Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients

Autores
Meresman, Gabriela Fabiana; Olivares, Carla Noemi; Vighi, Susana; Alfie, Margarita; Irigoyen, Marcela; Etchepareborda, Juan J.
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Various endometrial abnormalities have been associated with luteal phase deficiency: a significant dyssynchrony in the maturation of the glandular epithelium and the stroma and a prevalence of out-of-phase endometrial biopsy specimens. Out-of phase endometrium is a controversial disorder related to failed implantation, infertility and early pregnancy loss. Given that the regulation of the apoptotic process in endometrium of luteal phase deficiency is still unknown, the aim of this study was to evaluate cell proliferation, apoptosis and the levels of the main effector caspase, caspase-3 in the luteal in-phase and out-of-phase endometrium.
Fil: Meresman, Gabriela Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Olivares, Carla Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Vighi, Susana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Alfie, Margarita. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Irigoyen, Marcela. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Etchepareborda, Juan J.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Materia
LUTHEAL PHASE DEFECT
ENDOMETRIUM
APOPTOSIS
CELL PROLIFERATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/79121
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patientsMeresman, Gabriela FabianaOlivares, Carla NoemiVighi, SusanaAlfie, MargaritaIrigoyen, MarcelaEtchepareborda, Juan J.LUTHEAL PHASE DEFECTENDOMETRIUMAPOPTOSISCELL PROLIFERATIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Various endometrial abnormalities have been associated with luteal phase deficiency: a significant dyssynchrony in the maturation of the glandular epithelium and the stroma and a prevalence of out-of-phase endometrial biopsy specimens. Out-of phase endometrium is a controversial disorder related to failed implantation, infertility and early pregnancy loss. Given that the regulation of the apoptotic process in endometrium of luteal phase deficiency is still unknown, the aim of this study was to evaluate cell proliferation, apoptosis and the levels of the main effector caspase, caspase-3 in the luteal in-phase and out-of-phase endometrium.Fil: Meresman, Gabriela Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Olivares, Carla Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Vighi, Susana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Alfie, Margarita. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Irigoyen, Marcela. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Etchepareborda, Juan J.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaBioMed Central2010-10-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/79121Meresman, Gabriela Fabiana; Olivares, Carla Noemi; Vighi, Susana; Alfie, Margarita; Irigoyen, Marcela; et al.; Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients; BioMed Central; Reproductive Biology And Endocrinology; 8; 22-10-2010; 126-1331477-7827CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://rbej.biomedcentral.com/articles/10.1186/1477-7827-8-126info:eu-repo/semantics/altIdentifier/doi/10.1186/1477-7827-8-126info:eu-repo/semantics/altIdentifier/pmid/20969784info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:26:13Zoai:ri.conicet.gov.ar:11336/79121instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:26:14.046CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
title Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
spellingShingle Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
Meresman, Gabriela Fabiana
LUTHEAL PHASE DEFECT
ENDOMETRIUM
APOPTOSIS
CELL PROLIFERATION
title_short Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
title_full Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
title_fullStr Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
title_full_unstemmed Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
title_sort Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients
dc.creator.none.fl_str_mv Meresman, Gabriela Fabiana
Olivares, Carla Noemi
Vighi, Susana
Alfie, Margarita
Irigoyen, Marcela
Etchepareborda, Juan J.
author Meresman, Gabriela Fabiana
author_facet Meresman, Gabriela Fabiana
Olivares, Carla Noemi
Vighi, Susana
Alfie, Margarita
Irigoyen, Marcela
Etchepareborda, Juan J.
author_role author
author2 Olivares, Carla Noemi
Vighi, Susana
Alfie, Margarita
Irigoyen, Marcela
Etchepareborda, Juan J.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv LUTHEAL PHASE DEFECT
ENDOMETRIUM
APOPTOSIS
CELL PROLIFERATION
topic LUTHEAL PHASE DEFECT
ENDOMETRIUM
APOPTOSIS
CELL PROLIFERATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Various endometrial abnormalities have been associated with luteal phase deficiency: a significant dyssynchrony in the maturation of the glandular epithelium and the stroma and a prevalence of out-of-phase endometrial biopsy specimens. Out-of phase endometrium is a controversial disorder related to failed implantation, infertility and early pregnancy loss. Given that the regulation of the apoptotic process in endometrium of luteal phase deficiency is still unknown, the aim of this study was to evaluate cell proliferation, apoptosis and the levels of the main effector caspase, caspase-3 in the luteal in-phase and out-of-phase endometrium.
Fil: Meresman, Gabriela Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Olivares, Carla Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Vighi, Susana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Alfie, Margarita. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Irigoyen, Marcela. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Etchepareborda, Juan J.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
description Various endometrial abnormalities have been associated with luteal phase deficiency: a significant dyssynchrony in the maturation of the glandular epithelium and the stroma and a prevalence of out-of-phase endometrial biopsy specimens. Out-of phase endometrium is a controversial disorder related to failed implantation, infertility and early pregnancy loss. Given that the regulation of the apoptotic process in endometrium of luteal phase deficiency is still unknown, the aim of this study was to evaluate cell proliferation, apoptosis and the levels of the main effector caspase, caspase-3 in the luteal in-phase and out-of-phase endometrium.
publishDate 2010
dc.date.none.fl_str_mv 2010-10-22
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/79121
Meresman, Gabriela Fabiana; Olivares, Carla Noemi; Vighi, Susana; Alfie, Margarita; Irigoyen, Marcela; et al.; Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients; BioMed Central; Reproductive Biology And Endocrinology; 8; 22-10-2010; 126-133
1477-7827
CONICET Digital
CONICET
url http://hdl.handle.net/11336/79121
identifier_str_mv Meresman, Gabriela Fabiana; Olivares, Carla Noemi; Vighi, Susana; Alfie, Margarita; Irigoyen, Marcela; et al.; Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients; BioMed Central; Reproductive Biology And Endocrinology; 8; 22-10-2010; 126-133
1477-7827
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://rbej.biomedcentral.com/articles/10.1186/1477-7827-8-126
info:eu-repo/semantics/altIdentifier/doi/10.1186/1477-7827-8-126
info:eu-repo/semantics/altIdentifier/pmid/20969784
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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