Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation
- Autores
- Gregorutti, Ricardo Walter; Grau, Jorge Enrique; Castrogiovanni, Daniel Cayetano; Parisi, Julieta Marcia; Reigosa, Miguel Antonio; Elsner, Cecilia Ines
- Año de publicación
- 2020
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background: Body fluids are highly corrosive as they contain chlorides and hydroxides ions, as well as salts, bacteria, proteins and dissolved oxygen. The pH of the body is usually around 7.4, although this value can vary in a range of 4 to 9 after surgery or because of haematomas, inflammations and infections. ASTM F745 (type 316L) stainless steel has been used for load bearing partial and total joint replacements and post trauma reconstructive surgeries. However, long exposure to the aggressive effect of chloride ion present in the human body, may increase the susceptibility to suffer localized corrosion. Although UNS S32750 has greater corrosion resistance to chloride ion, its magnetic characteristics inhibit its use in implantable devices. Nevertheless, this stainless steel could be used in temporary implants and orthodontic appliances such as brackets, wire arches and bands, due to its high resistance to corrosion, the greater mechanical resistance and the high capacity of plastic forming. Objectives: The objective was to evaluate the susceptibility to localized corrosion in simulated body fluid, in the pH range of 4 to 9. Another objective was to evaluate the cytotoxicity of Cr and Ni present in the chemical composition of both stainless steels. Cytocompatibility was also analysed by seeding cells on the surfaces of both stainless steels. Methods: Cyclic polariation test was performed to evaluate the susceptibility to localized corrosion in 0.9 wt% NaCl aqueous solution, at pH between 4 and 9, maintained at 37°C. For cytotoxicity evaluation, neutral red, MTT and collagen assays were performed using UMR-106 cell line. Cytocompatibility was analysed by seeding UMR-106 cells on the surfaces of both stainless steels. Results: F745-SS was more susceptible to suffer localized corrosion than UNS S32750. Although it showed a tendency to develop transpassive reactions at low pH, galvanostatic tests did not reveal the onset of localized corrosion. The results from the cytotoxicity assays indicated that no adverse effects were observed. UMR-106 osteoblastic cells showed high viability, however, a slight reduction in the collagen production was observed. The cytocompatibility was also satisfactory, since the cells seeded on the surfaces had adequate proliferation. Conclusion: F745-SS is more susceptible to suffer localized corrosion than UNS S32750 in the pH range between 4 and 9. UNS S32750 showed an extensive passive region, however, transpassive reactions were observed at lower pH. On the other hand, no cytotoxic effects were promoted by both stainless steels, although a slight reduction in collagen production was observed. Cells seeded on F745-SS and UNS S32750 surfaces had an acceptable proliferation, without evidence of changes in their morphology.
Fil: Gregorutti, Ricardo Walter. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Laboratorio de Entrenamiento Multidisciplinario para la Investigación Tecnológica; Argentina
Fil: Grau, Jorge Enrique. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Laboratorio de Entrenamiento Multidisciplinario para la Investigación Tecnológica; Argentina
Fil: Castrogiovanni, Daniel Cayetano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Parisi, Julieta Marcia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Reigosa, Miguel Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Elsner, Cecilia Ines. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones en Tecnología de Pinturas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigaciones en Tecnología de Pinturas; Argentina - Materia
-
BIOMATERIALS
STAINLESS STEELS
LOCALIZED CORROSION
TRANSPASSIVE REACTIONS CYTOTOXICITY
CYTOCOMPATIBILITY
PROLIFERATION - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/146757
