ELM—the eukaryotic linear motif resource in 2020

Autores
Kumar, Manjeet; Gouw, Marc; Michael, Sushama; Sámano-Sánchez, Hugo; Pancsa, Rita; Glavina, Juliana; Diakogianni, Athina; Valverde, Jesús Alvarado; Bukirova, Dayana; Calyseva, Jelena; Palopoli, Nicolás; Davey, Norman E.; Chemes, Lucia Beatriz; Gibson, Toby J
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular biology community for investigating functional regions in many proteins. In this update, we have added 21 novel motif classes, made major revisions to 12 motif classes and added >400 new instances mostly focused on DNA damage, the cytoskeleton, SH2-binding phosphotyrosine motifs and motif mimicry by pathogenic bacterial effector proteins. The current release of the ELM database contains 289 motif classes and 3523 individual protein motif instances manually curated from 3467 scientific publications. ELM is available at: http://elm.eu.org.
Fil: Kumar, Manjeet. European Molecular Biology Laboratory; Alemania
Fil: Gouw, Marc. European Molecular Biology Laboratory; Alemania
Fil: Michael, Sushama. European Molecular Biology Laboratory; Alemania
Fil: Sámano-Sánchez, Hugo. European Molecular Biology Laboratory; Alemania
Fil: Pancsa, Rita. Research Centre for Natural Sciences; Hungría
Fil: Glavina, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina
Fil: Diakogianni, Athina. European Molecular Biology Laboratory; Alemania
Fil: Valverde, Jesús Alvarado. European Molecular Biology Laboratory; Alemania
Fil: Bukirova, Dayana. European Molecular Biology Laboratory; Alemania
Fil: Calyseva, Jelena. European Molecular Biology Laboratory; Alemania
Fil: Palopoli, Nicolás. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Davey, Norman E.. Institute Of Cancer Research; Reino Unido
Fil: Chemes, Lucia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina
Fil: Gibson, Toby J. European Molecular Biology Laboratory; Alemania
Materia
LINEAR MOTIFS
EUKARYOTIC
DATABASE
DISORDERED PROTEINS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/124579
Acceder
id CONICETDig_17221e9cbd2fcec1d3c34a0dec7f3c26
oai_identifier_str oai:ri.conicet.gov.ar:11336/124579
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling ELM—the eukaryotic linear motif resource in 2020Kumar, ManjeetGouw, MarcMichael, SushamaSámano-Sánchez, HugoPancsa, RitaGlavina, JulianaDiakogianni, AthinaValverde, Jesús AlvaradoBukirova, DayanaCalyseva, JelenaPalopoli, NicolásDavey, Norman E.Chemes, Lucia BeatrizGibson, Toby JLINEAR MOTIFSEUKARYOTICDATABASEDISORDERED PROTEINShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular biology community for investigating functional regions in many proteins. In this update, we have added 21 novel motif classes, made major revisions to 12 motif classes and added >400 new instances mostly focused on DNA damage, the cytoskeleton, SH2-binding phosphotyrosine motifs and motif mimicry by pathogenic bacterial effector proteins. The current release of the ELM database contains 289 motif classes and 3523 individual protein motif instances manually curated from 3467 scientific publications. ELM is available at: http://elm.eu.org.Fil: Kumar, Manjeet. European Molecular Biology Laboratory; AlemaniaFil: Gouw, Marc. European Molecular Biology Laboratory; AlemaniaFil: Michael, Sushama. European Molecular Biology Laboratory; AlemaniaFil: Sámano-Sánchez, Hugo. European Molecular Biology Laboratory; AlemaniaFil: Pancsa, Rita. Research Centre for Natural Sciences; HungríaFil: Glavina, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; ArgentinaFil: Diakogianni, Athina. European Molecular Biology Laboratory; AlemaniaFil: Valverde, Jesús Alvarado. European Molecular Biology Laboratory; AlemaniaFil: Bukirova, Dayana. European Molecular Biology Laboratory; AlemaniaFil: Calyseva, Jelena. European Molecular Biology Laboratory; AlemaniaFil: Palopoli, Nicolás. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Davey, Norman E.. Institute Of Cancer Research; Reino UnidoFil: Chemes, Lucia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; ArgentinaFil: Gibson, Toby J. European Molecular Biology Laboratory; AlemaniaOxford University Press2019-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/124579Kumar, Manjeet; Gouw, Marc; Michael, Sushama; Sámano-Sánchez, Hugo; Pancsa, Rita; et al.; ELM—the eukaryotic linear motif resource in 2020; Oxford University Press; Nucleic Acids Research; 48; D1; 11-2019; D296-D3060305-10481362-4962CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz1030/5611669info:eu-repo/semantics/altIdentifier/doi/10.1093/nar/gkz1030info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:15:48Zoai:ri.conicet.gov.ar:11336/124579instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:15:48.687CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv ELM—the eukaryotic linear motif resource in 2020
title ELM—the eukaryotic linear motif resource in 2020
spellingShingle ELM—the eukaryotic linear motif resource in 2020
Kumar, Manjeet
LINEAR MOTIFS
EUKARYOTIC
DATABASE
DISORDERED PROTEINS
title_short ELM—the eukaryotic linear motif resource in 2020
title_full ELM—the eukaryotic linear motif resource in 2020
title_fullStr ELM—the eukaryotic linear motif resource in 2020
title_full_unstemmed ELM—the eukaryotic linear motif resource in 2020
title_sort ELM—the eukaryotic linear motif resource in 2020
dc.creator.none.fl_str_mv Kumar, Manjeet
Gouw, Marc
Michael, Sushama
Sámano-Sánchez, Hugo
Pancsa, Rita
Glavina, Juliana
Diakogianni, Athina
Valverde, Jesús Alvarado
Bukirova, Dayana
Calyseva, Jelena
Palopoli, Nicolás
Davey, Norman E.
