidad de Buenos Aires. Facultad de Ingeniería; ArgentinaFil: Martinez, Juan Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; EspañaFil: Laguna, Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; EspañaSpringer Heidelberg2014-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/12179Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo; Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices; Springer Heidelberg; Medical And Biological Engineering And Computing; 52; 4; 1-2014; 375-3910140-0118enginfo:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007/s11517-014-1136-zinfo:eu-repo/semantics/altIdentifier/doi/10.1007/s11517-014-1136-zinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:57:35Zoai:ri.conicet.gov.ar:11336/12179instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:35.943CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
title |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
spellingShingle |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices Arini, Pedro David Ecg Digital Signal Processing Dispersion Pca |
title_short |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
title_full |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
title_fullStr |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
title_full_unstemmed |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
title_sort |
Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices |
dc.creator.none.fl_str_mv |
Arini, Pedro David Baglivo, Fabricio Hugo Martinez, Juan Pablo Laguna, Pablo |
author |
Arini, Pedro David |
author_facet |
Arini, Pedro David Baglivo, Fabricio Hugo Martinez, Juan Pablo Laguna, Pablo |
author_role |
author |
author2 |
Baglivo, Fabricio Hugo Martinez, Juan Pablo Laguna, Pablo |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
Ecg Digital Signal Processing Dispersion Pca |
topic |
Ecg Digital Signal Processing Dispersion Pca |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.11 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery. Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina Fil: Baglivo, Fabricio Hugo. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina Fil: Martinez, Juan Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España Fil: Laguna, Pablo. Universidad de Zaragoza; España. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine; España |
description |
In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices of VRD (S-VRD), based on the eigenvalues of the spatial correlation matrix of the ECG. The T-wave peak-to-end interval ITPE index showed statistically significant differences during left anterior descending artery and right coronary artery (RCA) occlusion for almost the complete time course of the PCI procedure with respect to the control recording. Regarding S-VRD indices, we observed statistically significant increases in the ratio of second to the first eigenvalue IT21, the ratio of the third to the first eigenvalue IT31 and the T-wave residuum ITWR during RCA occlusions. We also found a statistically significant increase in the IT31 during left circumflex artery occlusions. To evaluate the evolution of VRD indices during acute ischemia, we calculated the relative change parameter RI for each index I. Maximal relative changes (RI) during acute ischemia were found for the S-VRD indices IT21, the first eigenvalue Iλ1 and the second eigenvalue Iλ2, with changes 64, 57 and 52 times their baseline range of variation during the control recording, respectively. Also, we found that relative changes with respect to the baseline were higher in patients with T-wave alternans (TWA) than in those without TWA. In conclusion, results suggest that ITPE as well as IT21, IT31 and ITWR are very responsive to dispersion changes induced by ischemia, but with a behavior which very much depends on the occluded artery. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/12179 Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo; Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices; Springer Heidelberg; Medical And Biological Engineering And Computing; 52; 4; 1-2014; 375-391 0140-0118 |
url |
http://hdl.handle.net/11336/12179 |
identifier_str_mv |
Arini, Pedro David; Baglivo, Fabricio Hugo; Martinez, Juan Pablo; Laguna, Pablo; Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices; Springer Heidelberg; Medical And Biological Engineering And Computing; 52; 4; 1-2014; 375-391 0140-0118 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007/s11517-014-1136-z info:eu-repo/semantics/altIdentifier/doi/10.1007/s11517-014-1136-z |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Springer Heidelberg |
publisher.none.fl_str_mv |
Springer Heidelberg |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613722308345856 |
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13.070432 |