In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia

Autores
Russo, Maria Paula; Marquez Fosser, Santiago Nicolas; Elizondo, Cristina María; Giunta, Diego Hernan; Fuentes, Nora Angéelica; Grande Ratti, Maria Florencia
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to make a proper diabetes diagnosis if hospitalized patients with episodes of hyperglycemia with and without diabetes are studied. AIMS: To estimate the extent of the association between stress-induced hyperglycemia and in-hospital mortality in patients with hospital hyperglycemia (HH), and to explore potential differences between patients diagnosed with diabetes (HH-DBT) and those with stress-induced hyperglycemia (SH), but not diagnosed with diabetes. METHODS: A cohort of adults with hospital hyperglycemia admitted to a tertiary, university hospital in Buenos Aires, Argentina, was analyzed retrospectively. RESULTS: In the study, 2,955 patients were included and classified for analysis as 1,579 SH and 1,376 HH-DBT. Significant differences were observed in glycemic goal (35.53% SH versus 25.80% HH-DBT, p < 0.01), insulin use rate (26.66% SH versus 46.58% HH-DBT, p < 0.01), and severe hypoglycemia rate (1.32% SH versus 1.74% HH-DBT, p < 0.01). There were no differences in hypoglycemia rate (8.23% SH versus 10.53% HH-DBT) and hospital mortality. There was no increase in risk of mortality in the SH group adjusted for age, non-scheduled hospitalization, major surgical intervention, critical care, hypoglycemia, oncological disease, cardiovascular comorbidity, and prolonged hospitalization. CONCLUSIONS: In this study, we observed better glycemic control in patients with SH than in those with HH-DBT, and there was no difference in hospital mortality.
Fil: Russo, Maria Paula. Hospital Italiano; Argentina
Fil: Marquez Fosser, Santiago Nicolas. Hospital Italiano; Argentina. McGill University; Canadá
Fil: Elizondo, Cristina María. Hospital Italiano; Argentina
Fil: Giunta, Diego Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Italiano; Argentina
Fil: Fuentes, Nora Angéelica. Hospital Italiano; Argentina
Fil: Grande Ratti, Maria Florencia. Hospital Italiano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
HOSPITAL HYPERGLYCEMIA
HOSPITAL HYPERGLYCEMIA
HOSPITAL MORTALITY
STRESS HYPERGLYCEMIA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/216544
Acceder
id CONICETDig_1cddaf510559681c78ccdec57f40499e
oai_identifier_str oai:ri.conicet.gov.ar:11336/216544
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling In-Hospital Mortality and Glycemic Control in Patients with Hospital HyperglycemiaRusso, Maria PaulaMarquez Fosser, Santiago NicolasElizondo, Cristina MaríaGiunta, Diego HernanFuentes, Nora AngéelicaGrande Ratti, Maria FlorenciaHOSPITAL HYPERGLYCEMIAHOSPITAL HYPERGLYCEMIAHOSPITAL MORTALITYSTRESS HYPERGLYCEMIAhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to make a proper diabetes diagnosis if hospitalized patients with episodes of hyperglycemia with and without diabetes are studied. AIMS: To estimate the extent of the association between stress-induced hyperglycemia and in-hospital mortality in patients with hospital hyperglycemia (HH), and to explore potential differences between patients diagnosed with diabetes (HH-DBT) and those with stress-induced hyperglycemia (SH), but not diagnosed with diabetes. METHODS: A cohort of adults with hospital hyperglycemia admitted to a tertiary, university hospital in Buenos Aires, Argentina, was analyzed retrospectively. RESULTS: In the study, 2,955 patients were included and classified for analysis as 1,579 SH and 1,376 HH-DBT. Significant differences were observed in glycemic goal (35.53% SH versus 25.80% HH-DBT, p < 0.01), insulin use rate (26.66% SH versus 46.58% HH-DBT, p < 0.01), and severe hypoglycemia rate (1.32% SH versus 1.74% HH-DBT, p < 0.01). There were no differences in hypoglycemia rate (8.23% SH versus 10.53% HH-DBT) and hospital mortality. There was no increase in risk of mortality in the SH group adjusted for age, non-scheduled hospitalization, major surgical intervention, critical care, hypoglycemia, oncological disease, cardiovascular comorbidity, and prolonged hospitalization. CONCLUSIONS: In this study, we observed better glycemic control in patients with SH than in those with HH-DBT, and there was no difference in hospital mortality.Fil: Russo, Maria Paula. Hospital Italiano; ArgentinaFil: Marquez Fosser, Santiago Nicolas. Hospital Italiano; Argentina. McGill University; CanadáFil: Elizondo, Cristina María. Hospital Italiano; ArgentinaFil: Giunta, Diego Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Italiano; ArgentinaFil: Fuentes, Nora Angéelica. Hospital Italiano; ArgentinaFil: Grande Ratti, Maria Florencia. Hospital Italiano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaSociety for Biomedical Diabetes Research2021-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/216544Russo, Maria Paula; Marquez Fosser, Santiago Nicolas; Elizondo, Cristina María; Giunta, Diego Hernan; Fuentes, Nora Angéelica; et al.; In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia; Society for Biomedical Diabetes Research; Review of Diabetic Studies; 17; 2; 11-2021; 50-561613-60711614-0575CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1900/RDS.2021.17.50info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:18:59Zoai:ri.conicet.gov.ar:11336/216544instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:18:59.523CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
title In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
spellingShingle In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
Russo, Maria Paula
HOSPITAL HYPERGLYCEMIA
HOSPITAL HYPERGLYCEMIA
HOSPITAL MORTALITY
