A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease

Autores
Bril, Andrea; Pérez Lloret, Santiago; Rossi, Malco Damián; Fariña, Sofía; Morisset, Pierre; Sorrentino, Laura; Iglesias, Micaela; Medina Escobar, Alex; Millar Vernetti, Patricio; Cerquetti, Daniel; Merello, Marcelo Jorge
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Weight loss is a multifactorial disorder commonly affecting Parkinson?s disease patients. The aim of this study was to investigate the relationship between body weight, nutritional status, physical activity, and Parkinson?s disease-related factors. A total of 114 consecutive Parkinson?s disease patients without dietary restrictions were evaluated prospectively with respect to: nutritional status (Mini Nutritional Assessment), physical activity level (Yale Physical Activity Survey), MDS-UPDRS score, olfactory function, depression, cognitive functionand impulse-control disorders, among other variables. Structural equation modeling was used to build multivariate models and to calculate standardized regression weights (srw) for pairs of variables, which are homologous to correlation coefficients, taking into account the effects of all other variables in the model. Sixty (53%) patients were males. Mean age was 66.1 ± 9.8 years and mean disease duration was 8.3 ± 5.6 years. Longer disease duration was negatively related to nutritional status (srw = −0.25; p = 0.01). UPDRS II + III score was associated with reduced cognitive function (srw = −0.39; p = 0.01), which was positivelyrelated to nutritional status (srw = 0.23; p = 0.01). Finally, nutritional status was positively related to body weight (srw = 0.22, p < 0.01). Binge eating and physical activity were also directly and positively related to body weight (srw = 0.32; p = 0.001 and srw = 0.23; p = 0.001). Nutritional status, binge eating and physical activity were directly and independently related to body weight in our sample of Parkinson?s disease patients. Therefore, physicians should actively explore nutritional status and binge eating in Parkinson?s disease patients to avoid alterations in body weight regulation. Effects of physical activity should be further explored.
Fil: Bril, Andrea. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Rossi, Malco Damián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Fariña, Sofía. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Morisset, Pierre. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Sorrentino, Laura. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Iglesias, Micaela. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Medina Escobar, Alex. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Millar Vernetti, Patricio. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Cerquetti, Daniel. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Merello, Marcelo Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Materia
Weight
Parkinson
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/77345
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s diseaseBril, AndreaPérez Lloret, SantiagoRossi, Malco DamiánFariña, SofíaMorisset, PierreSorrentino, LauraIglesias, MicaelaMedina Escobar, AlexMillar Vernetti, PatricioCerquetti, DanielMerello, Marcelo JorgeWeightParkinsonhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Weight loss is a multifactorial disorder commonly affecting Parkinson?s disease patients. The aim of this study was to investigate the relationship between body weight, nutritional status, physical activity, and Parkinson?s disease-related factors. A total of 114 consecutive Parkinson?s disease patients without dietary restrictions were evaluated prospectively with respect to: nutritional status (Mini Nutritional Assessment), physical activity level (Yale Physical Activity Survey), MDS-UPDRS score, olfactory function, depression, cognitive functionand impulse-control disorders, among other variables. Structural equation modeling was used to build multivariate models and to calculate standardized regression weights (srw) for pairs of variables, which are homologous to correlation coefficients, taking into account the effects of all other variables in the model. Sixty (53%) patients were males. Mean age was 66.1 ± 9.8 years and mean disease duration was 8.3 ± 5.6 years. Longer disease duration was negatively related to nutritional status (srw = −0.25; p = 0.01). UPDRS II + III score was associated with reduced cognitive function (srw = −0.39; p = 0.01), which was positivelyrelated to nutritional status (srw = 0.23; p = 0.01). Finally, nutritional status was positively related to body weight (srw = 0.22, p < 0.01). Binge eating and physical activity were also directly and positively related to body weight (srw = 0.32; p = 0.001 and srw = 0.23; p = 0.001). Nutritional status, binge eating and physical activity were directly and independently related to body weight in our sample of Parkinson?s disease patients. Therefore, physicians should actively explore nutritional status and binge eating in Parkinson?s disease patients to avoid alterations in body weight regulation. Effects of physical activity should be further explored.Fil: Bril, Andrea. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Rossi, Malco Damián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Fariña, Sofía. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Morisset, Pierre. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Sorrentino, Laura. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Iglesias, Micaela. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Medina Escobar, Alex. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Millar Vernetti, Patricio. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Cerquetti, Daniel. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Merello, Marcelo Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaNature Publishing Group2017-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/77345Bril, Andrea; Pérez Lloret, Santiago; Rossi, Malco Damián; Fariña, Sofía; Morisset, Pierre; et al.; A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease; Nature Publishing Group; npj Parkinson's Disease; 3; 1; 5-2017; 1-52373-8057CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41531-017-0018-0info:eu-repo/semantics/altIdentifier/doi/10.1038/s41531-017-0018-0info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:57:12Zoai:ri.conicet.gov.ar:11336/77345instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:12.464CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
title A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
