Multiple myeloma in horses, dogs and cats: A comparative review focused on clinical signs and pathogenesis

• Autores: Muñoz, A.; Riber, C.; Satué, K.; Trigo, Pablo Ignacio; Gómez Díez, M.; Castejón, F.M.
• Año de publicación: 2013
• Idioma: inglés
• Tipo de recurso: parte de libro
• Materia: VETERINARY; TUMOR; ONCOLOGY; BLOOD
• Institución: Consejo Nacional de Investigaciones Científicas y Técnicas

Multiple myeloma (MM) or plasma cell myeloma is a neoplastic proliferation of plasma cells that primarily involves the bone marrow but may originate from extramedullary sites [1-4]. Although it is uncommon in veterinary medicine, it has been reported in several species, including cats, dogs and, horses. The frequency of MM in cats is slightly <1% of all malignant neoplasms. Canine MMs account for only 0.3% of all malignancies in dogs. MMs account approximately 2% of all hematopoietic neoplasms in both dogs and cats. Most of the reports in the literature are limited to 1 to 16 case studies. However, in a recent report regarding the incidence of bone disorders diagnosed in dogs, MM was the second most frequently diagnosed neoplastic condition in canine bone marrow.
Fil: Muñoz, A.. No especifíca;
Fil: Riber, C.. No especifíca;
Fil: Satué, K.. No especifíca;
Fil: Trigo, Pablo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
Fil: Gómez Díez, M.. No especifíca;
Fil: Castejón, F.M.. No especifíca;