Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina
- Autores
- Butinof, Mariana; Fernández, Ricardo A.; Lerda, Daniel; Lantieri, María Josefina; Filippi, Iohanna; Díaz, María del Pilar
- Año de publicación
- 2019
- Idioma
- español castellano
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Objective: To assess the level of exposure to pesticides and its correlation with perceived health indicators and injury biomarkers (genotoxic alterations and those caused by butyrylcholinesterase enzyme activity) in the population of pesticide applicators in extensive crops (PAEC) in Córdoba, Argentina. Methods: Transversal study, in PAEC (n = 47) randomly selected from a sample of 2000, and non-exposed subject controls (n = 52). The sociodemographic variables, exposure conditioning, and perceived health were surveyed by means of a self-administered questionnaire; biological indicators of genotoxicity: micronuclei, chromosomal aberrations and kite assay, and butyrylcholinesterase activity. Results: 40% of PAEC have over 10 years’ length of service and almost 50% of them reside less than 500 m from the sprinkled fields; they report low rates of personal protective equipment use while mixing, applying, or repairing the equipment. General, cardio-respiratory, and dermatological symptoms were greater among PAEC (p <0.05) as well as indicators of genotoxic injury (p <0.001). The butyrylcholinesterase activity was negatively associated with levels of exposure to pesticides. Conclusions: The PAEC show an important negative impact on health linked to exposure to pesticides. The exposure scales associated to the use of biomarkers were a useful tool for monitoring pesticide applicators’ health.
Fil: Butinof, Mariana. Universidad Nacional de Cordoba. Facultad de Medicina. Escuela de Nutrición; Argentina
Fil: Fernández, Ricardo A.. Universidad Católica de Córdoba. Facultad de Medicina; Argentina
Fil: Lerda, Daniel. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Lantieri, María Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina
Fil: Filippi, Iohanna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Díaz, María del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Cordoba. Facultad de Medicina. Escuela de Nutrición; Argentina - Materia
-
ARGENTINA
BIOMONITORING
EPIDEMIOLOGICAL SURVEILLANCE
PESTICIDE APPLICATORS
PESTICIDE EXPOSURE - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/95617
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Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, ArgentinaBiomonitoring in exposure to pesticides, its contribution to epidemiological surveillance of pesticide applicators in Cordoba, ArgentinaButinof, MarianaFernández, Ricardo A.Lerda, DanielLantieri, María JosefinaFilippi, IohannaDíaz, María del PilarARGENTINABIOMONITORINGEPIDEMIOLOGICAL SURVEILLANCEPESTICIDE APPLICATORSPESTICIDE EXPOSUREhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Objective: To assess the level of exposure to pesticides and its correlation with perceived health indicators and injury biomarkers (genotoxic alterations and those caused by butyrylcholinesterase enzyme activity) in the population of pesticide applicators in extensive crops (PAEC) in Córdoba, Argentina. Methods: Transversal study, in PAEC (n = 47) randomly selected from a sample of 2000, and non-exposed subject controls (n = 52). The sociodemographic variables, exposure conditioning, and perceived health were surveyed by means of a self-administered questionnaire; biological indicators of genotoxicity: micronuclei, chromosomal aberrations and kite assay, and butyrylcholinesterase activity. Results: 40% of PAEC have over 10 years’ length of service and almost 50% of them reside less than 500 m from the sprinkled fields; they report low rates of personal protective equipment use while mixing, applying, or repairing the equipment. General, cardio-respiratory, and dermatological symptoms were greater among PAEC (p <0.05) as well as indicators of genotoxic injury (p <0.001). The butyrylcholinesterase activity was negatively associated with levels of exposure to pesticides. Conclusions: The PAEC show an important negative impact on health linked to exposure to pesticides. The exposure scales associated to the use of biomarkers were a useful tool for monitoring pesticide applicators’ health.Fil: Butinof, Mariana. Universidad Nacional de Cordoba. Facultad de Medicina. Escuela de Nutrición; ArgentinaFil: Fernández, Ricardo A.. Universidad Católica de Córdoba. Facultad de Medicina; ArgentinaFil: Lerda, Daniel. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Lantieri, María Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina; ArgentinaFil: Filippi, Iohanna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Díaz, María del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Cordoba. Facultad de Medicina. Escuela de Nutrición; ArgentinaElsevier2019-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/95617Butinof, Mariana; Fernández, Ricardo A.; Lerda, Daniel; Lantieri, María Josefina; Filippi, Iohanna; et al.; Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina; Elsevier; Gaceta Sanitaria; 33; 3; 5-2019; 216-2210213-9111CONICET DigitalCONICETspainfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0213911118300165info:eu-repo/semantics/altIdentifier/doi/10.1016/j.gaceta.2017.12.002info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:35:58Zoai:ri.conicet.gov.ar:11336/95617instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:35:58.751CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina Biomonitoring in exposure to pesticides, its contribution to epidemiological surveillance of pesticide applicators in Cordoba, Argentina |
title |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina |
spellingShingle |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina Butinof, Mariana ARGENTINA BIOMONITORING EPIDEMIOLOGICAL SURVEILLANCE PESTICIDE APPLICATORS PESTICIDE EXPOSURE |