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Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluationGregorutti, Ricardo WalterGrau, Jorge EnriqueCastrogiovanni, Daniel CayetanoParisi, Julieta MarciaReigosa, Miguel AntonioElsner, Cecilia InesBIOMATERIALSSTAINLESS STEELSLOCALIZED CORROSIONTRANSPASSIVE REACTIONS CYTOTOXICITYCYTOCOMPATIBILITYPROLIFERATIONhttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2Background: Body fluids are highly corrosive as they contain chlorides and hydroxides ions, as well as salts, bacteria, proteins and dissolved oxygen. The pH of the body is usually around 7.4, although this value can vary in a range of 4 to 9 after surgery or because of haematomas, inflammations and infections. ASTM F745 (type 316L) stainless steel has been used for load bearing partial and total joint replacements and post trauma reconstructive surgeries. However, long exposure to the aggressive effect of chloride ion present in the human body, may increase the susceptibility to suffer localized corrosion. Although UNS S32750 has greater corrosion resistance to chloride ion, its magnetic characteristics inhibit its use in implantable devices. Nevertheless, this stainless steel could be used in temporary implants and orthodontic appliances such as brackets, wire arches and bands, due to its high resistance to corrosion, the greater mechanical resistance and the high capacity of plastic forming. Objectives: The objective was to evaluate the susceptibility to localized corrosion in simulated body fluid, in the pH range of 4 to 9. Another objective was to evaluate the cytotoxicity of Cr and Ni present in the chemical composition of both stainless steels. Cytocompatibility was also analysed by seeding cells on the surfaces of both stainless steels. Methods: Cyclic polariation test was performed to evaluate the susceptibility to localized corrosion in 0.9 wt% NaCl aqueous solution, at pH between 4 and 9, maintained at 37°C. For cytotoxicity evaluation, neutral red, MTT and collagen assays were performed using UMR-106 cell line. Cytocompatibility was analysed by seeding UMR-106 cells on the surfaces of both stainless steels. Results: F745-SS was more susceptible to suffer localized corrosion than UNS S32750. Although it showed a tendency to develop transpassive reactions at low pH, galvanostatic tests did not reveal the onset of localized corrosion. The results from the cytotoxicity assays indicated that no adverse effects were observed. UMR-106 osteoblastic cells showed high viability, however, a slight reduction in the collagen production was observed. The cytocompatibility was also satisfactory, since the cells seeded on the surfaces had adequate proliferation. Conclusion: F745-SS is more susceptible to suffer localized corrosion than UNS S32750 in the pH range between 4 and 9. UNS S32750 showed an extensive passive region, however, transpassive reactions were observed at lower pH. On the other hand, no cytotoxic effects were promoted by both stainless steels, although a slight reduction in collagen production was observed. Cells seeded on F745-SS and UNS S32750 surfaces had an acceptable proliferation, without evidence of changes in their morphology.Fil: Gregorutti, Ricardo Walter. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Laboratorio de Entrenamiento Multidisciplinario para la Investigación Tecnológica; ArgentinaFil: Grau, Jorge Enrique. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Laboratorio de Entrenamiento Multidisciplinario para la Investigación Tecnológica; ArgentinaFil: Castrogiovanni, Daniel Cayetano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Parisi, Julieta Marcia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Reigosa, Miguel Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Elsner, Cecilia Ines. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones en Tecnología de Pinturas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigaciones en Tecnología de Pinturas; ArgentinaBenthan Science2020-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/146757Gregorutti, Ricardo Walter; Grau, Jorge Enrique; Castrogiovanni, Daniel Cayetano; Parisi, Julieta Marcia; Reigosa, Miguel Antonio; et al.; Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation; Benthan Science; Innovations in Corrosion and Materials Science; 10; 1; 5-2020; 47-572352-0949CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/182219/articleinfo:eu-repo/semantics/altIdentifier/doi/10.2174/2352094910999200523153527info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:36:57Zoai:ri.conicet.gov.ar:11336/146757instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:36:57.354CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
title |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
spellingShingle |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation Gregorutti, Ricardo Walter BIOMATERIALS STAINLESS STEELS LOCALIZED CORROSION TRANSPASSIVE REACTIONS CYTOTOXICITY CYTOCOMPATIBILITY PROLIFERATION |