Chemes, Lucia Beatriz
Gibson, Toby J
author Kumar, Manjeet
author_facet Kumar, Manjeet
Gouw, Marc
Michael, Sushama
Sámano-Sánchez, Hugo
Pancsa, Rita
Glavina, Juliana
Diakogianni, Athina
Valverde, Jesús Alvarado
Bukirova, Dayana
Calyseva, Jelena
Palopoli, Nicolás
Davey, Norman E.
Chemes, Lucia Beatriz
Gibson, Toby J
author_role author
author2 Gouw, Marc
Michael, Sushama
Sámano-Sánchez, Hugo
Pancsa, Rita
Glavina, Juliana
Diakogianni, Athina
Valverde, Jesús Alvarado
Bukirova, Dayana
Calyseva, Jelena
Palopoli, Nicolás
Davey, Norman E.
Chemes, Lucia Beatriz
Gibson, Toby J
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv LINEAR MOTIFS
EUKARYOTIC
DATABASE
DISORDERED PROTEINS
topic LINEAR MOTIFS
EUKARYOTIC
DATABASE
DISORDERED PROTEINS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular biology community for investigating functional regions in many proteins. In this update, we have added 21 novel motif classes, made major revisions to 12 motif classes and added >400 new instances mostly focused on DNA damage, the cytoskeleton, SH2-binding phosphotyrosine motifs and motif mimicry by pathogenic bacterial effector proteins. The current release of the ELM database contains 289 motif classes and 3523 individual protein motif instances manually curated from 3467 scientific publications. ELM is available at: http://elm.eu.org.
Fil: Kumar, Manjeet. European Molecular Biology Laboratory; Alemania
Fil: Gouw, Marc. European Molecular Biology Laboratory; Alemania
Fil: Michael, Sushama. European Molecular Biology Laboratory; Alemania
Fil: Sámano-Sánchez, Hugo. European Molecular Biology Laboratory; Alemania
Fil: Pancsa, Rita. Research Centre for Natural Sciences; Hungría
Fil: Glavina, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina
Fil: Diakogianni, Athina. European Molecular Biology Laboratory; Alemania
Fil: Valverde, Jesús Alvarado. European Molecular Biology Laboratory; Alemania
Fil: Bukirova, Dayana. European Molecular Biology Laboratory; Alemania
Fil: Calyseva, Jelena. European Molecular Biology Laboratory; Alemania
Fil: Palopoli, Nicolás. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Davey, Norman E.. Institute Of Cancer Research; Reino Unido
Fil: Chemes, Lucia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina
Fil: Gibson, Toby J. European Molecular Biology Laboratory; Alemania
description The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular biology community for investigating functional regions in many proteins. In this update, we have added 21 novel motif classes, made major revisions to 12 motif classes and added >400 new instances mostly focused on DNA damage, the cytoskeleton, SH2-binding phosphotyrosine motifs and motif mimicry by pathogenic bacterial effector proteins. The current release of the ELM database contains 289 motif classes and 3523 individual protein motif instances manually curated from 3467 scientific publications. ELM is available at: http://elm.eu.org.
publishDate 2019
dc.date.none.fl_str_mv 2019-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/124579
Kumar, Manjeet; Gouw, Marc; Michael, Sushama; Sámano-Sánchez, Hugo; Pancsa, Rita; et al.; ELM—the eukaryotic linear motif resource in 2020; Oxford University Press; Nucleic Acids Research; 48; D1; 11-2019; D296-D306
0305-1048
1362-4962
CONICET Digital
CONICET
url http://hdl.handle.net/11336/124579
identifier_str_mv Kumar, Manjeet; Gouw, Marc; Michael, Sushama; Sámano-Sánchez, Hugo; Pancsa, Rita; et al.; ELM—the eukaryotic linear motif resource in 2020; Oxford University Press; Nucleic Acids Research; 48; D1; 11-2019; D296-D306
0305-1048
1362-4962
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz1030/5611669
info:eu-repo/semantics/altIdentifier/doi/10.1093/nar/gkz1030
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980855432085504
score 12.993085

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