Changes in immune response during pig gestation with a focus on cytokines

Autores
Velez, Carolina; Williamson, Delia Maria; Canovas, Mariela Lorena; Giai, Laura Romina; Rutland, Catrin; Pérez, William; Barbeito, Claudio Gustavo
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Pigs have the highest percentage of embryonic death not associated with specific diseases of all livestock species, at 20–45%. During gestation processes, a series of complex alterations can arise, including embryonic migration and elongation, maternal immunological recognition of pregnancy, and embryonic competition for implantation sites and subsequent nutrition requirements and development. Immune cells and cytokines act as mediators between other molecules in highly complex interactions between various cell types. However, other non-immune cells, such as trophoblast cells, are important in immune pregnancy regulation. Numerous studies have shed light on the crucial roles of several cytokines that regulate the inflammatory processes that characterize the interface between the fetus and the mother throughout normal porcine gestation, but most of these reports are limited to the implantational and peri-implantational periods. Increase in some proinflammatory cytokines have been found in other gestational periods, such as placental remodeling. Porcine immune changes during delivery have not been studied as deeply as in other species. This review details some of the immune system cells actively involved in the fetomaternal interface during porcine gestation, as well as the principal cells, cytokines, and molecules, such as antibodies, that play crucial roles in sow pregnancy, both in early and mid-to-late gestation.
Fil: Velez, Carolina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Williamson, Delia Maria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina
Fil: Canovas, Mariela Lorena. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina
Fil: Giai, Laura Romina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina
Fil: Rutland, Catrin. University of Nottingham; Estados Unidos
Fil: Pérez, William. Universidad de Montevideo; Uruguay
Fil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Materia
ASYMMETRIC ANTIBODIES
CYTOKINES
EMBRYO DEATH
EPITHELIOCHORIAL PLACENTA
INNATE IMMUNITY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/230937
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/230937
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Changes in immune response during pig gestation with a focus on cytokinesVelez, CarolinaWilliamson, Delia MariaCanovas, Mariela LorenaGiai, Laura RominaRutland, CatrinPérez, WilliamBarbeito, Claudio GustavoASYMMETRIC ANTIBODIESCYTOKINESEMBRYO DEATHEPITHELIOCHORIAL PLACENTAINNATE IMMUNITYhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Pigs have the highest percentage of embryonic death not associated with specific diseases of all livestock species, at 20–45%. During gestation processes, a series of complex alterations can arise, including embryonic migration and elongation, maternal immunological recognition of pregnancy, and embryonic competition for implantation sites and subsequent nutrition requirements and development. Immune cells and cytokines act as mediators between other molecules in highly complex interactions between various cell types. However, other non-immune cells, such as trophoblast cells, are important in immune pregnancy regulation. Numerous studies have shed light on the crucial roles of several cytokines that regulate the inflammatory processes that characterize the interface between the fetus and the mother throughout normal porcine gestation, but most of these reports are limited to the implantational and peri-implantational periods. Increase in some proinflammatory cytokines have been found in other gestational periods, such as placental remodeling. Porcine immune changes during delivery have not been studied as deeply as in other species. This review details some of the immune system cells actively involved in the fetomaternal interface during porcine gestation, as well as the principal cells, cytokines, and molecules, such as antibodies, that play crucial roles in sow pregnancy, both in early and mid-to-late gestation.Fil: Velez, Carolina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Williamson, Delia Maria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; ArgentinaFil: Canovas, Mariela Lorena. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; ArgentinaFil: Giai, Laura Romina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; ArgentinaFil: Rutland, Catrin. University of Nottingham; Estados UnidosFil: Pérez, William. Universidad de Montevideo; UruguayFil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaMultidisciplinary Digital Publishing Institute2024-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/230937Velez, Carolina; Williamson, Delia Maria; Canovas, Mariela Lorena; Giai, Laura Romina; Rutland, Catrin; et al.; Changes in immune response during pig gestation with a focus on cytokines; Multidisciplinary Digital Publishing Institute; Veterinary Sciences; 11; 1; 1-2024; 1-242306-7381CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/vetsci11010050info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2306-7381/11/1/50info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:43:05Zoai:ri.conicet.gov.ar:11336/230937instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:43:05.717CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Changes in immune response during pig gestation with a focus on cytokines
title Changes in immune response during pig gestation with a focus on cytokines
spellingShingle Changes in immune response during pig gestation with a focus on cytokines
