New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions

Autores
Palermo, Valeria; Sathicq, Ángel Gabriel; Constantieux, Thierry; Rodriguez, Jean; Vázquez, Patricia Graciela; Romanelli, Gustavo Pablo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Solid acid catalysts based on the direct incorporation of the vanadium Keggin heteropolyacid (PMo11V) structure during the synthesis of silica by the sol–gel technique, in acidic media using tetraethyl orthosilicate (PMo11VSiO21, PMo11VSiO22, PMo11VSiO23, and PMo11VSiO24), were prepared and characterized by 31P-NMR, FT-IR, XRD, and textural properties (SBET). The acidic characteristics of the catalysts were determined by potentiometric titration with n-butylamine. A series of highly substituted hexahydropyrimidines were synthesized using these new materials, encapsulated in a silica framework, as catalyst in solvent-free conditions. This methodology requires short reaction time (1.5 h), a temperature of 80 °C in solvent free-conditions to obtain good to excellent yields of trifluoromethyl-hexahydropyrimidine derivatives. The Keggin catalyst embedded in the silica matrix is insoluble in polar media, which allows easy removal of the reaction products without affecting their catalytic activity.
Centro de Investigación y Desarrollo en Ciencias Aplicadas
Materia
Ciencias Exactas
Química
Keggin heteropolyacids
Silica sol–gel
HPA included in silica matrix
Trifluoromethylhexahydropyrimidines
Multicomponent reaction
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/138838

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oai_identifier_str oai:sedici.unlp.edu.ar:10915/138838
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable ConditionsPalermo, ValeriaSathicq, Ángel GabrielConstantieux, ThierryRodriguez, JeanVázquez, Patricia GracielaRomanelli, Gustavo PabloCiencias ExactasQuímicaKeggin heteropolyacidsSilica sol–gelHPA included in silica matrixTrifluoromethylhexahydropyrimidinesMulticomponent reactionSolid acid catalysts based on the direct incorporation of the vanadium Keggin heteropolyacid (PMo11V) structure during the synthesis of silica by the sol–gel technique, in acidic media using tetraethyl orthosilicate (PMo11VSiO21, PMo11VSiO22, PMo11VSiO23, and PMo11VSiO24), were prepared and characterized by 31P-NMR, FT-IR, XRD, and textural properties (SBET). The acidic characteristics of the catalysts were determined by potentiometric titration with n-butylamine. A series of highly substituted hexahydropyrimidines were synthesized using these new materials, encapsulated in a silica framework, as catalyst in solvent-free conditions. This methodology requires short reaction time (1.5 h), a temperature of 80 °C in solvent free-conditions to obtain good to excellent yields of trifluoromethyl-hexahydropyrimidine derivatives. The Keggin catalyst embedded in the silica matrix is insoluble in polar media, which allows easy removal of the reaction products without affecting their catalytic activity.Centro de Investigación y Desarrollo en Ciencias Aplicadas2015-02-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf1022-1032http://sedici.unlp.edu.ar/handle/10915/138838enginfo:eu-repo/semantics/altIdentifier/issn/1011-372xinfo:eu-repo/semantics/altIdentifier/issn/1572-879xinfo:eu-repo/semantics/altIdentifier/doi/10.1007/s10562-015-1498-3info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:31:52Zoai:sedici.unlp.edu.ar:10915/138838Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:31:52.295SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
title New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
spellingShingle New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
Palermo, Valeria
Ciencias Exactas
Química
Keggin heteropolyacids
Silica sol–gel
HPA included in silica matrix
Trifluoromethylhexahydropyrimidines
Multicomponent reaction
title_short New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
title_full New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
title_fullStr New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
title_full_unstemmed New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
title_sort New Vanadium Keggin Heteropolyacids Encapsulated in a Silica Framework : Recyclable Catalysts for the Synthesis of Highly Substituted Hexahydropyrimidines Under Suitable Conditions
dc.creator.none.fl_str_mv Palermo, Valeria
Sathicq, Ángel Gabriel
Constantieux, Thierry
Rodriguez, Jean
Vázquez, Patricia Graciela
Romanelli, Gustavo Pablo
author Palermo, Valeria
author_facet Palermo, Valeria
Sathicq, Ángel Gabriel
Constantieux, Thierry
Rodriguez, Jean
Vázquez, Patricia Graciela
Romanelli, Gustavo Pablo
author_role author
author2 Sathicq, Ángel Gabriel
Constantieux, Thierry
Rodriguez, Jean
Vázquez, Patricia Graciela
Romanelli, Gustavo Pablo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Química
Keggin heteropolyacids
Silica sol–gel
HPA included in silica matrix
Trifluoromethylhexahydropyrimidines
Multicomponent reaction
topic Ciencias Exactas
Química
Keggin heteropolyacids
Silica sol–gel
HPA included in silica matrix
Trifluoromethylhexahydropyrimidines
Multicomponent reaction
dc.description.none.fl_txt_mv Solid acid catalysts based on the direct incorporation of the vanadium Keggin heteropolyacid (PMo11V) structure during the synthesis of silica by the sol–gel technique, in acidic media using tetraethyl orthosilicate (PMo11VSiO21, PMo11VSiO22, PMo11VSiO23, and PMo11VSiO24), were prepared and characterized by 31P-NMR, FT-IR, XRD, and textural properties (SBET). The acidic characteristics of the catalysts were determined by potentiometric titration with n-butylamine. A series of highly substituted hexahydropyrimidines were synthesized using these new materials, encapsulated in a silica framework, as catalyst in solvent-free conditions. This methodology requires short reaction time (1.5 h), a temperature of 80 °C in solvent free-conditions to obtain good to excellent yields of trifluoromethyl-hexahydropyrimidine derivatives. The Keggin catalyst embedded in the silica matrix is insoluble in polar media, which allows easy removal of the reaction products without affecting their catalytic activity.
Centro de Investigación y Desarrollo en Ciencias Aplicadas
description Solid acid catalysts based on the direct incorporation of the vanadium Keggin heteropolyacid (PMo11V) structure during the synthesis of silica by the sol–gel technique, in acidic media using tetraethyl orthosilicate (PMo11VSiO21, PMo11VSiO22, PMo11VSiO23, and PMo11VSiO24), were prepared and characterized by 31P-NMR, FT-IR, XRD, and textural properties (SBET). The acidic characteristics of the catalysts were determined by potentiometric titration with n-butylamine. A series of highly substituted hexahydropyrimidines were synthesized using these new materials, encapsulated in a silica framework, as catalyst in solvent-free conditions. This methodology requires short reaction time (1.5 h), a temperature of 80 °C in solvent free-conditions to obtain good to excellent yields of trifluoromethyl-hexahydropyrimidine derivatives. The Keggin catalyst embedded in the silica matrix is insoluble in polar media, which allows easy removal of the reaction products without affecting their catalytic activity.
publishDate 2015
dc.date.none.fl_str_mv 2015-02-19
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/138838
url http://sedici.unlp.edu.ar/handle/10915/138838
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1011-372x
info:eu-repo/semantics/altIdentifier/issn/1572-879x
info:eu-repo/semantics/altIdentifier/doi/10.1007/s10562-015-1498-3
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
1022-1032
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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