Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results

Autores
Gloriani, Alejandro H.; Arranz, Isabel; Matezanz, Beatriz; Issolio, Luis Alberto; Menéndez, José Antonio; Mar, Santiago; Galindo, Alicia; Aparicio, Juan Antonio
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
PURPOSE: To measure the sensitivity of small retinal areas by reducing the influence of the adaptation state of the rest of the retina. To assess the functional behaviour of the retina of several patients affected by different types of retinitis pigmentosa (RP). METHODS: A prospective study was performed. Five eyes of patients with retinal diseases and different genetic mutations were studied at the University of Valladolid: three typical RP, one cone rod dystrophy (CRD) and one Bardet-Biedl syndrome (BBS). One of the RP patients was analysed again 18 months after the first measurements. A two-maxwellian view optical arrangement was used to measure the luminance thresholds of retinal areas 1 deg sized under dark and low photopic adaptation conditions. Linear regression fits of these threshold contrasts as a function of the eccentricity were used to compare the sensitivity of the patients with respect to the control group.RESULTS: The slopes of the linear fits of the other typical RP patients were higher than those of the control group. The parameters of the linear fits of the RP patient measured twice changed significantly with time. CONCLUSIONS: The designed psychophysical method provides, in all cases, coherent results with the expected ones according to the genetic mutation of the patients. The technique seems to be very sensitive to changes in the retinal response. It can be easily incorporated as a technical complement to the traditional perimetry.
Fil: Gloriani, Alejandro H.. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Arranz, Isabel. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Matezanz, Beatriz. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Issolio, Luis Alberto. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Laboratorio de Luminotecnia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; Argentina
Fil: Menéndez, José Antonio. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Mar, Santiago. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Galindo, Alicia. Hospital Universitario Río Ortega. Valladolid; España
Fil: Aparicio, Juan Antonio. Universidad de Valladolid. Facultad de Ciencias; España
Materia
RETINITIS PIGMENTOSA
CONE-ROD DISTROPHY
PHOTORECEPTORS
PSYCHOPHYSICS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/63104
Acceder
id CONICETDig_2c4482d6c8a74e4d28ac0d94536857c1
oai_identifier_str oai:ri.conicet.gov.ar:11336/63104
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Small-field perimetry applied to different types of retinitis pigmentosa: preliminary resultsGloriani, Alejandro H.Arranz, IsabelMatezanz, BeatrizIssolio, Luis AlbertoMenéndez, José AntonioMar, SantiagoGalindo, AliciaAparicio, Juan AntonioRETINITIS PIGMENTOSACONE-ROD DISTROPHYPHOTORECEPTORSPSYCHOPHYSICShttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3PURPOSE: To measure the sensitivity of small retinal areas by reducing the influence of the adaptation state of the rest of the retina. To assess the functional behaviour of the retina of several patients affected by different types of retinitis pigmentosa (RP). METHODS: A prospective study was performed. Five eyes of patients with retinal diseases and different genetic mutations were studied at the University of Valladolid: three typical RP, one cone rod dystrophy (CRD) and one Bardet-Biedl syndrome (BBS). One of the RP patients was analysed again 18 months after the first measurements. A two-maxwellian view optical arrangement was used to measure the luminance thresholds of retinal areas 1 deg sized under dark and low photopic adaptation conditions. Linear regression fits of these threshold contrasts as a function of the eccentricity were used to compare the sensitivity of the patients with respect to the control group.RESULTS: The slopes of the linear fits of the other typical RP patients were higher than those of the control group. The parameters of the linear fits of the RP patient measured twice changed significantly with time. CONCLUSIONS: The designed psychophysical method provides, in all cases, coherent results with the expected ones according to the genetic mutation of the patients. The technique seems to be very sensitive to changes in the retinal response. It can be easily incorporated as a technical complement to the traditional perimetry.Fil: Gloriani, Alejandro H.. Universidad de Valladolid. Facultad de Ciencias; EspañaFil: Arranz, Isabel. Universidad de Valladolid. Facultad de Ciencias; EspañaFil: Matezanz, Beatriz. Universidad de Valladolid. Facultad de Ciencias; EspañaFil: Issolio, Luis Alberto. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Laboratorio de Luminotecnia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; ArgentinaFil: Menéndez, José Antonio. Universidad de Valladolid. Facultad de Ciencias; EspañaFil: Mar, Santiago. Universidad de Valladolid. Facultad de Ciencias; EspañaFil: Galindo, Alicia. Hospital Universitario Río Ortega. Valladolid; EspañaFil: Aparicio, Juan Antonio. Universidad de Valladolid. Facultad de Ciencias; EspañaOpen Access Text2017-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/63104Gloriani, Alejandro H.; Arranz, Isabel; Matezanz, Beatriz; Issolio, Luis Alberto; Menéndez, José Antonio; et al.; Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results; Open Access Text; New Frontiers in Ophthalmology; 3; 1; 2-2017; 1-52397-2092CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.15761/NFO.1000152info:eu-repo/semantics/altIdentifier/url/https://www.oatext.com/field-perimetry-applied-to-different-types-of-retinitis-pigmentosa-preliminary-results.phpinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:15:16Zoai:ri.conicet.gov.ar:11336/63104instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:15:17.111CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
title Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
spellingShingle Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
Gloriani, Alejandro H.