STRESS HYPERGLYCEMIA
title_short In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
title_full In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
title_fullStr In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
title_full_unstemmed In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
title_sort In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
dc.creator.none.fl_str_mv Russo, Maria Paula
Marquez Fosser, Santiago Nicolas
Elizondo, Cristina María
Giunta, Diego Hernan
Fuentes, Nora Angéelica
Grande Ratti, Maria Florencia
author Russo, Maria Paula
author_facet Russo, Maria Paula
Marquez Fosser, Santiago Nicolas
Elizondo, Cristina María
Giunta, Diego Hernan
Fuentes, Nora Angéelica
Grande Ratti, Maria Florencia
author_role author
author2 Marquez Fosser, Santiago Nicolas
Elizondo, Cristina María
Giunta, Diego Hernan
Fuentes, Nora Angéelica
Grande Ratti, Maria Florencia
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv HOSPITAL HYPERGLYCEMIA
HOSPITAL HYPERGLYCEMIA
HOSPITAL MORTALITY
STRESS HYPERGLYCEMIA
topic HOSPITAL HYPERGLYCEMIA
HOSPITAL HYPERGLYCEMIA
HOSPITAL MORTALITY
STRESS HYPERGLYCEMIA
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to make a proper diabetes diagnosis if hospitalized patients with episodes of hyperglycemia with and without diabetes are studied. AIMS: To estimate the extent of the association between stress-induced hyperglycemia and in-hospital mortality in patients with hospital hyperglycemia (HH), and to explore potential differences between patients diagnosed with diabetes (HH-DBT) and those with stress-induced hyperglycemia (SH), but not diagnosed with diabetes. METHODS: A cohort of adults with hospital hyperglycemia admitted to a tertiary, university hospital in Buenos Aires, Argentina, was analyzed retrospectively. RESULTS: In the study, 2,955 patients were included and classified for analysis as 1,579 SH and 1,376 HH-DBT. Significant differences were observed in glycemic goal (35.53% SH versus 25.80% HH-DBT, p < 0.01), insulin use rate (26.66% SH versus 46.58% HH-DBT, p < 0.01), and severe hypoglycemia rate (1.32% SH versus 1.74% HH-DBT, p < 0.01). There were no differences in hypoglycemia rate (8.23% SH versus 10.53% HH-DBT) and hospital mortality. There was no increase in risk of mortality in the SH group adjusted for age, non-scheduled hospitalization, major surgical intervention, critical care, hypoglycemia, oncological disease, cardiovascular comorbidity, and prolonged hospitalization. CONCLUSIONS: In this study, we observed better glycemic control in patients with SH than in those with HH-DBT, and there was no difference in hospital mortality.
Fil: Russo, Maria Paula. Hospital Italiano; Argentina
Fil: Marquez Fosser, Santiago Nicolas. Hospital Italiano; Argentina. McGill University; Canadá
Fil: Elizondo, Cristina María. Hospital Italiano; Argentina
Fil: Giunta, Diego Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Italiano; Argentina
Fil: Fuentes, Nora Angéelica. Hospital Italiano; Argentina
Fil: Grande Ratti, Maria Florencia. Hospital Italiano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to make a proper diabetes diagnosis if hospitalized patients with episodes of hyperglycemia with and without diabetes are studied. AIMS: To estimate the extent of the association between stress-induced hyperglycemia and in-hospital mortality in patients with hospital hyperglycemia (HH), and to explore potential differences between patients diagnosed with diabetes (HH-DBT) and those with stress-induced hyperglycemia (SH), but not diagnosed with diabetes. METHODS: A cohort of adults with hospital hyperglycemia admitted to a tertiary, university hospital in Buenos Aires, Argentina, was analyzed retrospectively. RESULTS: In the study, 2,955 patients were included and classified for analysis as 1,579 SH and 1,376 HH-DBT. Significant differences were observed in glycemic goal (35.53% SH versus 25.80% HH-DBT, p < 0.01), insulin use rate (26.66% SH versus 46.58% HH-DBT, p < 0.01), and severe hypoglycemia rate (1.32% SH versus 1.74% HH-DBT, p < 0.01). There were no differences in hypoglycemia rate (8.23% SH versus 10.53% HH-DBT) and hospital mortality. There was no increase in risk of mortality in the SH group adjusted for age, non-scheduled hospitalization, major surgical intervention, critical care, hypoglycemia, oncological disease, cardiovascular comorbidity, and prolonged hospitalization. CONCLUSIONS: In this study, we observed better glycemic control in patients with SH than in those with HH-DBT, and there was no difference in hospital mortality.
publishDate 2021
dc.date.none.fl_str_mv 2021-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/216544
Russo, Maria Paula; Marquez Fosser, Santiago Nicolas; Elizondo, Cristina María; Giunta, Diego Hernan; Fuentes, Nora Angéelica; et al.; In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia; Society for Biomedical Diabetes Research; Review of Diabetic Studies; 17; 2; 11-2021; 50-56
1613-6071
1614-0575
CONICET Digital
CONICET
url http://hdl.handle.net/11336/216544
identifier_str_mv Russo, Maria Paula; Marquez Fosser, Santiago Nicolas; Elizondo, Cristina María; Giunta, Diego Hernan; Fuentes, Nora Angéelica; et al.; In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia; Society for Biomedical Diabetes Research; Review of Diabetic Studies; 17; 2; 11-2021; 50-56
1613-6071
1614-0575
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1900/RDS.2021.17.50
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Society for Biomedical Diabetes Research
publisher.none.fl_str_mv Society for Biomedical Diabetes Research
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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