Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions

Autores
Sathicq, Angel Gabriel; Ruiz, Diego Manuel; Constantieux, Tierry; Rodriguez, Jean; Romanelli, Gustavo Pablo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A series of trifluoromethylated hexahydropyrimidines was synthesized using Preyssler heteropoly acid H14NaP5W29MoO110 encapsulated in a silica framework as the catalyst under solvent-free conditions. This synthesis requires short reaction times (1.5 h) and 80 °C under solvent-free conditions to obtain good to excellent yields of 18 hexahydropyrimidine derivatives. Preyssler catalyst embedded in the silica matrix, unlike the bulk or supported on silica, is insoluble in polar media such as acetone, ethanol, or methanol, which allows easy removal of the reaction products without affecting catalytic activity.
Fil: Sathicq, Angel Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Fil: Ruiz, Diego Manuel. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Fil: Constantieux, Tierry. Aix-Marseille Université Centre Saint Jérôme; Institut des Sciences Moléculaires de Marseille-UMR CNRS; Francia
Fil: Rodriguez, Jean. Aix-Marseille Université Centre Saint Jérôme; Institut des Sciences Moléculaires de Marseille-UMR CNRS; Francia
Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Materia
Fluorinated Hexahydropyrimidines
Trifluoromethyl Derivatives
Preyssler Heteropolyacid Acid
Multicomponent Reactions
Encapsulated in A Silica Framework
Solvent-Free
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/8303
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/8303
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditionsSathicq, Angel GabrielRuiz, Diego ManuelConstantieux, TierryRodriguez, JeanRomanelli, Gustavo PabloFluorinated HexahydropyrimidinesTrifluoromethyl DerivativesPreyssler Heteropolyacid AcidMulticomponent ReactionsEncapsulated in A Silica FrameworkSolvent-Freehttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2https://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A series of trifluoromethylated hexahydropyrimidines was synthesized using Preyssler heteropoly acid H14NaP5W29MoO110 encapsulated in a silica framework as the catalyst under solvent-free conditions. This synthesis requires short reaction times (1.5 h) and 80 °C under solvent-free conditions to obtain good to excellent yields of 18 hexahydropyrimidine derivatives. Preyssler catalyst embedded in the silica matrix, unlike the bulk or supported on silica, is insoluble in polar media such as acetone, ethanol, or methanol, which allows easy removal of the reaction products without affecting catalytic activity.Fil: Sathicq, Angel Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; ArgentinaFil: Ruiz, Diego Manuel. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; ArgentinaFil: Constantieux, Tierry. Aix-Marseille Université Centre Saint Jérôme; Institut des Sciences Moléculaires de Marseille-UMR CNRS; FranciaFil: Rodriguez, Jean. Aix-Marseille Université Centre Saint Jérôme; Institut des Sciences Moléculaires de Marseille-UMR CNRS; FranciaFil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; ArgentinaThieme Medical Publ Inc2014-03-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8303Sathicq, Angel Gabriel; Ruiz, Diego Manuel; Constantieux, Tierry; Rodriguez, Jean; Romanelli, Gustavo Pablo; Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions; Thieme Medical Publ Inc; Synlett; 25; 6; 6-3-2014; 881-8830936-52141437-2096enginfo:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1340845info:eu-repo/semantics/altIdentifier/doi/10.1055/s-0033-1340845info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:20:39Zoai:ri.conicet.gov.ar:11336/8303instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:20:39.949CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
title Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
spellingShingle Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
Sathicq, Angel Gabriel
Fluorinated Hexahydropyrimidines
Trifluoromethyl Derivatives
Preyssler Heteropolyacid Acid
Multicomponent Reactions
Encapsulated in A Silica Framework
Solvent-Free
title_short Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
title_full Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
title_fullStr Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
title_full_unstemmed Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
title_sort Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions
dc.creator.none.fl_str_mv Sathicq, Angel Gabriel
Ruiz, Diego Manuel
Constantieux, Tierry
Rodriguez, Jean
Romanelli, Gustavo Pablo
author Sathicq, Angel Gabriel
author_facet Sathicq, Angel Gabriel
Ruiz, Diego Manuel
Constantieux, Tierry
Rodriguez, Jean
Romanelli, Gustavo Pablo
author_role author
author2 Ruiz, Diego Manuel
Constantieux, Tierry
Rodriguez, Jean
Romanelli, Gustavo Pablo
author2_role author
author
author
author
dc.subject.none.fl_str_mv Fluorinated Hexahydropyrimidines
Trifluoromethyl Derivatives
Preyssler Heteropolyacid Acid
Multicomponent Reactions
Encapsulated in A Silica Framework
Solvent-Free
topic Fluorinated Hexahydropyrimidines
Trifluoromethyl Derivatives
Preyssler Heteropolyacid Acid
Multicomponent Reactions
Encapsulated in A Silica Framework
Solvent-Free
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A series of trifluoromethylated hexahydropyrimidines was synthesized using Preyssler heteropoly acid H14NaP5W29MoO110 encapsulated in a silica framework as the catalyst under solvent-free conditions. This synthesis requires short reaction times (1.5 h) and 80 °C under solvent-free conditions to obtain good to excellent yields of 18 hexahydropyrimidine derivatives. Preyssler catalyst embedded in the silica matrix, unlike the bulk or supported on silica, is insoluble in polar media such as acetone, ethanol, or methanol, which allows easy removal of the reaction products without affecting catalytic activity.
Fil: Sathicq, Angel Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Fil: Ruiz, Diego Manuel. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Fil: Constantieux, Tierry. Aix-Marseille Université Centre Saint Jérôme; Institut des Sciences Moléculaires de Marseille-UMR CNRS; Francia
Fil: Rodriguez, Jean. Aix-Marseille Université Centre Saint Jérôme; Institut des Sciences Moléculaires de Marseille-UMR CNRS; Francia
Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
description A series of trifluoromethylated hexahydropyrimidines was synthesized using Preyssler heteropoly acid H14NaP5W29MoO110 encapsulated in a silica framework as the catalyst under solvent-free conditions. This synthesis requires short reaction times (1.5 h) and 80 °C under solvent-free conditions to obtain good to excellent yields of 18 hexahydropyrimidine derivatives. Preyssler catalyst embedded in the silica matrix, unlike the bulk or supported on silica, is insoluble in polar media such as acetone, ethanol, or methanol, which allows easy removal of the reaction products without affecting catalytic activity.
publishDate 2014
dc.date.none.fl_str_mv 2014-03-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8303
Sathicq, Angel Gabriel; Ruiz, Diego Manuel; Constantieux, Tierry; Rodriguez, Jean; Romanelli, Gustavo Pablo; Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions; Thieme Medical Publ Inc; Synlett; 25; 6; 6-3-2014; 881-883
0936-5214
1437-2096
url http://hdl.handle.net/11336/8303
identifier_str_mv Sathicq, Angel Gabriel; Ruiz, Diego Manuel; Constantieux, Tierry; Rodriguez, Jean; Romanelli, Gustavo Pablo; Preyssler heteropolyacids encapsulated in a silica framework for an efficient preparation of fluorinated hexahydropyrimidine derivatives in solvent-free conditions; Thieme Medical Publ Inc; Synlett; 25; 6; 6-3-2014; 881-883
0936-5214
1437-2096
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1340845
info:eu-repo/semantics/altIdentifier/doi/10.1055/s-0033-1340845
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Thieme Medical Publ Inc
publisher.none.fl_str_mv Thieme Medical Publ Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082585346703360
score 13.22299

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