RETINITIS PIGMENTOSA
CONE-ROD DISTROPHY
PHOTORECEPTORS
PSYCHOPHYSICS
title_short Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
title_full Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
title_fullStr Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
title_full_unstemmed Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
title_sort Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
dc.creator.none.fl_str_mv Gloriani, Alejandro H.
Arranz, Isabel
Matezanz, Beatriz
Issolio, Luis Alberto
Menéndez, José Antonio
Mar, Santiago
Galindo, Alicia
Aparicio, Juan Antonio
author Gloriani, Alejandro H.
author_facet Gloriani, Alejandro H.
Arranz, Isabel
Matezanz, Beatriz
Issolio, Luis Alberto
Menéndez, José Antonio
Mar, Santiago
Galindo, Alicia
Aparicio, Juan Antonio
author_role author
author2 Arranz, Isabel
Matezanz, Beatriz
Issolio, Luis Alberto
Menéndez, José Antonio
Mar, Santiago
Galindo, Alicia
Aparicio, Juan Antonio
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv RETINITIS PIGMENTOSA
CONE-ROD DISTROPHY
PHOTORECEPTORS
PSYCHOPHYSICS
topic RETINITIS PIGMENTOSA
CONE-ROD DISTROPHY
PHOTORECEPTORS
PSYCHOPHYSICS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv PURPOSE: To measure the sensitivity of small retinal areas by reducing the influence of the adaptation state of the rest of the retina. To assess the functional behaviour of the retina of several patients affected by different types of retinitis pigmentosa (RP). METHODS: A prospective study was performed. Five eyes of patients with retinal diseases and different genetic mutations were studied at the University of Valladolid: three typical RP, one cone rod dystrophy (CRD) and one Bardet-Biedl syndrome (BBS). One of the RP patients was analysed again 18 months after the first measurements. A two-maxwellian view optical arrangement was used to measure the luminance thresholds of retinal areas 1 deg sized under dark and low photopic adaptation conditions. Linear regression fits of these threshold contrasts as a function of the eccentricity were used to compare the sensitivity of the patients with respect to the control group.RESULTS: The slopes of the linear fits of the other typical RP patients were higher than those of the control group. The parameters of the linear fits of the RP patient measured twice changed significantly with time. CONCLUSIONS: The designed psychophysical method provides, in all cases, coherent results with the expected ones according to the genetic mutation of the patients. The technique seems to be very sensitive to changes in the retinal response. It can be easily incorporated as a technical complement to the traditional perimetry.
Fil: Gloriani, Alejandro H.. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Arranz, Isabel. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Matezanz, Beatriz. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Issolio, Luis Alberto. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Laboratorio de Luminotecnia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; Argentina
Fil: Menéndez, José Antonio. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Mar, Santiago. Universidad de Valladolid. Facultad de Ciencias; España
Fil: Galindo, Alicia. Hospital Universitario Río Ortega. Valladolid; España
Fil: Aparicio, Juan Antonio. Universidad de Valladolid. Facultad de Ciencias; España
description PURPOSE: To measure the sensitivity of small retinal areas by reducing the influence of the adaptation state of the rest of the retina. To assess the functional behaviour of the retina of several patients affected by different types of retinitis pigmentosa (RP). METHODS: A prospective study was performed. Five eyes of patients with retinal diseases and different genetic mutations were studied at the University of Valladolid: three typical RP, one cone rod dystrophy (CRD) and one Bardet-Biedl syndrome (BBS). One of the RP patients was analysed again 18 months after the first measurements. A two-maxwellian view optical arrangement was used to measure the luminance thresholds of retinal areas 1 deg sized under dark and low photopic adaptation conditions. Linear regression fits of these threshold contrasts as a function of the eccentricity were used to compare the sensitivity of the patients with respect to the control group.RESULTS: The slopes of the linear fits of the other typical RP patients were higher than those of the control group. The parameters of the linear fits of the RP patient measured twice changed significantly with time. CONCLUSIONS: The designed psychophysical method provides, in all cases, coherent results with the expected ones according to the genetic mutation of the patients. The technique seems to be very sensitive to changes in the retinal response. It can be easily incorporated as a technical complement to the traditional perimetry.
publishDate 2017
dc.date.none.fl_str_mv 2017-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/63104
Gloriani, Alejandro H.; Arranz, Isabel; Matezanz, Beatriz; Issolio, Luis Alberto; Menéndez, José Antonio; et al.; Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results; Open Access Text; New Frontiers in Ophthalmology; 3; 1; 2-2017; 1-5
2397-2092
CONICET Digital
CONICET
url http://hdl.handle.net/11336/63104
identifier_str_mv Gloriani, Alejandro H.; Arranz, Isabel; Matezanz, Beatriz; Issolio, Luis Alberto; Menéndez, José Antonio; et al.; Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results; Open Access Text; New Frontiers in Ophthalmology; 3; 1; 2-2017; 1-5
2397-2092
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.15761/NFO.1000152
info:eu-repo/semantics/altIdentifier/url/https://www.oatext.com/field-perimetry-applied-to-different-types-of-retinitis-pigmentosa-preliminary-results.php
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Open Access Text
publisher.none.fl_str_mv Open Access Text
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083300588781568
score 13.22299

Publicaciones similares