Role of Hydration in Biomembranes as a Challenge for Current Biophysics

Autores
Disalvo, Edgardo Anibal; Cejas, Jimena del Pilar; Rosa, Antonio Sebastián; Frias, Maria de Los Angeles
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The consideration of water as a structural component gives biological membranes specific thermodynamic properties that explain its responsive behavior when chased by physical and chemical perturbations. These properties are derived from the peculiar surface tension of pure water and its variation due to the presence of hydrogen bonds arrangements between water and membrane components that determine a complex surface free energy profile. A completer and more realistic picture should consider how the hydration properties are linked to mechanical forces with relevance in osmotic stress of cells and in the behavior lipid monolayers. In the present work, the mechano-chemical coupling of surface pressure with water activity in a lipid interphase is explored as a way to mimic the thermodynamic response of the lipid interphase to bioactive compounds. As a result, the relaxation processes during the action of bio effectors are described in terms of water organization around the lipid residues such as acyl chains and polar head groups.
Fil: Disalvo, Edgardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Cejas, Jimena del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Rosa, Antonio Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Frias, Maria de Los Angeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Materia
LIPID MEMBRANES
HYDRATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/181641
Acceder
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spelling Role of Hydration in Biomembranes as a Challenge for Current BiophysicsDisalvo, Edgardo AnibalCejas, Jimena del PilarRosa, Antonio SebastiánFrias, Maria de Los AngelesLIPID MEMBRANESHYDRATIONhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The consideration of water as a structural component gives biological membranes specific thermodynamic properties that explain its responsive behavior when chased by physical and chemical perturbations. These properties are derived from the peculiar surface tension of pure water and its variation due to the presence of hydrogen bonds arrangements between water and membrane components that determine a complex surface free energy profile. A completer and more realistic picture should consider how the hydration properties are linked to mechanical forces with relevance in osmotic stress of cells and in the behavior lipid monolayers. In the present work, the mechano-chemical coupling of surface pressure with water activity in a lipid interphase is explored as a way to mimic the thermodynamic response of the lipid interphase to bioactive compounds. As a result, the relaxation processes during the action of bio effectors are described in terms of water organization around the lipid residues such as acyl chains and polar head groups.Fil: Disalvo, Edgardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; ArgentinaFil: Cejas, Jimena del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; ArgentinaFil: Rosa, Antonio Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; ArgentinaFil: Frias, Maria de Los Angeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; ArgentinaCrimson Publishers2021-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/181641Disalvo, Edgardo Anibal; Cejas, Jimena del Pilar; Rosa, Antonio Sebastián; Frias, Maria de Los Angeles; Role of Hydration in Biomembranes as a Challenge for Current Biophysics; Crimson Publishers; COJ Reviews and Research; 3; 2; 7-2021; 1-52639-0590CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.31031/COJRR.2021.03.000559info:eu-repo/semantics/altIdentifier/url/https://crimsonpublishers.com/cojrr/fulltext/COJRR.000559.phpinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:39:47Zoai:ri.conicet.gov.ar:11336/181641instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:39:47.954CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Role of Hydration in Biomembranes as a Challenge for Current Biophysics
title Role of Hydration in Biomembranes as a Challenge for Current Biophysics
spellingShingle Role of Hydration in Biomembranes as a Challenge for Current Biophysics
Disalvo, Edgardo Anibal
LIPID MEMBRANES
HYDRATION
title_short Role of Hydration in Biomembranes as a Challenge for Current Biophysics
title_full Role of Hydration in Biomembranes as a Challenge for Current Biophysics
title_fullStr Role of Hydration in Biomembranes as a Challenge for Current Biophysics
title_full_unstemmed Role of Hydration in Biomembranes as a Challenge for Current Biophysics
title_sort Role of Hydration in Biomembranes as a Challenge for Current Biophysics
dc.creator.none.fl_str_mv Disalvo, Edgardo Anibal
Cejas, Jimena del Pilar
Rosa, Antonio Sebastián
Frias, Maria de Los Angeles
author Disalvo, Edgardo Anibal
author_facet Disalvo, Edgardo Anibal
Cejas, Jimena del Pilar
Rosa, Antonio Sebastián
Frias, Maria de Los Angeles
author_role author
author2 Cejas, Jimena del Pilar
Rosa, Antonio Sebastián
Frias, Maria de Los Angeles
author2_role author
author
author
dc.subject.none.fl_str_mv LIPID MEMBRANES
HYDRATION
topic LIPID MEMBRANES
HYDRATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The consideration of water as a structural component gives biological membranes specific thermodynamic properties that explain its responsive behavior when chased by physical and chemical perturbations. These properties are derived from the peculiar surface tension of pure water and its variation due to the presence of hydrogen bonds arrangements between water and membrane components that determine a complex surface free energy profile. A completer and more realistic picture should consider how the hydration properties are linked to mechanical forces with relevance in osmotic stress of cells and in the behavior lipid monolayers. In the present work, the mechano-chemical coupling of surface pressure with water activity in a lipid interphase is explored as a way to mimic the thermodynamic response of the lipid interphase to bioactive compounds. As a result, the relaxation processes during the action of bio effectors are described in terms of water organization around the lipid residues such as acyl chains and polar head groups.
Fil: Disalvo, Edgardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Cejas, Jimena del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Rosa, Antonio Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Frias, Maria de Los Angeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
description The consideration of water as a structural component gives biological membranes specific thermodynamic properties that explain its responsive behavior when chased by physical and chemical perturbations. These properties are derived from the peculiar surface tension of pure water and its variation due to the presence of hydrogen bonds arrangements between water and membrane components that determine a complex surface free energy profile. A completer and more realistic picture should consider how the hydration properties are linked to mechanical forces with relevance in osmotic stress of cells and in the behavior lipid monolayers. In the present work, the mechano-chemical coupling of surface pressure with water activity in a lipid interphase is explored as a way to mimic the thermodynamic response of the lipid interphase to bioactive compounds. As a result, the relaxation processes during the action of bio effectors are described in terms of water organization around the lipid residues such as acyl chains and polar head groups.
publishDate 2021
dc.date.none.fl_str_mv 2021-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/181641
Disalvo, Edgardo Anibal; Cejas, Jimena del Pilar; Rosa, Antonio Sebastián; Frias, Maria de Los Angeles; Role of Hydration in Biomembranes as a Challenge for Current Biophysics; Crimson Publishers; COJ Reviews and Research; 3; 2; 7-2021; 1-5
2639-0590
CONICET Digital
CONICET
url http://hdl.handle.net/11336/181641
identifier_str_mv Disalvo, Edgardo Anibal; Cejas, Jimena del Pilar; Rosa, Antonio Sebastián; Frias, Maria de Los Angeles; Role of Hydration in Biomembranes as a Challenge for Current Biophysics; Crimson Publishers; COJ Reviews and Research; 3; 2; 7-2021; 1-5
2639-0590
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.31031/COJRR.2021.03.000559
info:eu-repo/semantics/altIdentifier/url/https://crimsonpublishers.com/cojrr/fulltext/COJRR.000559.php
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Crimson Publishers
publisher.none.fl_str_mv Crimson Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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