title_short |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
title_full |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
title_fullStr |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
title_full_unstemmed |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
title_sort |
Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation |
dc.creator.none.fl_str_mv |
Gregorutti, Ricardo Walter Grau, Jorge Enrique Castrogiovanni, Daniel Cayetano Parisi, Julieta Marcia Reigosa, Miguel Antonio Elsner, Cecilia Ines |
author |
Gregorutti, Ricardo Walter |
author_facet |
Gregorutti, Ricardo Walter Grau, Jorge Enrique Castrogiovanni, Daniel Cayetano Parisi, Julieta Marcia Reigosa, Miguel Antonio Elsner, Cecilia Ines |
author_role |
author |
author2 |
Grau, Jorge Enrique Castrogiovanni, Daniel Cayetano Parisi, Julieta Marcia Reigosa, Miguel Antonio Elsner, Cecilia Ines |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
BIOMATERIALS STAINLESS STEELS LOCALIZED CORROSION TRANSPASSIVE REACTIONS CYTOTOXICITY CYTOCOMPATIBILITY PROLIFERATION |
topic |
BIOMATERIALS STAINLESS STEELS LOCALIZED CORROSION TRANSPASSIVE REACTIONS CYTOTOXICITY CYTOCOMPATIBILITY PROLIFERATION |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.5 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
Background: Body fluids are highly corrosive as they contain chlorides and hydroxides ions, as well as salts, bacteria, proteins and dissolved oxygen. The pH of the body is usually around 7.4, although this value can vary in a range of 4 to 9 after surgery or because of haematomas, inflammations and infections. ASTM F745 (type 316L) stainless steel has been used for load bearing partial and total joint replacements and post trauma reconstructive surgeries. However, long exposure to the aggressive effect of chloride ion present in the human body, may increase the susceptibility to suffer localized corrosion. Although UNS S32750 has greater corrosion resistance to chloride ion, its magnetic characteristics inhibit its use in implantable devices. Nevertheless, this stainless steel could be used in temporary implants and orthodontic appliances such as brackets, wire arches and bands, due to its high resistance to corrosion, the greater mechanical resistance and the high capacity of plastic forming. Objectives: The objective was to evaluate the susceptibility to localized corrosion in simulated body fluid, in the pH range of 4 to 9. Another objective was to evaluate the cytotoxicity of Cr and Ni present in the chemical composition of both stainless steels. Cytocompatibility was also analysed by seeding cells on the surfaces of both stainless steels. Methods: Cyclic polariation test was performed to evaluate the susceptibility to localized corrosion in 0.9 wt% NaCl aqueous solution, at pH between 4 and 9, maintained at 37°C. For cytotoxicity evaluation, neutral red, MTT and collagen assays were performed using UMR-106 cell line. Cytocompatibility was analysed by seeding UMR-106 cells on the surfaces of both stainless steels. Results: F745-SS was more susceptible to suffer localized corrosion than UNS S32750. Although it showed a tendency to develop transpassive reactions at low pH, galvanostatic tests did not reveal the onset of localized corrosion. The results from the cytotoxicity assays indicated that no adverse effects were observed. UMR-106 osteoblastic cells showed high viability, however, a slight reduction in the collagen production was observed. The cytocompatibility was also satisfactory, since the cells seeded on the surfaces had adequate proliferation. Conclusion: F745-SS is more susceptible to suffer localized corrosion than UNS S32750 in the pH range between 4 and 9. UNS S32750 showed an extensive passive region, however, transpassive reactions were observed at lower pH. On the other hand, no cytotoxic effects were promoted by both stainless steels, although a slight reduction in collagen production was observed. Cells seeded on F745-SS and UNS S32750 surfaces had an acceptable proliferation, without evidence of changes in their morphology. Fil: Gregorutti, Ricardo Walter. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Laboratorio de Entrenamiento Multidisciplinario para la Investigación Tecnológica; Argentina Fil: Grau, Jorge Enrique. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Laboratorio de Entrenamiento Multidisciplinario para la Investigación Tecnológica; Argentina Fil: Castrogiovanni, Daniel Cayetano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina Fil: Parisi, Julieta Marcia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina Fil: Reigosa, Miguel Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina Fil: Elsner, Cecilia Ines. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones en Tecnología de Pinturas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigaciones en Tecnología de Pinturas; Argentina |