spellingShingle A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
Bril, Andrea
Weight
Parkinson
title_short A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
title_full A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
title_fullStr A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
title_full_unstemmed A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
title_sort A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease
dc.creator.none.fl_str_mv Bril, Andrea
Pérez Lloret, Santiago
Rossi, Malco Damián
Fariña, Sofía
Morisset, Pierre
Sorrentino, Laura
Iglesias, Micaela
Medina Escobar, Alex
Millar Vernetti, Patricio
Cerquetti, Daniel
Merello, Marcelo Jorge
author Bril, Andrea
author_facet Bril, Andrea
Pérez Lloret, Santiago
Rossi, Malco Damián
Fariña, Sofía
Morisset, Pierre
Sorrentino, Laura
Iglesias, Micaela
Medina Escobar, Alex
Millar Vernetti, Patricio
Cerquetti, Daniel
Merello, Marcelo Jorge
author_role author
author2 Pérez Lloret, Santiago
Rossi, Malco Damián
Fariña, Sofía
Morisset, Pierre
Sorrentino, Laura
Iglesias, Micaela
Medina Escobar, Alex
Millar Vernetti, Patricio
Cerquetti, Daniel
Merello, Marcelo Jorge
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Weight
Parkinson
topic Weight
Parkinson
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Weight loss is a multifactorial disorder commonly affecting Parkinson?s disease patients. The aim of this study was to investigate the relationship between body weight, nutritional status, physical activity, and Parkinson?s disease-related factors. A total of 114 consecutive Parkinson?s disease patients without dietary restrictions were evaluated prospectively with respect to: nutritional status (Mini Nutritional Assessment), physical activity level (Yale Physical Activity Survey), MDS-UPDRS score, olfactory function, depression, cognitive functionand impulse-control disorders, among other variables. Structural equation modeling was used to build multivariate models and to calculate standardized regression weights (srw) for pairs of variables, which are homologous to correlation coefficients, taking into account the effects of all other variables in the model. Sixty (53%) patients were males. Mean age was 66.1 ± 9.8 years and mean disease duration was 8.3 ± 5.6 years. Longer disease duration was negatively related to nutritional status (srw = −0.25; p = 0.01). UPDRS II + III score was associated with reduced cognitive function (srw = −0.39; p = 0.01), which was positivelyrelated to nutritional status (srw = 0.23; p = 0.01). Finally, nutritional status was positively related to body weight (srw = 0.22, p < 0.01). Binge eating and physical activity were also directly and positively related to body weight (srw = 0.32; p = 0.001 and srw = 0.23; p = 0.001). Nutritional status, binge eating and physical activity were directly and independently related to body weight in our sample of Parkinson?s disease patients. Therefore, physicians should actively explore nutritional status and binge eating in Parkinson?s disease patients to avoid alterations in body weight regulation. Effects of physical activity should be further explored.
Fil: Bril, Andrea. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Rossi, Malco Damián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Fariña, Sofía. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Morisset, Pierre. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Sorrentino, Laura. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Iglesias, Micaela. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Medina Escobar, Alex. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Millar Vernetti, Patricio. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Cerquetti, Daniel. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Merello, Marcelo Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
description Weight loss is a multifactorial disorder commonly affecting Parkinson?s disease patients. The aim of this study was to investigate the relationship between body weight, nutritional status, physical activity, and Parkinson?s disease-related factors. A total of 114 consecutive Parkinson?s disease patients without dietary restrictions were evaluated prospectively with respect to: nutritional status (Mini Nutritional Assessment), physical activity level (Yale Physical Activity Survey), MDS-UPDRS score, olfactory function, depression, cognitive functionand impulse-control disorders, among other variables. Structural equation modeling was used to build multivariate models and to calculate standardized regression weights (srw) for pairs of variables, which are homologous to correlation coefficients, taking into account the effects of all other variables in the model. Sixty (53%) patients were males. Mean age was 66.1 ± 9.8 years and mean disease duration was 8.3 ± 5.6 years. Longer disease duration was negatively related to nutritional status (srw = −0.25; p = 0.01). UPDRS II + III score was associated with reduced cognitive function (srw = −0.39; p = 0.01), which was positivelyrelated to nutritional status (srw = 0.23; p = 0.01). Finally, nutritional status was positively related to body weight (srw = 0.22, p < 0.01). Binge eating and physical activity were also directly and positively related to body weight (srw = 0.32; p = 0.001 and srw = 0.23; p = 0.001). Nutritional status, binge eating and physical activity were directly and independently related to body weight in our sample of Parkinson?s disease patients. Therefore, physicians should actively explore nutritional status and binge eating in Parkinson?s disease patients to avoid alterations in body weight regulation. Effects of physical activity should be further explored.
publishDate 2017
dc.date.none.fl_str_mv 2017-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/77345
Bril, Andrea; Pérez Lloret, Santiago; Rossi, Malco Damián; Fariña, Sofía; Morisset, Pierre; et al.; A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease; Nature Publishing Group; npj Parkinson's Disease; 3; 1; 5-2017; 1-5
2373-8057
CONICET Digital
CONICET
url http://hdl.handle.net/11336/77345
identifier_str_mv Bril, Andrea; Pérez Lloret, Santiago; Rossi, Malco Damián; Fariña, Sofía; Morisset, Pierre; et al.; A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease; Nature Publishing Group; npj Parkinson's Disease; 3; 1; 5-2017; 1-5
2373-8057
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41531-017-0018-0
info:eu-repo/semantics/altIdentifier/doi/10.1038/s41531-017-0018-0
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.069144

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