title_short |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina |
title_full |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina |
title_fullStr |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina |
title_full_unstemmed |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina |
title_sort |
Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina |
dc.creator.none.fl_str_mv |
Butinof, Mariana Fernández, Ricardo A. Lerda, Daniel Lantieri, María Josefina Filippi, Iohanna Díaz, María del Pilar |
author |
Butinof, Mariana |
author_facet |
Butinof, Mariana Fernández, Ricardo A. Lerda, Daniel Lantieri, María Josefina Filippi, Iohanna Díaz, María del Pilar |
author_role |
author |
author2 |
Fernández, Ricardo A. Lerda, Daniel Lantieri, María Josefina Filippi, Iohanna Díaz, María del Pilar |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
ARGENTINA BIOMONITORING EPIDEMIOLOGICAL SURVEILLANCE PESTICIDE APPLICATORS PESTICIDE EXPOSURE |
topic |
ARGENTINA BIOMONITORING EPIDEMIOLOGICAL SURVEILLANCE PESTICIDE APPLICATORS PESTICIDE EXPOSURE |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Objective: To assess the level of exposure to pesticides and its correlation with perceived health indicators and injury biomarkers (genotoxic alterations and those caused by butyrylcholinesterase enzyme activity) in the population of pesticide applicators in extensive crops (PAEC) in Córdoba, Argentina. Methods: Transversal study, in PAEC (n = 47) randomly selected from a sample of 2000, and non-exposed subject controls (n = 52). The sociodemographic variables, exposure conditioning, and perceived health were surveyed by means of a self-administered questionnaire; biological indicators of genotoxicity: micronuclei, chromosomal aberrations and kite assay, and butyrylcholinesterase activity. Results: 40% of PAEC have over 10 years’ length of service and almost 50% of them reside less than 500 m from the sprinkled fields; they report low rates of personal protective equipment use while mixing, applying, or repairing the equipment. General, cardio-respiratory, and dermatological symptoms were greater among PAEC (p <0.05) as well as indicators of genotoxic injury (p <0.001). The butyrylcholinesterase activity was negatively associated with levels of exposure to pesticides. Conclusions: The PAEC show an important negative impact on health linked to exposure to pesticides. The exposure scales associated to the use of biomarkers were a useful tool for monitoring pesticide applicators’ health. Fil: Butinof, Mariana. Universidad Nacional de Cordoba. Facultad de Medicina. Escuela de Nutrición; Argentina Fil: Fernández, Ricardo A.. Universidad Católica de Córdoba. Facultad de Medicina; Argentina Fil: Lerda, Daniel. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Lantieri, María Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina Fil: Filippi, Iohanna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Díaz, María del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Cordoba. Facultad de Medicina. Escuela de Nutrición; Argentina |
description |
Objective: To assess the level of exposure to pesticides and its correlation with perceived health indicators and injury biomarkers (genotoxic alterations and those caused by butyrylcholinesterase enzyme activity) in the population of pesticide applicators in extensive crops (PAEC) in Córdoba, Argentina. Methods: Transversal study, in PAEC (n = 47) randomly selected from a sample of 2000, and non-exposed subject controls (n = 52). The sociodemographic variables, exposure conditioning, and perceived health were surveyed by means of a self-administered questionnaire; biological indicators of genotoxicity: micronuclei, chromosomal aberrations and kite assay, and butyrylcholinesterase activity. Results: 40% of PAEC have over 10 years’ length of service and almost 50% of them reside less than 500 m from the sprinkled fields; they report low rates of personal protective equipment use while mixing, applying, or repairing the equipment. General, cardio-respiratory, and dermatological symptoms were greater among PAEC (p <0.05) as well as indicators of genotoxic injury (p <0.001). The butyrylcholinesterase activity was negatively associated with levels of exposure to pesticides. Conclusions: The PAEC show an important negative impact on health linked to exposure to pesticides. The exposure scales associated to the use of biomarkers were a useful tool for monitoring pesticide applicators’ health. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-05 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/95617 Butinof, Mariana; Fernández, Ricardo A.; Lerda, Daniel; Lantieri, María Josefina; Filippi, Iohanna; et al.; Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina; Elsevier; Gaceta Sanitaria; 33; 3; 5-2019; 216-221 0213-9111 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/95617 |
identifier_str_mv |
Butinof, Mariana; Fernández, Ricardo A.; Lerda, Daniel; Lantieri, María Josefina; Filippi, Iohanna; et al.; Biomonitoreo en exposición a plaguicidas y su aporte en vigilancia epidemiológica en agroaplicadores en Córdoba, Argentina; Elsevier; Gaceta Sanitaria; 33; 3; 5-2019; 216-221 0213-9111 CONICET Digital CONICET |
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spa |
language |
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info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0213911118300165 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.gaceta.2017.12.002 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
eu_rights_str_mv |
openAccess |
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https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
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application/pdf application/pdf application/pdf |
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Elsevier |
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Elsevier |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |