Light on the horizon: Current research and future perspectives in flow photochemistry

Autores
Politano, Fabrizio; Oksdath Mansilla, Gabriela
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Synthetic organic photochemistry is a powerful tool for creating both natural products and molecules with high structural complexity in a simple way and under mild conditions. However, because of the challenges in scaling-up, it has been difficult to apply a photochemical reaction in an industrial process. Flow chemistry provides an opportunity for better control over the conditions of the reaction and, additionally, improved reaction selectivity and enhanced reproducibility. Taking into account that significant interest has focused on the use of flow photochemistry as a method for the synthesis of heterocycles and its applications in target-oriented synthesis over the past few years, the aim of this review is to highlight recent efforts to apply flow photochemistry methodology to diverse reactions as a greener and more scalable process for the pharmaceutical and fine chemical industries. Additionally, the review highlights future perspectives in the development of scale-up strategies, combining photochemical reactions in the continuous-flow multistep synthesis of organic molecules, which is of interest for scientists and engineers alike.
Fil: Politano, Fabrizio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Oksdath Mansilla, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia
APIS
FLOW CHEMISTRY
GREEN PROCESSES
PHOTOCHEMICAL SYNTHESIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/85201
Acceder
id CONICETDig_19305a346ed13f73d0cc7da51803e13a
oai_identifier_str oai:ri.conicet.gov.ar:11336/85201
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Light on the horizon: Current research and future perspectives in flow photochemistryPolitano, FabrizioOksdath Mansilla, GabrielaAPISFLOW CHEMISTRYGREEN PROCESSESPHOTOCHEMICAL SYNTHESIShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Synthetic organic photochemistry is a powerful tool for creating both natural products and molecules with high structural complexity in a simple way and under mild conditions. However, because of the challenges in scaling-up, it has been difficult to apply a photochemical reaction in an industrial process. Flow chemistry provides an opportunity for better control over the conditions of the reaction and, additionally, improved reaction selectivity and enhanced reproducibility. Taking into account that significant interest has focused on the use of flow photochemistry as a method for the synthesis of heterocycles and its applications in target-oriented synthesis over the past few years, the aim of this review is to highlight recent efforts to apply flow photochemistry methodology to diverse reactions as a greener and more scalable process for the pharmaceutical and fine chemical industries. Additionally, the review highlights future perspectives in the development of scale-up strategies, combining photochemical reactions in the continuous-flow multistep synthesis of organic molecules, which is of interest for scientists and engineers alike.Fil: Politano, Fabrizio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Oksdath Mansilla, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaAmerican Chemical Society2018-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/85201Politano, Fabrizio; Oksdath Mansilla, Gabriela; Light on the horizon: Current research and future perspectives in flow photochemistry; American Chemical Society; Organic Process Research & Development; 22; 9; 9-2018; 1045-10621083-61601520-586XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acs.oprd.8b00213info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.oprd.8b00213info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:13:00Zoai:ri.conicet.gov.ar:11336/85201instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:13:00.525CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Light on the horizon: Current research and future perspectives in flow photochemistry
title Light on the horizon: Current research and future perspectives in flow photochemistry
spellingShingle Light on the horizon: Current research and future perspectives in flow photochemistry
Politano, Fabrizio
APIS
FLOW CHEMISTRY
GREEN PROCESSES
PHOTOCHEMICAL SYNTHESIS
title_short Light on the horizon: Current research and future perspectives in flow photochemistry
title_full Light on the horizon: Current research and future perspectives in flow photochemistry
title_fullStr Light on the horizon: Current research and future perspectives in flow photochemistry
title_full_unstemmed Light on the horizon: Current research and future perspectives in flow photochemistry
title_sort Light on the horizon: Current research and future perspectives in flow photochemistry
dc.creator.none.fl_str_mv Politano, Fabrizio
Oksdath Mansilla, Gabriela
author Politano, Fabrizio
author_facet Politano, Fabrizio
Oksdath Mansilla, Gabriela
author_role author
author2 Oksdath Mansilla, Gabriela
author2_role author
dc.subject.none.fl_str_mv APIS
FLOW CHEMISTRY
GREEN PROCESSES
PHOTOCHEMICAL SYNTHESIS
topic APIS
FLOW CHEMISTRY
GREEN PROCESSES
PHOTOCHEMICAL SYNTHESIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Synthetic organic photochemistry is a powerful tool for creating both natural products and molecules with high structural complexity in a simple way and under mild conditions. However, because of the challenges in scaling-up, it has been difficult to apply a photochemical reaction in an industrial process. Flow chemistry provides an opportunity for better control over the conditions of the reaction and, additionally, improved reaction selectivity and enhanced reproducibility. Taking into account that significant interest has focused on the use of flow photochemistry as a method for the synthesis of heterocycles and its applications in target-oriented synthesis over the past few years, the aim of this review is to highlight recent efforts to apply flow photochemistry methodology to diverse reactions as a greener and more scalable process for the pharmaceutical and fine chemical industries. Additionally, the review highlights future perspectives in the development of scale-up strategies, combining photochemical reactions in the continuous-flow multistep synthesis of organic molecules, which is of interest for scientists and engineers alike.
Fil: Politano, Fabrizio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Oksdath Mansilla, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description Synthetic organic photochemistry is a powerful tool for creating both natural products and molecules with high structural complexity in a simple way and under mild conditions. However, because of the challenges in scaling-up, it has been difficult to apply a photochemical reaction in an industrial process. Flow chemistry provides an opportunity for better control over the conditions of the reaction and, additionally, improved reaction selectivity and enhanced reproducibility. Taking into account that significant interest has focused on the use of flow photochemistry as a method for the synthesis of heterocycles and its applications in target-oriented synthesis over the past few years, the aim of this review is to highlight recent efforts to apply flow photochemistry methodology to diverse reactions as a greener and more scalable process for the pharmaceutical and fine chemical industries. Additionally, the review highlights future perspectives in the development of scale-up strategies, combining photochemical reactions in the continuous-flow multistep synthesis of organic molecules, which is of interest for scientists and engineers alike.
publishDate 2018
dc.date.none.fl_str_mv 2018-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/85201
Politano, Fabrizio; Oksdath Mansilla, Gabriela; Light on the horizon: Current research and future perspectives in flow photochemistry; American Chemical Society; Organic Process Research & Development; 22; 9; 9-2018; 1045-1062
1083-6160
1520-586X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/85201
identifier_str_mv Politano, Fabrizio; Oksdath Mansilla, Gabriela; Light on the horizon: Current research and future perspectives in flow photochemistry; American Chemical Society; Organic Process Research & Development; 22; 9; 9-2018; 1045-1062
1083-6160
1520-586X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acs.oprd.8b00213
info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.oprd.8b00213
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980683107008512
score 13.004268

Publicaciones similares