Penetration enhancers for the development of intranasal formulations for use in equines

Autores
Velloso, María Inés; Landoni, Maria Fabiana
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this review is to assess penetration enhancers, such as cyclodextrins, chitosan and their derivatives, surfactants, bileacids, their salts and derivatives, sodium taurodihidrydrofusidate, and phospholipids used in the development of intranasalformulations with a potential application in horses. In the last few years, the interest in the intranasal administration routein humans has grown because it is bloodless, noninvasive, and painless and represents a direct path toward the centralnervous system. However, in equine medicine, the use of this administration route is scarce. Since equines have a nasal cavitywith large surface area and blood irrigation, a high bioavailability of intranasal administered drugs is expected. Nowadays,the development of formulations for intranasal administration in equines is a challenge. The present review proposes theassessment of the characteristics and potential effects of the most important penetration enhancers in the development ofintranasal formulations for use in equines.
Fil: Velloso, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
Fil: Landoni, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
Materia
HORSES
CYCLODEXTRINS
CHITOSAN
SURFACTANTS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/188262
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Penetration enhancers for the development of intranasal formulations for use in equinesVelloso, María InésLandoni, Maria FabianaHORSESCYCLODEXTRINSCHITOSANSURFACTANTShttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4The aim of this review is to assess penetration enhancers, such as cyclodextrins, chitosan and their derivatives, surfactants, bileacids, their salts and derivatives, sodium taurodihidrydrofusidate, and phospholipids used in the development of intranasalformulations with a potential application in horses. In the last few years, the interest in the intranasal administration routein humans has grown because it is bloodless, noninvasive, and painless and represents a direct path toward the centralnervous system. However, in equine medicine, the use of this administration route is scarce. Since equines have a nasal cavitywith large surface area and blood irrigation, a high bioavailability of intranasal administered drugs is expected. Nowadays,the development of formulations for intranasal administration in equines is a challenge. The present review proposes theassessment of the characteristics and potential effects of the most important penetration enhancers in the development ofintranasal formulations for use in equines.Fil: Velloso, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; ArgentinaFil: Landoni, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; ArgentinaRasayely2022-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/188262Velloso, María Inés; Landoni, Maria Fabiana; Penetration enhancers for the development of intranasal formulations for use in equines; Rasayely; International Journal of Equine Science; 1; 1; 3-2022; 16-322805-31092805-3117CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://rasayely-journals.com/index.php/ijes/article/view/9info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:00:46Zoai:ri.conicet.gov.ar:11336/188262instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:00:46.567CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Penetration enhancers for the development of intranasal formulations for use in equines
title Penetration enhancers for the development of intranasal formulations for use in equines
spellingShingle Penetration enhancers for the development of intranasal formulations for use in equines
Velloso, María Inés
HORSES
CYCLODEXTRINS
CHITOSAN
SURFACTANTS
title_short Penetration enhancers for the development of intranasal formulations for use in equines
title_full Penetration enhancers for the development of intranasal formulations for use in equines
title_fullStr Penetration enhancers for the development of intranasal formulations for use in equines
title_full_unstemmed Penetration enhancers for the development of intranasal formulations for use in equines
title_sort Penetration enhancers for the development of intranasal formulations for use in equines
dc.creator.none.fl_str_mv Velloso, María Inés
Landoni, Maria Fabiana
author Velloso, María Inés
author_facet Velloso, María Inés
Landoni, Maria Fabiana
author_role author
author2 Landoni, Maria Fabiana
author2_role author
dc.subject.none.fl_str_mv HORSES
CYCLODEXTRINS
CHITOSAN
SURFACTANTS
topic HORSES
CYCLODEXTRINS
CHITOSAN
SURFACTANTS
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv The aim of this review is to assess penetration enhancers, such as cyclodextrins, chitosan and their derivatives, surfactants, bileacids, their salts and derivatives, sodium taurodihidrydrofusidate, and phospholipids used in the development of intranasalformulations with a potential application in horses. In the last few years, the interest in the intranasal administration routein humans has grown because it is bloodless, noninvasive, and painless and represents a direct path toward the centralnervous system. However, in equine medicine, the use of this administration route is scarce. Since equines have a nasal cavitywith large surface area and blood irrigation, a high bioavailability of intranasal administered drugs is expected. Nowadays,the development of formulations for intranasal administration in equines is a challenge. The present review proposes theassessment of the characteristics and potential effects of the most important penetration enhancers in the development ofintranasal formulations for use in equines.
Fil: Velloso, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
Fil: Landoni, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
description The aim of this review is to assess penetration enhancers, such as cyclodextrins, chitosan and their derivatives, surfactants, bileacids, their salts and derivatives, sodium taurodihidrydrofusidate, and phospholipids used in the development of intranasalformulations with a potential application in horses. In the last few years, the interest in the intranasal administration routein humans has grown because it is bloodless, noninvasive, and painless and represents a direct path toward the centralnervous system. However, in equine medicine, the use of this administration route is scarce. Since equines have a nasal cavitywith large surface area and blood irrigation, a high bioavailability of intranasal administered drugs is expected. Nowadays,the development of formulations for intranasal administration in equines is a challenge. The present review proposes theassessment of the characteristics and potential effects of the most important penetration enhancers in the development ofintranasal formulations for use in equines.
publishDate 2022
dc.date.none.fl_str_mv 2022-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/188262
Velloso, María Inés; Landoni, Maria Fabiana; Penetration enhancers for the development of intranasal formulations for use in equines; Rasayely; International Journal of Equine Science; 1; 1; 3-2022; 16-32
2805-3109
2805-3117
CONICET Digital
CONICET
url http://hdl.handle.net/11336/188262
identifier_str_mv Velloso, María Inés; Landoni, Maria Fabiana; Penetration enhancers for the development of intranasal formulations for use in equines; Rasayely; International Journal of Equine Science; 1; 1; 3-2022; 16-32
2805-3109
2805-3117
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://rasayely-journals.com/index.php/ijes/article/view/9
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Rasayely
publisher.none.fl_str_mv Rasayely
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269658127794176
score 13.13397

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