Velez, Carolina
ASYMMETRIC ANTIBODIES
CYTOKINES
EMBRYO DEATH
EPITHELIOCHORIAL PLACENTA
INNATE IMMUNITY
title_short Changes in immune response during pig gestation with a focus on cytokines
title_full Changes in immune response during pig gestation with a focus on cytokines
title_fullStr Changes in immune response during pig gestation with a focus on cytokines
title_full_unstemmed Changes in immune response during pig gestation with a focus on cytokines
title_sort Changes in immune response during pig gestation with a focus on cytokines
dc.creator.none.fl_str_mv Velez, Carolina
Williamson, Delia Maria
Canovas, Mariela Lorena
Giai, Laura Romina
Rutland, Catrin
Pérez, William
Barbeito, Claudio Gustavo
author Velez, Carolina
author_facet Velez, Carolina
Williamson, Delia Maria
Canovas, Mariela Lorena
Giai, Laura Romina
Rutland, Catrin
Pérez, William
Barbeito, Claudio Gustavo
author_role author
author2 Williamson, Delia Maria
Canovas, Mariela Lorena
Giai, Laura Romina
Rutland, Catrin
Pérez, William
Barbeito, Claudio Gustavo
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ASYMMETRIC ANTIBODIES
CYTOKINES
EMBRYO DEATH
EPITHELIOCHORIAL PLACENTA
INNATE IMMUNITY
topic ASYMMETRIC ANTIBODIES
CYTOKINES
EMBRYO DEATH
EPITHELIOCHORIAL PLACENTA
INNATE IMMUNITY
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Pigs have the highest percentage of embryonic death not associated with specific diseases of all livestock species, at 20–45%. During gestation processes, a series of complex alterations can arise, including embryonic migration and elongation, maternal immunological recognition of pregnancy, and embryonic competition for implantation sites and subsequent nutrition requirements and development. Immune cells and cytokines act as mediators between other molecules in highly complex interactions between various cell types. However, other non-immune cells, such as trophoblast cells, are important in immune pregnancy regulation. Numerous studies have shed light on the crucial roles of several cytokines that regulate the inflammatory processes that characterize the interface between the fetus and the mother throughout normal porcine gestation, but most of these reports are limited to the implantational and peri-implantational periods. Increase in some proinflammatory cytokines have been found in other gestational periods, such as placental remodeling. Porcine immune changes during delivery have not been studied as deeply as in other species. This review details some of the immune system cells actively involved in the fetomaternal interface during porcine gestation, as well as the principal cells, cytokines, and molecules, such as antibodies, that play crucial roles in sow pregnancy, both in early and mid-to-late gestation.
Fil: Velez, Carolina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Williamson, Delia Maria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina
Fil: Canovas, Mariela Lorena. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina
Fil: Giai, Laura Romina. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento Ciencias Básicas. Cátedra de Biología General; Argentina
Fil: Rutland, Catrin. University of Nottingham; Estados Unidos
Fil: Pérez, William. Universidad de Montevideo; Uruguay
Fil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
description Pigs have the highest percentage of embryonic death not associated with specific diseases of all livestock species, at 20–45%. During gestation processes, a series of complex alterations can arise, including embryonic migration and elongation, maternal immunological recognition of pregnancy, and embryonic competition for implantation sites and subsequent nutrition requirements and development. Immune cells and cytokines act as mediators between other molecules in highly complex interactions between various cell types. However, other non-immune cells, such as trophoblast cells, are important in immune pregnancy regulation. Numerous studies have shed light on the crucial roles of several cytokines that regulate the inflammatory processes that characterize the interface between the fetus and the mother throughout normal porcine gestation, but most of these reports are limited to the implantational and peri-implantational periods. Increase in some proinflammatory cytokines have been found in other gestational periods, such as placental remodeling. Porcine immune changes during delivery have not been studied as deeply as in other species. This review details some of the immune system cells actively involved in the fetomaternal interface during porcine gestation, as well as the principal cells, cytokines, and molecules, such as antibodies, that play crucial roles in sow pregnancy, both in early and mid-to-late gestation.
publishDate 2024
dc.date.none.fl_str_mv 2024-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/230937
Velez, Carolina; Williamson, Delia Maria; Canovas, Mariela Lorena; Giai, Laura Romina; Rutland, Catrin; et al.; Changes in immune response during pig gestation with a focus on cytokines; Multidisciplinary Digital Publishing Institute; Veterinary Sciences; 11; 1; 1-2024; 1-24
2306-7381
CONICET Digital
CONICET
url http://hdl.handle.net/11336/230937
identifier_str_mv Velez, Carolina; Williamson, Delia Maria; Canovas, Mariela Lorena; Giai, Laura Romina; Rutland, Catrin; et al.; Changes in immune response during pig gestation with a focus on cytokines; Multidisciplinary Digital Publishing Institute; Veterinary Sciences; 11; 1; 1-2024; 1-24
2306-7381
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/vetsci11010050
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2306-7381/11/1/50
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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