The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy

Autores
Lucangioli, Silvia Edith; Tripodi, Valeria Paula
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This report describes the response of a patient treated with two different coenzyme Q10 extemporaneous pharmaceutical formulations that generated radical changes in her symptoms and life quality. It could explain why in some cases therapy with coenzyme Q10 does not work in patients with deficiency of this coenzyme. It is important that the scientific community dedicated to the area of health be aware and mindful of differences that can occur in extemporaneous preparations which are not as strict at the time of development and control as in pharmaceutical industry. The aim of this study was to demonstrate the need for extreme control in the coenzyme Q10 formulation administered to patients.
Fil: Lucangioli, Silvia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina
Fil: Tripodi, Valeria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina
Materia
COENZYME Q10
FORMULATION
MITOCHONDRIAL DISEASE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/217395
Acceder
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network_name_str CONICET Digital (CONICET)
spelling The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapyLucangioli, Silvia EdithTripodi, Valeria PaulaCOENZYME Q10FORMULATIONMITOCHONDRIAL DISEASEhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3This report describes the response of a patient treated with two different coenzyme Q10 extemporaneous pharmaceutical formulations that generated radical changes in her symptoms and life quality. It could explain why in some cases therapy with coenzyme Q10 does not work in patients with deficiency of this coenzyme. It is important that the scientific community dedicated to the area of health be aware and mindful of differences that can occur in extemporaneous preparations which are not as strict at the time of development and control as in pharmaceutical industry. The aim of this study was to demonstrate the need for extreme control in the coenzyme Q10 formulation administered to patients.Fil: Lucangioli, Silvia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaFil: Tripodi, Valeria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaPelagia Research Library2012-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/217395Lucangioli, Silvia Edith; Tripodi, Valeria Paula; The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy; Pelagia Research Library; Der Pharmacia Sinica; 3; 4; 8-2012; 406-4070976-8688CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.imedpub.com/articles/the-importance-of-the-formulation-in-the-effectiveness-of-coenzyme-q10-supplementation-in-mitochondrial-disease-therapy.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:55:23Zoai:ri.conicet.gov.ar:11336/217395instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:55:23.6CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
title The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
spellingShingle The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
Lucangioli, Silvia Edith
COENZYME Q10
FORMULATION
MITOCHONDRIAL DISEASE
title_short The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
title_full The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
title_fullStr The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
title_full_unstemmed The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
title_sort The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy
dc.creator.none.fl_str_mv Lucangioli, Silvia Edith
Tripodi, Valeria Paula
author Lucangioli, Silvia Edith
author_facet Lucangioli, Silvia Edith
Tripodi, Valeria Paula
author_role author
author2 Tripodi, Valeria Paula
author2_role author
dc.subject.none.fl_str_mv COENZYME Q10
FORMULATION
MITOCHONDRIAL DISEASE
topic COENZYME Q10
FORMULATION
MITOCHONDRIAL DISEASE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv This report describes the response of a patient treated with two different coenzyme Q10 extemporaneous pharmaceutical formulations that generated radical changes in her symptoms and life quality. It could explain why in some cases therapy with coenzyme Q10 does not work in patients with deficiency of this coenzyme. It is important that the scientific community dedicated to the area of health be aware and mindful of differences that can occur in extemporaneous preparations which are not as strict at the time of development and control as in pharmaceutical industry. The aim of this study was to demonstrate the need for extreme control in the coenzyme Q10 formulation administered to patients.
Fil: Lucangioli, Silvia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina
Fil: Tripodi, Valeria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina
description This report describes the response of a patient treated with two different coenzyme Q10 extemporaneous pharmaceutical formulations that generated radical changes in her symptoms and life quality. It could explain why in some cases therapy with coenzyme Q10 does not work in patients with deficiency of this coenzyme. It is important that the scientific community dedicated to the area of health be aware and mindful of differences that can occur in extemporaneous preparations which are not as strict at the time of development and control as in pharmaceutical industry. The aim of this study was to demonstrate the need for extreme control in the coenzyme Q10 formulation administered to patients.
publishDate 2012
dc.date.none.fl_str_mv 2012-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/217395
Lucangioli, Silvia Edith; Tripodi, Valeria Paula; The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy; Pelagia Research Library; Der Pharmacia Sinica; 3; 4; 8-2012; 406-407
0976-8688
CONICET Digital
CONICET
url http://hdl.handle.net/11336/217395
identifier_str_mv Lucangioli, Silvia Edith; Tripodi, Valeria Paula; The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy; Pelagia Research Library; Der Pharmacia Sinica; 3; 4; 8-2012; 406-407
0976-8688
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.imedpub.com/articles/the-importance-of-the-formulation-in-the-effectiveness-of-coenzyme-q10-supplementation-in-mitochondrial-disease-therapy.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pelagia Research Library
publisher.none.fl_str_mv Pelagia Research Library
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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