Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation

Autores
Silvero, María Jazmín; Arguello, Gerardo Aníbal; Becerra, María Cecilia
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Gold nanoparticles synthesized through sodium citrate (A-AuNPs) and sodium borohydrade (B-AuNPs) reduction of Au3+ and a photochemically initiated method (C-AuNPs) were tested for possible application in Photodynamic Antibacterial Chemotherapy. None of them presented inhibitory activity against bacterial suspensions in dark conditions using the cylinders inhibition method; however, a total inhibition of Staphylococcus aureus ATCC 29213 and an extended-spectrum beta-lactamases-producing Escherichia coli ATCC 25922 growth were observed when incubated with 2 mM B-AuNPs and irradiated with LEDs at 525 nm for 12 h. Characterization of the interaction between S.aureus and B-AuNPs was demonstrated through an optimized procedure for TEM. These results probe that B-AuNPs have a good potential as photosensitizers for PACT.
Fil: Silvero, María Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Arguello, Gerardo Aníbal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Becerra, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Materia
Gold Nanoparticles
Staphylococcus Aureus
Escherichia Coli
Photodynamic Antibacterial Chemoterapy
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/22553
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's IrradiationSilvero, María JazmínArguello, Gerardo AníbalBecerra, María CeciliaGold NanoparticlesStaphylococcus AureusEscherichia ColiPhotodynamic Antibacterial Chemoterapyhttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2Gold nanoparticles synthesized through sodium citrate (A-AuNPs) and sodium borohydrade (B-AuNPs) reduction of Au3+ and a photochemically initiated method (C-AuNPs) were tested for possible application in Photodynamic Antibacterial Chemotherapy. None of them presented inhibitory activity against bacterial suspensions in dark conditions using the cylinders inhibition method; however, a total inhibition of Staphylococcus aureus ATCC 29213 and an extended-spectrum beta-lactamases-producing Escherichia coli ATCC 25922 growth were observed when incubated with 2 mM B-AuNPs and irradiated with LEDs at 525 nm for 12 h. Characterization of the interaction between S.aureus and B-AuNPs was demonstrated through an optimized procedure for TEM. These results probe that B-AuNPs have a good potential as photosensitizers for PACT.Fil: Silvero, María Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Arguello, Gerardo Aníbal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Becerra, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaAmerican Scientific Publishers2014-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/22553Silvero, María Jazmín; Arguello, Gerardo Aníbal; Becerra, María Cecilia; Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation; American Scientific Publishers; Journal of Nanopharmaceutics and Drug Delivery; 2; 2; 12-2014; 148-1522167-93122167-9320CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1166/jnd.2014.1048info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/contentone/asp/jnd/2014/00000002/00000002/art00006info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T10:42:02Zoai:ri.conicet.gov.ar:11336/22553instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 10:42:02.534CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
title Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
spellingShingle Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
Silvero, María Jazmín
Gold Nanoparticles
Staphylococcus Aureus
Escherichia Coli
Photodynamic Antibacterial Chemoterapy
title_short Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
title_full Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
title_fullStr Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
title_full_unstemmed Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
title_sort Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation
dc.creator.none.fl_str_mv Silvero, María Jazmín
Arguello, Gerardo Aníbal
Becerra, María Cecilia
author Silvero, María Jazmín
author_facet Silvero, María Jazmín
Arguello, Gerardo Aníbal
Becerra, María Cecilia
author_role author
author2 Arguello, Gerardo Aníbal
Becerra, María Cecilia
author2_role author
author
dc.subject.none.fl_str_mv Gold Nanoparticles
Staphylococcus Aureus
Escherichia Coli
Photodynamic Antibacterial Chemoterapy
topic Gold Nanoparticles
Staphylococcus Aureus
Escherichia Coli
Photodynamic Antibacterial Chemoterapy
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Gold nanoparticles synthesized through sodium citrate (A-AuNPs) and sodium borohydrade (B-AuNPs) reduction of Au3+ and a photochemically initiated method (C-AuNPs) were tested for possible application in Photodynamic Antibacterial Chemotherapy. None of them presented inhibitory activity against bacterial suspensions in dark conditions using the cylinders inhibition method; however, a total inhibition of Staphylococcus aureus ATCC 29213 and an extended-spectrum beta-lactamases-producing Escherichia coli ATCC 25922 growth were observed when incubated with 2 mM B-AuNPs and irradiated with LEDs at 525 nm for 12 h. Characterization of the interaction between S.aureus and B-AuNPs was demonstrated through an optimized procedure for TEM. These results probe that B-AuNPs have a good potential as photosensitizers for PACT.
Fil: Silvero, María Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Arguello, Gerardo Aníbal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Becerra, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
description Gold nanoparticles synthesized through sodium citrate (A-AuNPs) and sodium borohydrade (B-AuNPs) reduction of Au3+ and a photochemically initiated method (C-AuNPs) were tested for possible application in Photodynamic Antibacterial Chemotherapy. None of them presented inhibitory activity against bacterial suspensions in dark conditions using the cylinders inhibition method; however, a total inhibition of Staphylococcus aureus ATCC 29213 and an extended-spectrum beta-lactamases-producing Escherichia coli ATCC 25922 growth were observed when incubated with 2 mM B-AuNPs and irradiated with LEDs at 525 nm for 12 h. Characterization of the interaction between S.aureus and B-AuNPs was demonstrated through an optimized procedure for TEM. These results probe that B-AuNPs have a good potential as photosensitizers for PACT.
publishDate 2014
dc.date.none.fl_str_mv 2014-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/22553
Silvero, María Jazmín; Arguello, Gerardo Aníbal; Becerra, María Cecilia; Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation; American Scientific Publishers; Journal of Nanopharmaceutics and Drug Delivery; 2; 2; 12-2014; 148-152
2167-9312
2167-9320
CONICET Digital
CONICET
url http://hdl.handle.net/11336/22553
identifier_str_mv Silvero, María Jazmín; Arguello, Gerardo Aníbal; Becerra, María Cecilia; Photodynamic Antibacterial Chemotherapy (PACT) Against Staphylococcus aureus and Escherichia coli Using Gold Nanoparticles and LED's Irradiation; American Scientific Publishers; Journal of Nanopharmaceutics and Drug Delivery; 2; 2; 12-2014; 148-152
2167-9312
2167-9320
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/contentone/asp/jnd/2014/00000002/00000002/art00006
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Scientific Publishers
publisher.none.fl_str_mv American Scientific Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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