description |
Background: Body fluids are highly corrosive as they contain chlorides and hydroxides ions, as well as salts, bacteria, proteins and dissolved oxygen. The pH of the body is usually around 7.4, although this value can vary in a range of 4 to 9 after surgery or because of haematomas, inflammations and infections. ASTM F745 (type 316L) stainless steel has been used for load bearing partial and total joint replacements and post trauma reconstructive surgeries. However, long exposure to the aggressive effect of chloride ion present in the human body, may increase the susceptibility to suffer localized corrosion. Although UNS S32750 has greater corrosion resistance to chloride ion, its magnetic characteristics inhibit its use in implantable devices. Nevertheless, this stainless steel could be used in temporary implants and orthodontic appliances such as brackets, wire arches and bands, due to its high resistance to corrosion, the greater mechanical resistance and the high capacity of plastic forming. Objectives: The objective was to evaluate the susceptibility to localized corrosion in simulated body fluid, in the pH range of 4 to 9. Another objective was to evaluate the cytotoxicity of Cr and Ni present in the chemical composition of both stainless steels. Cytocompatibility was also analysed by seeding cells on the surfaces of both stainless steels. Methods: Cyclic polariation test was performed to evaluate the susceptibility to localized corrosion in 0.9 wt% NaCl aqueous solution, at pH between 4 and 9, maintained at 37°C. For cytotoxicity evaluation, neutral red, MTT and collagen assays were performed using UMR-106 cell line. Cytocompatibility was analysed by seeding UMR-106 cells on the surfaces of both stainless steels. Results: F745-SS was more susceptible to suffer localized corrosion than UNS S32750. Although it showed a tendency to develop transpassive reactions at low pH, galvanostatic tests did not reveal the onset of localized corrosion. The results from the cytotoxicity assays indicated that no adverse effects were observed. UMR-106 osteoblastic cells showed high viability, however, a slight reduction in the collagen production was observed. The cytocompatibility was also satisfactory, since the cells seeded on the surfaces had adequate proliferation. Conclusion: F745-SS is more susceptible to suffer localized corrosion than UNS S32750 in the pH range between 4 and 9. UNS S32750 showed an extensive passive region, however, transpassive reactions were observed at lower pH. On the other hand, no cytotoxic effects were promoted by both stainless steels, although a slight reduction in collagen production was observed. Cells seeded on F745-SS and UNS S32750 surfaces had an acceptable proliferation, without evidence of changes in their morphology. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-05 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/146757 Gregorutti, Ricardo Walter; Grau, Jorge Enrique; Castrogiovanni, Daniel Cayetano; Parisi, Julieta Marcia; Reigosa, Miguel Antonio; et al.; Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation; Benthan Science; Innovations in Corrosion and Materials Science; 10; 1; 5-2020; 47-57 2352-0949 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/146757 |
identifier_str_mv |
Gregorutti, Ricardo Walter; Grau, Jorge Enrique; Castrogiovanni, Daniel Cayetano; Parisi, Julieta Marcia; Reigosa, Miguel Antonio; et al.; Susceptibility to localized corrosion of ASTM F745 and UNS S32750 stainless steels. influence of pH and cytotoxicity evaluation; Benthan Science; Innovations in Corrosion and Materials Science; 10; 1; 5-2020; 47-57 2352-0949 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/182219/article info:eu-repo/semantics/altIdentifier/doi/10.2174/2352094910999200523153527 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Benthan Science |
publisher.none.fl_str_mv |
Benthan Science |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |